Search results for " Max"

Oral paracoccidioidomycosis in a non-endemic region from Brazil: A short case series.

2019

Background Although the paracoccidioidomycosis (PCM) is endemic in Brazil, the occurrence in most states from the North and Northeastern Brazil is very unusual. The aim of this study was to evaluate the clinicopathologic features of a case series of oral PCM in a non-endemic region from Brazil (Northeastern region), discussing the clinical and histopathological differential diagnoses of the oral manifestations of the disease. Material and methods Between 2000 and 2017, all cases of oral PCM were retrieved from the Oral Pathology Laboratory, Universidade Federal de Pernambuco, located at Northeastern Brazil. Clinical data, such as age, gender, origin, occupation, site, symptoms, time of comp…

One repetition maximum bench press performance: A new approach for its evaluation in inexperienced males and females: A pilot study

2014

Summary The aim of this study was to evaluate a new method to perform the one repetition maximum (1RM) bench press test, by combining previously validated predictive and practical procedures. Eight young male and 7 females participants, with no previous experience of resistance training, performed a first set of repetitions to fatigue (RTF) with a workload corresponding to 1/3 of their body mass (BM) for a maximum of 25 repetitions. Following a 5-min recovery period, a second set of RTF was performed with a workload corresponding to 1/2 of participants’ BM. The number of repetitions performed in this set was then used to predict the workload to be used for the 1RM bench press test using May…

Demogenomic modeling of the timing and the processes of early European farmers differentiation

2020

AbstractThe precise genetic origins of the first Neolithic farming populations, as well as the processes and the timing of their differentiation, remain largely unknown. Based on demogenomic modeling of high-quality ancient genomes, we show that the early farmers of Anatolia and Europe emerged from a multiphase mixing of a Near Eastern population with a strongly bottlenecked Western hunter-gatherer population after the Last Glacial Maximum. Moreover, the population branch leading to the first farmers of Europe and Anatolia is characterized by a 2,500-year period of extreme genetic drift during its westward range expansion. Based on these findings, we derive a spatially explicit model of the…

La implicatura en los blogs educativos. Una aproximación pragmática

2015

[ES] La tecnología está multiplicando las formas en que podemos comunicarnos. Desde la aparición de Internet, la construcción del discurso, los géneros discursivos y el lenguaje mismo se han visto afectados por las características de este nuevo modo de comunicarse. Aparecen discursos mixtos que hacen necesarios nuevos enfoques. Así, el estudio de la red desde una perspectiva pragmática ha abarcado diferentes aproximaciones (el género, la caracterización del lenguaje de los textos, etc.); los blogs han sido considerados como una forma de conversación. El presente trabajo estudia los blogs educativos desde el punto de vista de las máximas conversacionales de Grice, y, en particular, las impli…

Polyoxypregnanes as safe, potent, and specific ABCB1-inhibitory pro-drugs to overcome multidrug resistance in cancer chemotherapy in vitro and in vivo

2021

Multidrug resistance (MDR) mediated by ATP binding cassette subfamily B member 1 (ABCB1) is significantly hindering effective cancer chemotherapy. However, currently, no ABCB1-inhibitory drugs have been approved to treat MDR cancer clinically, mainly due to the inhibitor specificity, toxicity, and drug interactions. Here, we reported that three polyoxypregnanes (POPs) as the most abundant constituents of Marsdenia tenacissima (M. tenacissima) were novel ABCB1-modulatory pro-drugs, which underwent intestinal microbiota-mediated biotransformation in vivo to generate active metabolites. The metabolites at non-toxic concentrations restored chemosensitivity in ABCB1-overexpressing cancer cells v…

Transition-Edge Sensors for Particle Induced X-ray Emission Measurements

2013

In this paper we present a new measurement setup, where a transitionedge sensor detector array is used to detect X-rays in particle induced X-ray emission measurements with a 2 MeV proton beam. Transition-edge sensors offer orders of magnitude improvement in energy resolution compared to conventional silicon or germanium detectors, making it possible to recognize spectral lines in materials analysis that have previously been impossible to resolve, and to get chemical information from the elements. Our sensors are cooled to the operation temperature (65 mK) with a cryogen-free adiabatic demagnetization refrigerator, which houses a specially designed X-ray snout that has a vacuum tight window…

5 Effects Of Low-intensity Concentric Combined With Blood Flow Restriction On Achilles Tendon

2014

Introduction Weight training is a useful tool in order to achieve muscular hypertrophy. However, the American College of Sports Medicine (ACSM) recommends intensities of 70% of one repetition maximum (1-RM). Those intensities may not be suitable for everyone because of the high mechanical stresses placed upon the joints [Loenneke, 2012]. Nowadays, it is common to combine low-intensity exercise (20–30% 1-RM) with blood flow restriction (BFR) because of the beneficial effects in increased muscular strength, hypertrophy, localised endurance and cardiorespiratory endurance [Pope, 2013]. Despite there is not many papers about the beneficial of this training, it is know that the tendon suffers so…

Osseotite caricati a due mesi nei settori posteriori del mascellare superiore: controllo a 2 anni di due casi clinici

2003

Aim Acid etched surface implants determine high clinical success rates, but little information is available about early loading in the posterior region of the maxilla, area at risk of failure. The aim of this work is to present two case reports of oral rehabilitation through acid etched surface implants (Osseotite, Implant Innovations - 3i, West Palm Beach, FL) loaded two months after insertion in the posterior maxilla. Materials and methods The success of Osseotite implants was assessed 12 and 24 months after prosthetic loading according to Albrektsson et al. criteria (1986). Results No clinical or radiographic signs of implant failure were observed during the two years follow-up. Conclusi…

Prediction of Maxwell – Stefan diffusion coefficients in polymer – multicomponent fluid systems

2014

Abstract Calculations of mass fluxes in multicomponent fluids based on the system of generalized Maxwell–Stefan equations (GMSE) is preferably used because Maxwell–Stefan (M–S) diffusion coefficients are symmetrical and have a clear physical meaning, as they reflect the binary friction forces between compounds in the system. For the calculation of the mass transport of a multicomponent fluid in the polymer basing on GMSE, it is necessary to have M–S diffusion coefficients. This paper proposes a method that allows their calculation using widely available self-diffusion coefficients and binary diffusion coefficients for infinitely diluted mixtures. The proposed method was compared with the me…

2017

Creatine kinase (CK) is a marker for muscle cell damage with limited potential as marker for training load in strength training. Recent exercise studies identified cell free DNA (cfDNA) as a marker for aseptic inflammation and cell damage. Here we overserved in a pilot study the acute effects during strength exercise and chronic effects of regular strength training on cfDNA concentrations over a period of four weeks in three training groups applying conservation training (CT) at 60% of the 1 repetition maximum, high intensity-low repetition training (HT) at 90% of the 1 repetition maximum and differential training (DT) at 60% of the 1 repetition maximum. EDTA-plasma samples were collected b…