Search results for " Mark"
showing 10 items of 4118 documents
Sensitivity of liver metabolism in jerboa (Jaculus orientalis) to ciprofibrate, a peroxisome proliferator.
2009
International audience; Ciprofibrate is a well-known drug used to normalize lipid parameters and fibrinogen in atherosclerosis patients. In laboratory rodents such as rats or mice, ciprofibrate exhibits peroxisome proliferator activity. However, to date, no clear alterations or side effects caused by ciprofibrate have been noted in humans. In order to further investigate such possible relationships, we studied the effects of sustained ciprofibrate treatment in jerboas (Jaculus orientalis). In these rodents, ciprofibrate does not induce hepatomegaly or promote liver cell DNA replication, confirming that this species more closely resembles humans than do rats or mice. The jerboas were treated…
Droloxifene-Induced Spikes of Tumor Markers Predict Benefit of Therapy
1991
In the clinical monitoring of cancer, tumor marker proteins may reflect the status of the disease. In cases with radio- and chemotherapy, spikes of tumor markers were found shortly after starting the therapy. These spikes were interpreted as a sign of tumor lysis. Recently during therapy of breast cancer with the new antiestrogen droloxifene, spikes of CA 125 and CA 15-3 were also found in about one-third of patients responding to therapy. The peaks of these initial increases were recorded between 14 and 60 days after the onset of treatment, with maximum concentrations up to 1,890% of the initial value. Marker concentrations decreased thereafter, to new baselines at or below the initial val…
Genome-wide analysis reveals the patterns of genetic diversity and population structure of 8 Italian local chicken breeds
2021
The aim of this study was to conduct a genome-wide comparative analysis of 8 local Italian chicken breeds (Ermellinata di Rovigo, Millefiori di Lonigo [PML], Polverara Bianca, Polverara Nera, Padovana, Pepoi [PPP], Robusta Lionata, and Robusta Maculata), all under a conservation plan, to understand their genetic diversity and population structure. A total of 152 animals were analyzed using the Affymetrix Axiom 600 K Chicken Genotyping Array. The levels of genetic diversity were highest and lowest in PML and PPP, respectively. The results of genomic inbreeding based on runs of homozygosity (ROH; FROH) showed marked differences among breeds and ranged from 0.161 (PML) to 0.478 (PPP). Furtherm…
The analysis of 51 genes in DSM-IV combined type attention deficit hyperactivity disorder: association signals in DRD4, DAT1 and 16 other genes.
2006
Contains fulltext : 35205.pdf (Publisher’s version ) (Closed access) Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder, starting in early childhood and persisting into adulthood in the majority of cases. Family and twin studies have demonstrated the importance of genetic factors and candidate gene association studies have identified several loci that exert small but significant effects on ADHD. To provide further clarification of reported associations and identify novel associated genes, we examined 1,038 single-nucleotide polymorphisms (SNPs) spanning 51 candidate genes involved in the regulation of neurotransmitter pathways, particularly dopamine, nor…
Palermo, stima del canone di affitto di un magazzino con procedimenti market oriented
2009
Stima del canone di mercato secondo gli standard valutativi internazionali
Eiropas investīciju fondu sniegums
2016
Bakalaura darba temats ir " Eiropas investīciju fondu sniegums". Darba izpēta uzņēmumus finansēšanas problēmas ES ietvaros, pēc 2008.g. finanšu krīzes sekām. Tika radīta jauna stratēģija ES līmenī, ar mērķi pāriet uz kapitāla tirgus balstītam finansējumam, nodrošinajot alternatīvu bankām ka vienīgam finansējuma avotam priekš uzņēmumiem. Lai novērtēt ES CMU iniciatīvas perspektīvu, šīs darbs izpēta kopfondu efektivitātes rādītājus, un potenciālu efektivitātes rādītāju starpību, starp fondiem kas ir saistīti ar bankām un neatkarīgiem fondiem, lielākajos akciju tirgos Eirozonā. Darbs sastāv no tris daļām: 1. Pirmā daļa pēta ES banku sistēmas attīstību, to grūtības nodrošinot atbilstošu finansē…
Foreign Direct Investment Drivers in Romania
2013
Foreign Direct Investment (FDI) represents a condition sine qua non for a sustainable development of Romania, taking into consideration the fact that the domestic capital is not enough to assure a positive and significant growth. The present study uses the multiple linear regression to determine the main factors which influence FDI level in Romania. The international reserve and the capital market index BET have a direct and positive impact on the foreign investment flow, while the short, medium and long private and public external debt proved to influence direct, but in a negative way, the FDI.
A Simulation Analysis of the Microstructure of an Order Driven Financial Market with Multiple Securities and Portfolio Choices
2005
In this paper we propose an artificial market where multiple risky assets are exchanged. Agents are constrained by the availability of resources and trade to adjust their portfolio according to an exogenously given target portfolio. We model the trading mechanism as a continuous auction order-driven market. Agents are heterogeneous in terms of desired target portfolio allocations, but they are homogeneous in terms of trading strategies. We investigate the role played by the trading mechanism in affecting the dynamics of prices, trading volume and volatility. We show that the institutional setting of a double auction market is sufficient to generate a non-normal distribution of price changes…
Il cappero: analisi desk sui flussi di commercializzazione in Italia e nei principali Paesi competitors
2009
In questi ultimi anni, il commercio di cappero, a livello internazionale, ha fatto registrare un trend positivo rappresentato da uno scambio di prodotto pari, secondo dati forniti dal COMTRADE, a circa 3 mila tonnellate. A fronte di tali incrementi, in Italia, la superficie investita a cappero è scesa drasticamente, passando da circa 1000 ha nel ’83 a circa 170 ha nel 2006. Ciò, presumibilmente, è dovuto alla carente attuazione di sapienti strategie di marketing sul prodotto cappero da parte degli imprenditori agricoli. In quest’ottica, nell’ambito del progetto “IL CAPPERO DELLE ISOLE MINORI”, è stata avviata una ricerca con lo scopo di elaborare un piano strategico di rilancio del comparto…
What You Should Know About Carbon Markets
2008
Since the entry into force of the Kyoto Protocol, carbon trading has been in continuous expansion. In this paper, we review the origins of carbon trading in order to understand how carbon trading works in Europe and, specifically, the functioning of the European Union Emission Trading Scheme (EU ETS) and the workings of several spot, futures and options markets where European Union Allowances are traded. As well, the linking of the EU ETS with the other United Nations carbon markets is also studied.