Search results for " Middle"

Santi, apostoli e patroni. Storie di agiografia e di potere nell’Inghilterra anglosassone

2018

L’agiografia è un potente veicolo di propaganda e i testi agiografici medievali forniscono una chiave di lettura anche riguardo ai temi dell’etnia e dell’identità dei popoli germanici. Per quanto riguarda il mondo germanico riveste particolare rilievo il culto di quei santi che appaiono più strettamente legati alle formazioni politiche che vanno emergendo in Europa occidentale. Si tratta di culti sostenuti dalle autorità non solo ecclesiastiche ma anche e soprattutto civili, dai sovrani e dai loro entourage. Non si tratta in ogni caso di movimenti prodromici alla affermazione di culti sovraregionali o all’introduzione del concetto di patrono nel senso pieno del termine. I casi presi in esam…

Straining at work and its relationship with personality profiles and individual consequences in healthcare workers (HCWs)

2020

Straining is an attenuated form of mobbing, in which the continuity of vexatious actions is not driven by a discriminatory intent. With the objective of testing the possible moderating role of personality in the relationship between perceptions about straining at work and individual consequences, a correlational design research involved 374 healthcare workers (HCWs) from two Italian hospitals. The following questionnaires were administered: (1) Short Negative Acts Questionnaire (S-NAQ), to assess discriminative actions at work)

Gender differences in chronic liver diseases in two cohorts of 2001 and 2014 in Italy

2017

Background: Gender differences in chronic liver disease (CLD) have been partially investigated. To extend the present knowledge, we evaluated 12,263 patients with CLD enrolled in two national surveys (9997 in 2001 and 2557 in 2014). Methods: The two surveys prospectively recruited patients aged ≥ 18 referring to Italian liver units throughout the country using a similar clinical approach and analytical methods. Results: The overall male to female ratio (M/F) was 1.4 (7138/5124). Compared with females, males were significantly more likely to be younger (52.9 vs. 58.7 yrs.), with HBV infection alone (13.2% vs. 9.2%) and with alcoholic liver disease alone (11.4% vs. 6.9%), but less likely t…

Seguidors vencen, un grito de guerra para un rey: Un lema para la virtud de la Fortaleza en Alfonso V el Magnánimo (1423-1458)

2017

espanolLa historia politica de Alfonso V el Magnanimo, Rey de Aragon (1416-1458) permanece asociada, indefectiblemente, a sus derechos sobre el trono de Napoles. Las vicisitudes que vivio desde 1423, cuando Juana II Durazzo lo destituyo como heredero del mismo, hasta lograrlo en 1442, motivaron toda una serie de elementos representativos con los que el soberano busco legitimarse ante sus subditos y contemporaneos. De entre ellos, reclama la atencion el posible uso que el monarca hizo del lema “Seguidors vencen”. El estudio de dicho mote y su posible asociacion al emblema real del Siti Perillos constituyen el objeto del presente articulo. EnglishThe political history of Alfonsus V the Magnan…

Safety profile of the interleukin-1 inhibitors anakinra and canakinumab in real life clinical practice: a nationwide multicenter retrospective observ…

2018

A few studies have reported the safety profile of interleukin (IL)-1 blockers from real life. The aim of this study is to describe anakinra (ANA) and canakinumab (CAN) safety profile in children and adults, based on data from a real-life setting. Demographic, clinical, and therapeutic data from patients treated with ANA and CAN were retrospectively collected and analyzed. Four hundred and seventy five patients were enrolled; ANA and CAN were prescribed in 421 and 105 treatment courses, respectively. During a mean follow-up of 24.39 ± 27.04 months, 89 adverse events (AE) were recorded; 13 (14.61%) were classified as serious AE (sAE). The overall estimated rate of AE and sAE was 8.4 per 100 p…

FISSIT (Fistula Surgery in Italy) study: A retrospective survey on the surgical management of anal fistulas in Italy over the last 15 years

2021

Background: Surgical treatment of anal fistulas is still a challenge. The aims of this study were to evaluate the adoption and healing rates for the different surgical techniques used in Italy over the past 15 years. Methods: This was a multicenter retrospective observational study of patients affected by simple and complex anal fistulas of cryptoglandular origin who were surgically treated in the period 2003–2017. Surgical techniques were grouped as sphincter-cutting or sphincter-sparing and as technology-assisted or techno-free. All patients included in the study were followed for at least 12 months. Results: A total of 9,536 patients (5,520 simple; 4,016 complex fistulas) entered the stu…

Efficacy of epidural anesthesia for retroperitoneoscopic renal biopsy

2000

Laparoscopic procedures are performed using general anesthesia due to the perceived limitations of regional anesthesia in the upper abdomen and retroperitoneum. We present our initial experience with epidural anesthesia for retroperitoneal laparoscopic renal biopsy.

Low dosage liposomal amphotericin B in the treatment of Candida infections in critically ill patients.

2011

The HCV Sicily Network: A web-based model for the management of HCV chronic liver diseases

2016

Epidemiological studies report that in Sicily reside about 30,000 citizens with a diagnosis of chronic hepatitis due to HCV. The availability of direct antiviral action (DAA) is a real therapeutic breakthrough, but the high cost of the therapeutic regimes limits their use and forced the National Health System to establish clinical priority for the treatment.The HCV Sicily Network is a web-based model of best medical practice, which was designed to improve the management and the treatment of HCV chronic hepatitis and cirrhosis. The network includes 41 centers and 84 gastroenterologists or infectivologists connected by a web platform that recorder the diagnosis and the clinic priority for the…

Focus on the unique mechanisms involved in thoracic aortic aneurysm formation in bicuspid aortic valve versus tricuspid aortic valve patients: clinic…

2013

OBJECTIVES: The involvement of different factors in the onset of thoracic aortic aneurysm (TAA) in patients with a bicuspid aortic valve (BAV) vs those with a tricuspid aortic valve (TAV) is well recognized. However, the molecular, genetic and cellular mechanisms driving TAA remain unclear. The aim of this study was to identify the different mechanisms involved in TAA development in patients with BAV vs TAV. METHODS: Aorta specimens and DNA samples were collected from 24 BAV (18 men and 6 women; mean age: 54.2 ± 14.39 years) and 110 TAV (79 men and 31 women, mean age: 66 ± 9.8 years) patients. A control group of 128 subjects (61 men and 67 woman, mean age: 61.1 ± 5.8 years) was also enrolle…