Search results for " Maps"

showing 10 items of 198 documents

Electrical Coupling in Ensembles of Nonexcitable Cells: Modeling the Spatial Map of Single Cell Potentials

2015

We analyze the coupling of model nonexcitable (non-neural) cells assuming that the cell membrane potential is the basic individual property. We obtain this potential on the basis of the inward and outward rectifying voltage-gated channels characteristic of cell membranes. We concentrate on the electrical coupling of a cell ensemble rather than on the biochemical and mechanical characteristics of the individual cells, obtain the map of single cell potentials using simple assumptions, and suggest procedures to collectively modify this spatial map. The response of the cell ensemble to an external perturbation and the consequences of cell isolation, heterogeneity, and ensemble size are also ana…

Membrane potentialChemistryCellNanotechnologyCell CommunicationHydrogen-Ion ConcentrationModels BiologicalIon ChannelsMembrane PotentialsQuantitative Biology::Cell BehaviorSurfaces Coatings and FilmsCoupling (electronics)medicine.anatomical_structureMembraneMaterials ChemistrymedicineSpatial mapsPhysical and Theoretical ChemistryExtracellular SpaceLipid bilayerBiological systemElectromagnetic PhenomenaIon channelBiophysical chemistryThe Journal of Physical Chemistry B
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Urban MEMS based seismic network for post-earthquakes rapid disaster assessment

2014

Abstract. In this paper, we introduce a project for the realization of the first European real-time urban seismic network based on Micro Electro-Mechanical Systems (MEMS) technology. MEMS accelerometers are a highly enabling technology, and nowadays, the sensitivity and the dynamic range of these sensors are such as to allow the recording of earthquakes of moderate magnitude even at a distance of several tens of kilometers. Moreover, thanks to their low cost and smaller size, MEMS accelerometers can be easily installed in urban areas in order to achieve an urban seismic network constituted by high density of observation points. The network is being implemented in the Acireale Municipality (…

Microelectromechanical systemsSeismic microzonationlcsh:Dynamic and structural geologyComputer scienceSettore GEO/10 - Geofisica Della Terra Solidalcsh:QE1-996.5Magnitude (mathematics)General MedicineDisaster assessmentUrban Seismic Network MEMS Shaking maps Seismic HazardAccelerometerHazardlcsh:Geologylcsh:QE500-639.5Settore GEO/11 - Geofisica ApplicataEarly warning systemlcsh:Qlcsh:ScienceSeismologyVulnerability (computing)
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A novel bio-orthogonal cross-linker for improved protein/protein interaction analysis

2015

International audience; The variety of protein cross-linkers developed in recent years illustrates the current requirement for efficient reagents optimized for mass spectrometry (MS) analysis. To date, the most widely used strategy relies on commercial cross-linkers that bear an isotopically labeled tag and N-hydroxysuccinimid-ester (NHS-ester) moieties. Moreover, an enrichment step using liquid chromatography is usually performed after enzymatic digestion of the cross-linked proteins. Unfortunately, this approach suffers from several limitations. First, it requires large amounts of proteins. Second, NHS-ester cross-linkers are poorly efficient because of their fast hydrolysis in water. Fin…

Models MolecularAzidesMolecular Sequence DataPeptide[CHIM.THER]Chemical Sciences/Medicinal ChemistryMass spectrometry01 natural sciencesMass SpectrometryAnalytical ChemistryProtein–protein interaction03 medical and health sciencesHydrolysis[CHIM.ANAL]Chemical Sciences/Analytical chemistryProtein Interaction MappingHumansOrganic chemistryAmino Acid SequenceProtein Interaction MapsCross linker030304 developmental biologychemistry.chemical_classification0303 health sciencesRigid coreEnzymatic digestionChemistry[CHIM.ORGA]Chemical Sciences/Organic chemistry010401 analytical chemistryHSC70 Heat-Shock ProteinsParkinson Disease[CHIM.CATA]Chemical Sciences/CatalysisCombinatorial chemistry0104 chemical sciences[CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistryCross-Linking ReagentsReagentalpha-SynucleinCarbamates[CHIM.CHEM]Chemical Sciences/CheminformaticsChromatography Liquid
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Receptor-guided 3D-QSAR approach for the discovery of c-kit tyrosine kinase inhibitors

2012

Studies of the the three-dimensional quantitative structure–activity relationships for ninety-five c-kit tyrosine kinase inhibitors were performed. Based on a co-crystallized compound (1 T46), known inhibitors were aligned with c-kit by induced-fit docking, and multiple training/test set splitting was performed to validate the selected pharmacophore model. The best pharmacophore model consisted of five features: one hydrogen-bond donor and four aromatic rings. Reliable statistics were obtained (R 2 = 0.95, R pred 2  = 0.75), and the model was validated by using it to select c-kit inhibitors from a database; 82.1% of the hits it retrieved were active. Accordingly, our model can be reliably u…

Models MolecularQuantitative structure–activity relationshipChemistryStereochemistryOrganic ChemistryQuantitative Structure-Activity RelationshipC-kit . 3D-QSAR . Kohonen maps . Induced-fit dockingSettore CHIM/08 - Chimica FarmaceuticaCatalysisComputer Science ApplicationsInorganic ChemistryProto-Oncogene Proteins c-kitComputational Theory and MathematicsDocking (molecular)Drug DiscoveryPhysical and Theoretical ChemistryPharmacophoreReceptorTyrosine kinaseProtein Kinase Inhibitors
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La questione del confine italo-francese sul Monte Bianco

2020

Even though the common interest of France and Italy in relation to their Alpine border should be enhancing co-operation on cross-border issues (such as improving climate change adaptation as well as preventing and managing risks) a dispute on the delimitation of the border in the area around Monte Bianco has arisen in last years. As any other international dispute on territorial borders, it presents three different plans of analysis: the interpretation of boundary treaties and their official maps; the legal weight of “other” maps; the relationship between the boundary treaty and subsequent practice of the Parties (above all the relevance of effectivités). This article shortly discusses thes…

Mont Blanc International Boundaries Interpretation of Treaties Establishing Boundaries Maps Effectivités Historical Titles Crest of the MountainSettore IUS/13 - Diritto Internazionale
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Application of Precision Agriculture for the Sustainable Management of Fertilization in Olive Groves

2023

Olive tree growing (Olea europaea L.) has considerably increased in the last decades, as has the consumption of extra virgin olive oil in the world. Precision agriculture is increasingly being applied in olive orchards as a new method to manage agronomic variability with the aim of providing individual plants with the right input amount, limiting waste or excess. The objective of this study was to develop a methodology on a GIS platform using GEOBIA algorithms in order to build prescription maps for variable rate (VRT) nitrogen fertilizers application in an olive orchard. The fertilization plan was determined for each tree by applying its own nitrogen balance, taking into account the variab…

NDVISettore AGR/09 - Meccanica Agrariaprecision olive growingGISAgronomy and Crop Scienceprescription mapsAgronomy
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Time-Dependent Density Functional Theory Calculations of N- and S-Doped TiO2 Nanotube for Water-Splitting Applications

2021

This research was funded by the Latvian Council of Science grant LZP-2018/2-0083. Institute of Solid State Physics, University of Latvia, as the Center of Excellence, has received funding from the European Union?s Horizon 2020 Framework Program H2020-WIDESPREAD-01-2016-2017-TeamingPhase2 under Grant Agreement No. 739508, project CAMART2.

NanotubeAnataseMaterials scienceAbsorption spectroscopyabsorption spectraGeneral Chemical Engineering02 engineering and technology7. Clean energy01 natural sciencesTiO2 nanotubeCondensed Matter::Materials Science0103 physical sciencesTime-dependent density functional theoryPhysics::Atomic and Molecular Clusterstransition contribution mapsGeneral Materials ScienceTransition contribution maps010306 general physicsQD1-999TiO<sub>2</sub> nanotubeDopantphotocatalystDopingAbsorption spectraPhotocatalystTime-dependent density functional theory021001 nanoscience & nanotechnologyChemistrytime-dependent density functional theoryChemical physics:NATURAL SCIENCES [Research Subject Categories]Water splittingDensity functional theory0210 nano-technologyNanomaterials
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Navigācijas lietotņu "Google Maps" un "Waze" lietojamības salīdzinājums viedtālruņos

2018

Mūsdienās viedtālruņi ļoti attīstās, līdz ar to, attīstās arī to funkcijas. Viena no tām ir navigācijas lietotnes, bez kurām nav iedomājama mūsdienu cilvēku ikdiena. Bakalaura darba „Navigācijas lietotņu ”Google Maps” un ”Waze” lietojamības salīdzinājums viedtālruņos” mērķis ir izpētīt un raksturot vai cilvēki savā ikdienā izmantojot navigācijas lietotnes spēj novērtēt labas lietojamības principus, kā arī apzinas to sniegtās iespējas un spēj izprast to galvenās atķīrības. Pētījumā tiek apskatīts un par teorētisko pamatu ņemts Mijiedarbības trīs komponentu modelis. Lai veiktu kvalitatīvu pētījumu tiek izmantotas divas pētnecības metodes – verbālais protokols un kvantitatīvā kontentanalīze, a…

Navigācijas lietotnesNovērtējumsWazeGoogle MapsBibliotēkzinātneLietojamība
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Setting up of a technical economic index of priority scales for urban noise control

2005

Correct application of the criteria contained in rules and/or recommendations allows verifying the exposure standards and provides technical directions for actions of protection along acoustically similar areas. Taking into account the compulsory value of the rule and the budget demands, in relation to the complexity of the concerned environmental system (noise sources, physical configuration, exposed people, etc.), an effective implementation of noise control measures can benefit by a procedure for fixing the optimum sequence. This paper we first analyse some priority criteria proposed by some of the authors. A further tool is available using the TEI Technical Economic Index, by the author…

Noise pollutionnoise mapsAcoustic variables control
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Noise in a hospital area. Measure and evaluation

2005

The territory of Sciacca has been acoustically subdivided into homogeneous areas by the authors. In the present job, our attention is focused on the zones in class I that includes particularly sensitive areas as schools and hospitals. The acoustic climate inside and outside the hospital of Sciacca is carried out. The hospital was built on a hillock. Around the hillock two roads, an urban and a main highway are present, both with high traffic. With a campaign of measures, in proximity of the roads, in the hospital square, in the parking, and finally inside the hospital, the equivalent level and the patients exposure was calculated as Ld, Ln and DNL. Both the impact due to the roads (consider…

Noise pollutionnoise mapsAcoustic variables control
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