Search results for " Molecular"

showing 10 items of 14045 documents

A Novel Pathophysiological Mechanism Contributing to Trigeminal Neuralgia

2016

Trigeminal neuralgia (TN) is a form of neuropathic pain that affects the fifth cranial nerve, the most widely distributed nerve in the head. Although TN has been associated with a variety of pathological conditions, neurovascular compression on the trigeminal nerve, as it exits the brain stem, is the most frequent reported cause. This compression provides a progressive demyelination of the nerve and a subsequent aberrant neural transmission. Although several studies have clarified some physiopathological mechanisms underlying TN, the molecular basis remains vague. Very recently the substitution of methionine 136 by valine (MET126Val) in sodium channel Nav1.6 in a case study of typical TN ha…

trigeminal ganglionlcsh:Biochemistry03 medical and health sciencesTrigeminal ganglion0302 clinical medicineaction potentialTrigeminal neuralgianeurovascualr compressionGeneticsmedicinelcsh:QD415-436Molecular BiologyPathologicalTrigeminal neuralgia; action potential; molecular mechanism; neurovascualr compression; trigeminal ganglionGenetics (clinical)Trigeminal nervebusiness.industrySodium channellcsh:RM1-950medicine.diseasePathophysiologylcsh:Therapeutics. Pharmacology030220 oncology & carcinogenesisAnesthesiaNeuropathic painMolecular MedicineBrainstemmolecular mechanismbusinessNeuroscience030217 neurology & neurosurgeryTrigeminal neuralgiaResearch Article
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High-Sensitivity Whispering Gallery Mode Humidity Sensor Based on Glycerol Microdroplet Volumetric Expansion

2021

We demonstrate a highly sensitive whispering gallery mode (WGM) relative humidity (RH) sensor based on a glycerol microdroplet. WGMs were excited using a 760 nm tunable semiconductor laser. We used free space coupling, which is effective when using a liquid resonator. A detailed analysis of different parameters influencing the sensor’s characteristics (sensitivity, hysteresis, resolution, stability, and temperature) is presented. The sensitivity of the sensor is one of the highest reported (2.85 nm/% RH in the range 50–70% RH with the resolution 1 × 10−4% RH). This type of humidity sensor has several advantages, such as high sensitivity, extended lifetime, good repeatability, and low cost, …

tunable laserMaterials science02 engineering and technologyglycerollcsh:Chemical technology01 natural sciencesBiochemistryArticleAnalytical Chemistrylaw.invention010309 opticsResonatorlaw0103 physical sciencesRelative humiditylcsh:TP1-1185Sensitivity (control systems)humidity sensorElectrical and Electronic EngineeringInstrumentationbusiness.industryHumidity021001 nanoscience & nanotechnologyLaserAtomic and Molecular Physics and OpticsSemiconductorOptoelectronicsWhispering-gallery wave0210 nano-technologybusinessmicrosphere resonatorTunable laserwhispering gallery modeSensors
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Understanding tungsten erosion during inter/intra-ELM periods in He-dominated JET-ILW plasmas

2021

Tungsten erosion was quantified during inter/intra-ELM periods in He-dominated JET-ILW plasmas by optical emission spectroscopy. The intra-ELM tungsten sputtering in helium plasmas, which dominates the total W source, prevails by a factor of about 4 over inter-ELM sputtering in the investigated ELM frequency range from 90 Hz-120 Hz. He ions are mainly responsible for the W erosion during the ELMs in He plasmas. The strong in/out asymmetry of the ELM-induced W erosion is observed in He plasmas even at high ELM frequencies beyond 100 Hz. In Ohmic/L-mode plasmas and during the H-mode inter-ELM plasma phases both He2+ and Be2+ ionic species are major contributors to the W erosion. Their contrib…

tungsten divertorJet (fluid)Materials scienceJET-ILWchemistry.chemical_elementMechanicsPlasmaTungstenCondensed Matter PhysicsAtomic and Molecular Physics and Opticsoptical emission spectroscopyplasma-material interactionshelium plasmachemistryErosionddc:530tungsten erosionMathematical Physics
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Mecanismo molecular del proceso de ubicuitinación mediado por el complejo laforina-malina.

2017

Tesis doctoral, 123 páginas.

ubicuitinaUNESCO::CIENCIAS DE LA VIDAfosfatasasLaforamitofagia:CIENCIAS DE LA VIDA [UNESCO]biología molecularautofagia
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A Computationally Efficient Online/Offline Signature Scheme for Underwater Wireless Sensor Networks

2022

Underwater wireless sensor networks (UWSNs) have emerged as the most widely used wireless network infrastructure in many applications. Sensing nodes are frequently deployed in hostile aquatic environments in order to collect data on resources that are severely limited in terms of transmission time and bandwidth. Since underwater information is very sensitive and unique, the authentication of users is very important to access the data and information. UWSNs have unique communication and computation needs that are not met by the existing digital signature techniques. As a result, a lightweight signature scheme is required to meet the communication and computation requirements. In this researc…

underwater wireless sensor networks; certificateless online/offline signature; authentication schemeElectrical and Electronic EngineeringVDP::Teknologi: 500::Informasjons- og kommunikasjonsteknologi: 550BiochemistryInstrumentationAtomic and Molecular Physics and OpticsAnalytical ChemistrySensors
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A new forum for upconversion research: The UPCON conference

2019

International audience; The Conference and Spring School on Properties, Design and Applications of Upconversion Nanomaterials (UPCON) provides a new forum for all experts and newcomers in the field of upconversion research. On the occasion of the second UPCON 2018 in Valencia (Spain), we are pleased to present a collection of 12 reviews and research articles that reflect recent advances in upconversion materials, their unique luminescent properties and many applications spanning from nanoscale thermometry to biomedicine.

upconversionEngineeringbusiness.industry[SDV]Life Sciences [q-bio]02 engineering and technology010402 general chemistry021001 nanoscience & nanotechnologybackground-free01 natural sciencesEngineering physicsAtomic and Molecular Physics and OpticsPhoton upconversion0104 chemical sciencesluminescenceGeneral Materials Science0210 nano-technologybusinessInstrumentationSpectroscopynanomaterials
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Creating Implicit Measure Stimulus Sets Using a Multi-Step Piloting Method

2023

The effect of arbitrary stimulus selection is a persistent concern when employing implicit measures. The current study tests a data-driven multi-step procedure to create stimulus items using a combination of free-recall and survey data. Six sets of stimulus items were created, representing healthy food and high sugar items in children, adolescents, and adults. Selected items were highly representative of the target concepts, in frequent use, and of near equal length. Tests of the piloted items in two samples showed slightly higher implicit measure–behavior relations compared to a previously used measure, providing preliminary support for the value in empirically based stimulus selection. Fu…

valintavertailuimplicit attitudeStructural Biologyimplicit measureskuluttajakäyttäytyminenimplicit association testimplicit measures; implicit attitude; implicit association testBiochemistry Genetics and Molecular Biology (miscellaneous)BiotechnologyMethods and Protocols; Volume 6; Issue 3; Pages: 47
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CYGD: the Comprehensive Yeast Genome Database.

2005

The comprehensive resource is available under http://mips.gsf.de/genre/proj/yeast/.; International audience; The Comprehensive Yeast Genome Database (CYGD) compiles a comprehensive data resource for information on the cellular functions of the yeast Saccharomyces cerevisiae and related species, chosen as the best understood model organism for eukaryotes. The database serves as a common resource generated by a European consortium, going beyond the provision of sequence information and functional annotations on individual genes and proteins. In addition, it provides information on the physical and functional interactions among proteins as well as other genetic elements. These cellular network…

ved/biology.organism_classification_rank.speciesSACCHAROMYCES CEREVISIAE GENOME;COMPREHENSIVE YEAST GENOME DATABASE;CYGD;PROTEIN INTERACTION;EUROPEAN CONSORTIUM;SEQUENCE INFORMATION;YEAST GENOME;SEQUENCED EUKARYOTIC GENOMEcomputer.software_genreGenomeSaccharomycesUser-Computer InterfaceSequence Analysis ProteinDatabases GeneticYEAST GENOME[INFO.INFO-BI] Computer Science [cs]/Bioinformatics [q-bio.QM]0303 health sciences[SDV.BIBS] Life Sciences [q-bio]/Quantitative Methods [q-bio.QM]biologyDatabase030302 biochemistry & molecular biologyEUROPEAN CONSORTIUMArticlesGenomicsCYGD[SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM]PROTEIN INTERACTIONSEQUENCED EUKARYOTIC GENOMEnucleic acidsCOMPREHENSIVE YEAST GENOME DATABASEBio-informatiqueGenome FungalSEQUENCE INFORMATIONSaccharomyces cerevisiae ProteinsBioinformaticsSaccharomyces cerevisiae610Saccharomyces cerevisiaeGenètica molecularSACCHAROMYCES CEREVISIAE GENOMESaccharomyces03 medical and health sciencesAnnotationGeneticsSIMAPModel organismGene030304 developmental biologyBinding Sitesved/biologyMembrane ProteinsMembrane Transport Proteinsbiology.organism_classificationYeast[INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM]computerSDV:BIBSTranscription Factors
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Molecular and functional approaches to understand the natural history of snake short disintegrins

2016

211 páginas, figuras y tablas

venenos de serpientesUNESCO::CIENCIAS MÉDICASUNESCO::CIENCIAS DE LA VIDAdisintegrinasproteinas recombinantes:CIENCIAS MÉDICAS [UNESCO]biología molecular:CIENCIAS DE LA VIDA [UNESCO]comportamiento de serpientes
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Advances in Wine Fermentation

2021

Fermentation is a well-known natural process that has been used by humanity for thousands of years, with the fundamental purpose of making alcoholic beverages such as wine, and also other non-alcoholic products. From a strictly biochemical point of view, fermentation is a process of central metabolism in which an organism converts a carbohydrate, such as starch or sugar, into an alcohol or an acid. The fermentation process turns grape juice (must) into wine. This is a complex chemical reaction whereby the yeast interacts with the sugars (glucose and fructose) in the must to create ethanol and carbon dioxide. Fermentation processes to produce wines are traditionally carried out with Saccharo…

vesselsFermentation industries. Beverages. AlcoholyeastsPlant ScienceBiochemistry Genetics and Molecular Biology (miscellaneous)chemistry.chemical_compoundFermentacióFood sciencewineSugarfermentationWineFermentation in winemakingTP500-660EthanolChemistryfood and beveragesFructoseYeastLactic acidcarbohydrates (lipids)lactic acid bacteriaViniculturaFermentationmicro-oxygenationFood ScienceFermentation
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