Search results for " Movement"
showing 10 items of 1376 documents
CONSIDERATIONS REGARDING REGULATIONS ON FINANCIAL MARKETS IN THE CONDITIONS OF ROMANIA AS A EU MEMBER STATE
2018
Financial markets are increasingly becoming an area of major interest to the European Union in its efforts to achieve competitive global development levels similar to those of the United States. The Lisbon Agenda is a testimony to this, although the latest assessments are not at all optimistic about the achievement of the target as expected for 2010. To meet its objectives, the EU has generated a comprehensive package of regulatory initiatives, composed of directives and regulations that translate its policies into the field. The paper aims at a careful review of all of them. Approximation of investment and capital markets is made from the two major chapters of Community policies whose free…
Azithromycin Differentially Alters TCR-Activated Helper T Cell Subset Phenotype and Effector Function
2020
In addition to their antibiotic activities, azithromycin (AZM) exhibits anti-inflammatory effects in various respiratory diseases. One of the potent anti-inflammatory mechanisms is through inhibition of CD4+ helper T (Th) cell effector function. However, their impact on specific Th subset is obscure. Herein, we demonstrate the cellular basis of phenotypic and functional alterations associated with Th subsets following AZM treatment in vitro. Using well-characterized Th subset specific chemokine receptors, we report significant suppression of T cell receptor (TCR)-stimulated hyperactivated CCR4+CXCR3+ (Th0) expansion compared to CCR4-CXCR3+ (Th1-like) and CCR4+CXCR3- (Th2-like) cells. Intere…
Neutrophils: Between host defence, immune modulation, and tissue injury.
2015
Neutrophils, the most abundant human immune cells, are rapidly recruited to sites of infection, where they fulfill their life-saving antimicrobial functions. While traditionally regarded as short-lived phagocytes, recent findings on long-term survival, neutrophil extracellular trap (NET) formation, heterogeneity and plasticity, suppressive functions, and tissue injury have expanded our understanding of their diverse role in infection and inflammation. This review summarises our current understanding of neutrophils in host-pathogen interactions and disease involvement, illustrating the versatility and plasticity of the neutrophil, moving between host defence, immune modulation, and tissue da…
B lymphocyte intestinal homing in inflammatory bowel disease.
2011
Abstract Background Inflammatory bowel disease (IBD) is thought to be due to an abnormal interaction between the host immune system and commensal microflora. Within the intestinal immune system, B cells produce physiologically natural antibodies but pathologically atypical anti-neutrophil antibodies (xANCAs) are frequently observed in patients with IBD. The objective is to investigate the localisation of immunoglobulin-producing cells (IPCs) in samples of inflamed intestinal tissue taken from patients with IBD, and their possible relationship with clinical features. Methods The IPCs in small intestinal, colonic and rectal biopsy specimens of patients with IBD were analysed by means of immun…
Leukotriene B4-loaded microspheres: a new therapeutic strategy to modulate cell activation
2008
AbstractBackgroundLeukotriene B4(LTB4) is a potent inflammatory mediator that also stimulates the immune response. In addition, it promotes polymorphonuclear leukocyte phagocytosis, chemotaxis, chemokinesis and modulates cytokines release. Regarding chemical instability of the leukotriene molecule, in the present study we assessed the immunomodulatory activities conferred by LTB4released from microspheres (MS). A previous oil-in-water emulsion solvent extraction-evaporation method was chosen to prepare LTB4-loaded MS.ResultsIn the mice cremasteric microcirculation, intraescrotal injection of 0.1 ml of LTB4-loaded MS provoked significant increases in leukocyte rolling flux, adhesion and emig…
Defectivitat morfològica i variació sintàctica
2021
This paper discusses a case of parametric variation between Catalan and Spanish that concerns the fronting possibilities within the CP domain (the so-called ÇLeft PeripheryÈ). In particular, attention is paid to Catalan’s weak left peripheral activity, which prevents it from generating sentences that involve a Çmild focalizationÈ pattern very common in Spanish (e.g., «Mucha tontería dice el Gobierno» vs. *«Molta ximpleria diuel Govern»), first noted by Torrego (1980) and further explored by Uriagereka (1988). Interestingly, the same behavior is observed in the v*P domain, which accounts for the fact that VSO sentences (generated through movement of the subject to a specifier position, as Or…
Might as well jump: Sound affects muscle activation in skateboarding
2014
The aim of the study is to reveal the role of sound in action anticipation and performance, and to test whether the level of precision in action planning and execution is related to the level of sensorimotor skills and experience that listeners possess about a specific action. Individuals ranging from 18 to 75 years of age - some of them without any skills in skateboarding and others experts in this sport - were compared in their ability to anticipate and simulate a skateboarding jump by listening to the sound it produces. Only skaters were able to modulate the forces underfoot and to apply muscle synergies that closely resembled the ones that a skater would use if actually jumping on a ska…
Antimafia e movimenti delle donne. Protagoniste, culture, linguaggi
2016
Il saggio analizza il ruolo giocato dalle donne nei movimenti antimafia a partire dalla loro presenza –cospicua e importante – all’interno dei Fasci dei lavoratori in Sicilia alla fine dell’800 fino alle esperienze del Comitato dei Lenzuoli e dell’Associazione donne per il digiuno nate a Palermo all’indomani delle stragi di Capaci e di via D’Amelio, in cui le figure femminili hanno svolto un ruolo di primo piano sperimentando forme espressive e di mobilitazione civile alternative ed efficaci. L’approccio scelto per l’analisi incrocia gli studi sulla mafia come sistema di potere violento e totalitario con la relazione tra i sessi, intesa come scontro di poteri, in cui svolge un peso determin…
Investigating the direct and indirect effects of a school-based leadership program for primary school students: Rationale and study protocol for the …
2023
Background Leadership is a valuable skill that can be taught in school, and which may have benefits within and beyond the classroom. Learning to Lead (L2L) is a student-led, primary school-based leadership program whereby older ‘peer leaders’ deliver a fundamental movement skills (FMS) program to younger ‘peers’ within their own school. Aim The aims of the study are to determine the efficacy of a peer-led FMS intervention on: (i) peer leaders’ (aged 10 to 12 years) leadership effectiveness (primary outcome), leadership self-efficacy, well-being, and time on-task in the classroom; (ii) peers’ (aged 8 to 10 years) physical activity levels, actual and perceived FMS competency, cardiorespirato…
Perceptions of learning and teaching human movement in physiotherapy : A systematic review and metasynthesis of qualitative studies
2023
Purpose: Human movement is essential for health and well-being. Understanding human movement is pivotal in physiotherapy, but also an important element of physiotherapy education. This review identified, critically appraised, and synthesized the available evidence on learning and teaching human movement in physiotherapy as perceived by students, therapists, and instructors. Methods: The databases MEDLINE, CINAHL, ERIC, PsycINFO, MEDIC and FINNA, were searched. The search was conducted in March/April 2020 and updated in March 2022. The systematic review followed the JBI methodology for systematic reviews of qualitative evidence and was conducted in accordance with an a priori protocol. Resul…