Search results for " Mapping"

showing 10 items of 1411 documents

Pan-cancer analysis of whole genomes

2020

Publisher's version (útgefin grein)

Maletert promoter mutationsCancer development and immune defence Radboud Institute for Molecular Life Sciences [Radboudumc 2]DNA Mutational AnalysisNormal tissuesystematic analysisGermlineTranscriptome0302 clinical medicineAetiologyCàncerCellular SenescenceCancer0303 health sciencesdna-damageMassive parallel sequencingPan cancerREARRANGEMENTSHigh-Throughput Nucleotide SequencingGenomicsSciences bio-médicales et agricolesTelomereCOMPREHENSIVE3. Good healthTERT PROMOTER MUTATIONSsignatures030220 oncology & carcinogenesisScience & Technology - Other TopicsErfðarannsóknirHuman:Informàtica::Aplicacions de la informàtica::Bioinformàtica [Àrees temàtiques de la UPC]EvolutionRNA SplicingGenomicsArticleEvolution MolecularStructural variationRC025403 medical and health sciencesSDG 3 - Good Health and Well-beingGeneticgenomicsSYSTEMATIC ANALYSISGeneticsGenomics--Databases.HumansGenetic TestingMolecular BiologySIGNATURESWhole genome sequencing1000 MultidisciplinaryChromothripsisScience & TechnologyRC0254 Neoplasms. Tumors. Oncology (including Cancer)Information DisseminationResearchInstitutes_Networks_Beacons/mcrcPreventionBiology and Life SciencesMolecularOncogenesCloud Computingmedicine.diseaseGenòmicaCompute cloudsMutation570 Life sciences; biologyCOMPREHENSIVE CHARACTERIZATIONGenèticaWhole Genome Sequencing--methodsBackground informationDNA Mutational Analysis ; Evolution ; Genetic / genetics ; Genome ; Genomics ; Germ-Line Mutation / genetics ; High-Throughput Nucleotide Sequencing ; Human / genetics ; Humans ; ICGC/TCGA Pan-Cancer Analysis of Whole Genomes ConsortiumMedizinGenomeWhole-genomeGenome mappingNeoplasms2.1 Biological and endogenous factorsPromoter Regions GeneticCàncer -- Aspectes genèticsTelomeraseGeneticsWomen's cancers Radboud Institute for Molecular Life Sciences [Radboudumc 17]MultidisciplinaryChromothripsisGenomeManchester Cancer Research Centregenomics cancer profiling3rd-DAS10124 Institute of Molecular Life SciencesWomen's cancers Radboud Institute for Health Sciences [Radboudumc 17]Multidisciplinary SciencesParallel sequencingICGC/TCGA Pan-Cancer Analysis of Whole Genomes ConsortiumFemaleprofilingMedical GeneticsEngineering sciences. TechnologyBiotechnologyGeneral Science & TechnologyThe Cancer Genome Atlas610 Medicine & healthComputational biologyQH426 GeneticsBiologyConsortium of the International Cancer Genome ConsortiumPromoter RegionsGermline mutationPan-cancer analysisKrabbameinsrannsóknirmedicinecancerddc:610QH426Germ-Line MutationMedicinsk genetikKrabbamein030304 developmental biologyCell ProliferationLANDSCAPEGenome Humancomprehensive characterizationPan-cancer analysis of whole genomesPoint mutationHuman GenomeCancerReproducibility of ResultsSOMATIC MUTATIONSEVOLUTIONCancer sequencing Chromothripsis telomereDNA-DAMAGEMutagenesisPATTERNS3111 BiomedicineCHARACTERIZATION
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Long-Term Response to Cholinesterase Inhibitor Treatment Is Related to Functional MRI Response in Alzheimer's Disease.

2015

<b><i>Background:</i></b> Treatment of Alzheimer's disease (AD) with cholinesterase inhibitors (ChEI) enhances cholinergic activity and alleviates clinical symptoms. However, there is variation in the clinical response as well as system level changes revealed by functional MRI (fMRI) studies. <b><i>Methods:</i></b> We investigated 18 newly diagnosed mild AD patients with fMRI using a face recognition task after a single oral dose of rivastigmine, a single dose of placebo and 1-month treatment with rivastigmine. The clinical follow-up took place at 6 and 12 months. <b><i>Results:</i></b> MMSE score difference between bas…

Malevsual processingCognitive NeuroscienceRivastigmineDiseasePharmacologyNeuropsychological TestsAlzheimerin tautimmoryta3112behavioral disciplines and activitiesBrain mappingAlzheimer DiseasemedicineHumansCholinesteraseAgedRivastigmineAged 80 and overmuistisairaudetBrain Mappingmedicine.diagnostic_testbiologyBrainMagnetic resonance imagingMiddle Agedmedicine.diseaseMagnetic Resonance Imagingta3124Psychiatry and Mental healthLong term responsecolinesterase inhibitorbiology.proteinCholinergicFemaleCholinesterase InhibitorsGeriatrics and GerontologyAlzheimer's diseasePsychologyAlzheimer’s diseaseNeurosciencepsychological phenomena and processesmgnetic resonance imagingmedicine.drugDementia and geriatric cognitive disorders
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Mappings of finite distortion from generalized manifolds

2014

We give a definition for mappings of finite distortion from a generalized manifold with controlled geometry to a Euclidean space. We prove that the basic properties of mappings of finite distortion are valid in this context. In particular, we show that under the same assumptions as in the Euclidean case, mappings of finite distortion are open and discrete.

Mappings of finite distortionDistortionQuasiconformal mappingsGeometry and TopologyTopologyMathematics
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Time‐gated Raman and laser‐induced breakdown spectroscopy in mapping of eudialyte and catapleiite

2019

Abstract Raman analysis of rock samples containing rare earth elements (REEs) is challenging due to the strong fluorescence, which may mask the weaker Raman signal. In this research, time‐gated (TG) Raman has been applied to the construction of the mineral distribution map from REE‐bearing rock. With TG Raman, material is excited with a short subnanosecond laser pulse, and the Raman signal is collected within a picosecond‐scale time window prior to the formation of a strong fluorescent signal by means of single‐photon avalanche diode array. This allows signal readout with a significantly reduced fluorescence background. TG Raman maps are used to reveal the location of valuable minerals and …

Materials science010401 analytical chemistryAnalytical chemistryEudialyteMineral mappingtime‐gated Raman02 engineering and technologyengineering.material021001 nanoscience & nanotechnology01 natural sciences0104 chemical sciencesrock analysissymbols.namesakelaser‐induced breakdown spectroscopy (LIBS)symbolsengineeringGeneral Materials ScienceLaser-induced breakdown spectroscopymineral mapping0210 nano-technologyRaman spectroscopySpectroscopyREE‐bearing mineralsJournal of Raman Spectroscopy
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Detection of planar defects caused by ion irradiation in Si using molecular dynamics

2007

We have analyzed the evolution of defects caused by self-irradiation of crystalline silicon. A classical molecular dynamics simulation was followed by defect analysis using the Pixel Mapping (PM) method. The PM identified {311} planar defects and long-chain structures of the so-called interstitial chains following low energy (1 keV) ion impact. The areal density obtained from simulation of self-interstitial atoms was about two thirds of that of experiments reported in the literature [Jpn. J. Appl. Phys. 30 (1991) L639], while the atomic configuration on respective planes agreed exactly.

Materials scienceIon beamPixel mappingSurfaces and InterfacesGeneral ChemistryCondensed Matter PhysicsSurfaces Coatings and FilmsIonMolecular dynamicsPlanarMaterials ChemistryIrradiationCrystalline siliconArea densityAtomic physicsSurface and Coatings Technology
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Smartphone snapshot mapping of skin chromophores under triple-wavelength laser illumination

2017

Abstract Chromophore distribution maps are useful tools for skin malformation severity assessment and for monitoring of skin recovery after burns, surgeries, and other interactions. The chromophore maps can be obtained by processing several spectral images of skin, e.g., captured by hyperspectral or multispectral cameras during seconds or even minutes. To avoid motion artifacts and simplify the procedure, a single-snapshot technique for mapping melanin, oxyhemoglobin, and deoxyhemoglobin of in-vivo skin by a smartphone under simultaneous three-wavelength (448–532–659 nm) laser illumination is proposed and examined. Three monochromatic spectral images related to the illumination wavelengths …

Materials scienceLightMonte Carlo methodMultispectral imageBiomedical Engineeringsmartphone applicationsImage processing02 engineering and technologyDermatologylaser illumination design01 natural sciencesSkin Diseaseslaw.invention010309 opticsBiomaterialsOpticslaw0103 physical sciencesmultispectral imagingHumansLightingSkinbusiness.industryLasersHyperspectral imagingskin chromophore mappingChromophore021001 nanoscience & nanotechnologyLaserAtomic and Molecular Physics and OpticsElectronic Optical and Magnetic MaterialsRGB color modelMonochromatic colorSmartphone0210 nano-technologybusiness
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Raman Mapping Applied to Reveal Internal Structures of Natural Minerals

2003

Materials scienceMineralogyRaman mappingNatural mineralInstrumentationMicroscopy and Microanalysis
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A Raman spectroscopy study of the oxidation processes in synthetic chromite FeCr2O4

2020

Abstract A crystal of synthetic chromite FeCr2O4 has been annealed in air at 700 °C for 50 days at room pressure in order to study physical-chemical changes. After the annealing treatment, Scanning Electron Microscopy (SEM) images of the polished surface of the sample showed areas of different composition. Detailed Raman mapping revealed that the annealed chromite undergoes an oxidation process, proceeding inwards from the outer surface and leading to the transformation of chromite to magnetite, and ultimately to hematite. The oxidation process also leads to the formation of trellis-like lines, arguably via stress-related mechanisms associated with the phase transformation and consequent vo…

Materials scienceRaman mappingAnnealing (metallurgy)Scanning electron microscopeSpinelHematite02 engineering and technologyRaman mapping01 natural sciencesMagnetitechemistry.chemical_compoundsymbols.namesake0103 physical sciencesOxidationMaterials ChemistryMagnetite010302 applied physicsProcess Chemistry and TechnologyChromiteHematite021001 nanoscience & nanotechnologySpinel; Chromite; Magnetite; Hematite; Oxidation; Raman mappingSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialschemistryChemical engineeringvisual_artCeramics and Compositessymbolsvisual_art.visual_art_mediumChromiteOxidation process0210 nano-technologyRaman spectroscopy
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Singular value decomposition approach to the yttrium occurrence in mineral maps of rare earth element ores using laser-induced breakdown spectroscopy

2017

Laser-induced breakdown spectroscopy (LIBS) has been used in analysis of rare earth element (REE) ores from the geological formation of Norra Kärr Alkaline Complex in southern Sweden. Yttrium has been detected in eudialyte (Na15 Ca6(Fe,Mn)3 Zr3Si(Si25O73)(O,OH,H2O)3 (OH,Cl)2) and catapleiite (Ca/Na2ZrSi3O9·2H2O). Singular value decomposition (SVD) has been employed in classification of the minerals in the rock samples and maps representing the mineralogy in the sampled area have been constructed. Based on the SVD classification the percentage of the yttrium-bearing ore minerals can be calculated even in fine-grained rock samples. peerReviewed

Materials sciencespektroskopiaEudialyteMineralogychemistry.chemical_elementengineering.material010502 geochemistry & geophysics01 natural sciencesAnalytical ChemistryGeological formationSingular value decompositionmineraalitLaser-induced breakdown spectroscopySpectroscopyInstrumentationta116Spectroscopy0105 earth and related environmental sciencesgeographygeography.geographical_feature_categoryMineralRare-earth element010401 analytical chemistrysingular value decompositionYttriumharvinaiset maametallitAtomic and Molecular Physics and Optics0104 chemical sciencesyttriumrock analysischemistryanalyysiengineeringlaser-induced breakdown spectroscopy (LIBS)mineral mappingSpectrochimica Acta Part B: Atomic Spectroscopy
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Elastoplastic analysis by active macro-zones with linear kinematic hardening and von Mises materials.

2014

In this paper a strategy to perform elastoplastic analysis with linear kinematic hardening for von Mises materials under plane strain conditions is shown. The proposed approach works with the Symmetric Galerkin Boundary Element Method applied to multidomain problems using a mixed variables approach, to obtain a more stringent solution. The elastoplastic analysis is carried out as the response to the loads and the plastic strains, the latter evaluated through the self-equilibrium stress matrix. This matrix is used both, in the predictor phase, for trial stress evaluation and, in the corrector phase, for solving a nonlinear global system which provides the elastoplastic solution of the active…

Mathematical optimizationApplied MathematicsComputational MathematicsNonlinear systemsymbols.namesakeMatrix (mathematics)Consistency (statistics)Multidomain SGBEM Self-equilibrium stressActive macro-zones Hardening von Mises materials Return mapping algorithm.Jacobian matrix and determinantsymbolsApplied mathematicsvon Mises yield criterionMultidomain SGBEM Self-equilibrium stress Active macro-zonesHardening von Mises materials Return mapping algorithmGalerkin methodSettore ICAR/08 - Scienza Delle CostruzioniBoundary element methodPlane stressMathematics
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