Search results for " Need"
showing 10 items of 648 documents
Bortezomib induction, reduced-intensity transplantation, and lenalidomide consolidation-maintenance for myeloma: updated results.
2013
A sequential approach including bortezomib induction, intermediate-dose melphalan, and autologous stem cell transplantation (ASCT), followed by lenalidomide consolidation-maintenance, has been evaluated. Efficacy and safety data have been analyzed on intention-to-treat and results updated. Newly diagnosed myeloma patients 65 to 75 years of age (n = 102) received 4 cycles of bortezomib-pegylated liposomal doxorubicin-dexamethasone, tandem melphalan (100 mg/m(2)) followed by ASCT (MEL100-ASCT), 4 cycles of lenalidomide-prednisone consolidation (LP), and lenalidomide maintenance (L) until disease progression. The complete response (CR) rate was 33% after MEL100-ASCT, 48% after LP and 53% after…
Biology and significance of alpha‐fetoprotein in hepatocellular carcinoma
2019
Hepatocellular carcinoma (HCC) is one of the most common causes of cancer-related deaths globally due, in part, to the majority of patients being diagnosed with intermediate or advanced stage disease. Our increased understanding of the heterogeneous molecular pathogenesis of HCC has led to significant developments in novel targeted therapies. Despite these advances, there remains a high unmet need for new treatment options. HCC is a complex disease with multiple pathogenic mechanisms caused by a variety of risk factors, making it difficult to characterize with a single biomarker. In fact, numerous biomarkers have been studied in HCC, but alpha-fetoprotein (AFP) remains the most widely used …
Oral health-related quality of life after dental treatment in patients with intellectual disability
2020
Background The influence of dental treatment on oral health-related quality of life (OHRQOL) has rarely been evaluated in patients with intellectual disability (ID) through validated questionnaires. The aim of this study was to estimate the changes on OHRQOL in patients with ID after the implementation of an institutional dental treatment program under general anesthesia using the Franciscan Hospital for Children Oral Health-Related Quality of Life questionnaire (FHCOHRQOL-Q). Material and Methods A prospective longitudinal study was conducted on 85 patients (mean age=24.85 years) classified according to DSM-V whose parents/caregivers completed the FHC-OHRQOL-Q. We analyzed the changes in t…
Thoureau, Wright e il guscio della tartaruga. La questione della mimesi nell’organicismo digitale e le sue implicazioni teoriche
2020
This paper deals with the complex relationship between the observation of nature and the development of digital- design processes. This relationship reveals itself aporetic particularly if the concept of mimesis has been clarified. This contribution focuses on some projects that may be ascribed in digital organicism. Challenged by the observation of “The Elephant house” by Markus Schietsch Architekten in Zurich, the paper refers to some fundamental texts that show how an explicit and structured theory may help to avoid a new sublimation of the technique through miming natural forms.
Compensating Need Satisfaction across Life Boundaries: A Daily Diary Study
2017
Self-determination theory suggests that satisfaction of an individual's basic psychological needs (for competence, autonomy, and relatedness) is a key for well-being. This has gained empirical support in multiple life domains, but little is known about the way that need satisfaction interacts between work and home. Drawing from ideas of work–home compensation, we expect that the benefits of need satisfaction in the home domain are reduced when needs are satisfied in the work domain. We tested this hypothesis with a daily diary study involving 91 workers. Results showed that individuals particularly benefit from satisfaction of their need for competence in the home domain when it is not sati…
Astronomical Activities with Disabled People
2010
With this contribution we would like to share our experiences in organizing astronomical activities addressed to people with disabilities. The goal is twofold: we would like to invite all those with similar experiences to contribute to the compilation of a document to guide other astronomers who might be interested in carrying out these kind of activities aimed at groups of people with special needs. We also want to persuade public outreach officers that working with disabled people is not as difficult as it may seem at first, as long as they are provided with adequate educational material and guidelines about how to do it. The final goal is to build a repository that can be used by educato…
Derecho de los hijos nacidos por reproducción asistida a conocer la identidad de sus padres biológicos: Breves reflexiones y propuestas
2018
The present communication intends to analyze and reflect on the existing problem and the conflict of rights produced regarding the need of information of a son to know the identity of his biological parents, possible discrimination by birth. Comparative law. Analysis of the right to personal and family privacy, and right to Identity. Consideration of public information as an essential element of the practice of techniques
Reliability of grading preoperative pancreatic neuroendocrine tumors on EUS specimens: a systematic review with meta-analysis of aggregate and indivi…
2022
Background and aims: Therapy and prognosis of pancreatic neuroendocrine tumors (PanNETs) are strictly related to the Ki-67 index, which defines tumor grading. The criterion standard for the assessment of grading of PanNETs is EUS-guided FNA (EUS-FBAFNA) or EUS-guided fine-needle biopsy sampling (EUS-FNB). Because data on diagnostic accuracy of EUS-FNA and EUS-FNB are heterogeneous, we aimed to analyze the variability in concordance between EUS grading and surgical grading. Methods: The MEDLINE, SCOPUS, and EMBASE databases were searched until November 2021 to identify studies reporting the concordance rate between EUS grading and surgical grading. The study was conducted in accordance with …
Abstract – Using Parallel Corpora for Translation Activities in L2 Medical English Undergraduate Teaching, with Specific Reference to Italian Sports …
2021
English is the international language of science and, as such, it is also the international language of medicine. L2 English undergraduates do not generally have particular difficulties in translating from English into their mother tongue; by contrast, they do not perform very well when asked to translate into English. The aim of this report is to show the results of a study obtained by using parallel corpora in scientific English classes in the Italian sports sciences study course of the University of Palermo. The students were provided with a corpus of English texts taken from a well-known medical text with pedagogical purposes, and their corresponding Italian translations, which were car…
Using Parallel Corpora for Translation Activities in L2 Medical English Undergraduate Teaching, with Specific Reference to Italian Sports Sciences Co…
2021
English is the international language of science and, as such, it is also the international language of medicine. L2 English undergraduates do not generally have particular difficulties in translating from English into their mother tongue; by contrast, they do not perform very well when asked to translate into English. The aim of this report is to show the results of a study obtained by using parallel corpora in scientific English classes in the Italian sports sciences study course of the University of Palermo. The students were provided with a corpus of English texts taken from a well-known medical text with pedagogical purposes, and their corresponding Italian translations, which were car…