Search results for " OPT"

showing 10 items of 13620 documents

Lentes de contato corneoesclerais adaptadas em córneas irregulares após cirurgia LASIK

2018

ABSTRACT Purpose: We aimed to describe the outcomes of corneoscleral contact lens fitting with multi-aspherical geometry designs in patients with irregular corneas after laser-assisted in situ keratomileusis (LASIK). Methods: This was a retrospective series of 18 patients (age, 26-38 years) selected from an eye clinic database. Participants were required to have unsatisfactory visual acuity with their current contact lenses or spectacles after LASIK for myopia correction. All patients were fitted with corneoscleral contact lenses designed to correct corneal surface irregularities. A diagnostic trial set was used for fitting, and assessments were performed according to a standardized methodo…

AdultCorneal surgery laserIntraocular pressuremedicine.medical_specialtyCorneal Wavefront AberrationVisual acuityPaquimetria corneanagenetic structuresIntraocular pressuremedicine.medical_treatmentKeratomileusis Laser In SituVisual AcuityLentes de contatoKeratomileusisCorneal endothelial cell losslaw.invention03 medical and health sciencesCorneal pachymetry0302 clinical medicinePerda de células endoteliais da córneaPressão intraocularlcsh:OphthalmologylawOphthalmologyMyopiaHumansMedicineContact lensesCorneal pachymetryCirurgia da córnea a laserRetrospective Studiesmedicine.diagnostic_testbusiness.industryCorneal TopographyLASIKGeneral MedicineContact Lenses HydrophilicCorneal topographyeye diseasesLens (optics)Contact lensOphthalmologylcsh:RE1-994030221 ophthalmology & optometrysense organsmedicine.symptombusiness030217 neurology & neurosurgeryFollow-Up Studies
researchProduct

Visual simulation through different intraocular lenses using adaptive optics: Effect of tilt and decentration

2011

Purpose To analyze visual quality differences between intraocular lenses (IOLs) and assess the impact of IOL decentration and tilt on visual quality. Setting University of Valencia, Valencia, Spain. Design Cohort study. Methods The crx1 adaptive optics visual simulator was used to simulate the wavefront aberration pattern of 2 commercially available aspheric aberration-correcting IOLs (Acrysof IQ SN60WF and Tecnis ZA9003) and 2 spherical IOLs (Akreos Adapt and Triplato) in 5 situations: centered, decentered 0.2 mm and 0.4 mm, and tilted 2 degrees and 4 degrees. Monocular distance visual acuity at 100%, 50%, and 10% contrast and the depth of focus were measured. Results Ten eyes of 10 patien…

AdultDepth of focusCorneal Wavefront AberrationVisual acuityPseudophakiagenetic structuresmedia_common.quotation_subjectVisual AcuityArtificial Lens Implant MigrationCohort StudiesYoung AdultAberrometryPsychophysicsmedicineHumansContrast (vision)Adaptive opticsmedia_commonMathematicsLenses IntraocularDepth PerceptionMonocularAberrometryModels Theoreticalequipment and supplieseye diseasesSensory SystemsOphthalmologySpherical aberrationTilt (optics)OptometrySurgerysense organsmedicine.symptomJournal of Cataract and Refractive Surgery
researchProduct

Simulated prototype of posterior chamber phakic intraocular lens for presbyopia correction.

2014

Purpose To evaluate the visual impact of adding different spherical aberration values to an Implantable Collamer Lens phakic intraocular lens (pIOL) to increase the depth of focus using an adaptive optics visual simulator. Setting University of Valencia, Valencia, Spain. Design Experimental study. Methods Wavefront aberrations in −3.00 D and −6.00 diopter (D) pIOLs were measured in vitro. Afterward, different simulated pIOL experimental prototypes were created along with variances in the spherical aberration. An adaptive optics visual simulator was used to simulate vision after the implantation of the different pIOL prototypes from their wavefront aberrations. The corrected distance visual …

AdultDepth of focusPhakic Intraocular LensesVisual acuityCorneal Wavefront Aberrationgenetic structuresVisual AcuityDiagnostic Techniques OphthalmologicalPhakic intraocular lensProsthesis DesignYoung AdultLens Implantation IntraocularmedicineHumansComputer SimulationAdaptive opticsDioptreMathematicsWavefrontDepth PerceptionPupilPresbyopiaPresbyopiamedicine.diseaseeye diseasesSensory SystemsOphthalmologySpherical aberrationOptometrySurgerysense organsmedicine.symptomJournal of cataract and refractive surgery
researchProduct

Noncontact monitoring of vascular lesion phototherapy efficiency by RGB multispectral imaging.

2013

A prototype low-cost RGB imaging system consisting of a commercial RGB CMOS sensor, RGB light-emitting diode ring light illuminator, and a set of polarizers was designed and tested for mapping the skin erythema index, in order to monitor skin recovery after phototherapy of vascular lesions, such as hemangiomas and telangiectasias. The contrast of erythema index (CEI) was proposed as a parameter for quantitative characterization of vascular lesions. Skin recovery was characterized as a decrease of the CEI value relative to the value before the treatment. This approach was clinically validated by examining 31 vascular lesions before and after phototherapy.

AdultDiagnostic ImagingSkin erythemaPathologymedicine.medical_specialtyErythemaMultispectral imageBiomedical EngineeringBiomaterialsYoung AdultMedicineHumansTelangiectasisSkinCMOS sensorintegumentary systembusiness.industrySpectrum AnalysisVascular lesionMiddle AgedPhototherapyAtomic and Molecular Physics and OpticsElectronic Optical and Magnetic MaterialsTreatment OutcomeErythemaRGB color modelmedicine.symptombusinessHemangiomaBiomedical engineeringJournal of biomedical optics
researchProduct

Evolution of Corneal Graft Survival Over a 30-Year Period and Comparison of Surgical Techniques: A Cohort Study.

2015

Purpose To compare graft survival between 3 10-year periods and according to surgical techniques performed in the last years. Design Cohort study. Methods setting: Regional center (Besancon University Hospital, France). patients: All 1132 patients operated on between 1983 and 2014. Graft and patient baseline characteristics, risk factors for failure, surgical procedures, and postoperative corneal status were collected. main outcome measures: Five-year survival rate in the whole cohort; 1-year and 3-year survival rates, respectively, among 88 patients with endothelial dystrophy (ED) or postoperative bullous keratopathy (PBK) operated on using endothelial lamellar keratoplasty (ELK) or penetr…

AdultGraft RejectionMalemedicine.medical_specialtyKeratoconusTime FactorsCorneal graftVisual AcuityCorneal DiseasesCohort StudiesCorneal Transplantation03 medical and health sciences0302 clinical medicineRisk FactorsMedicineHumansProspective StudiesSurvival rateAgedbusiness.industryHazard ratioGraft SurvivalSurgical proceduresMiddle Agedmedicine.diseaseSurgeryOphthalmologyTreatment OutcomeCohort030221 ophthalmology & optometryBullous keratopathyFemaleFrancebusiness030217 neurology & neurosurgeryCohort studyFollow-Up StudiesAmerican journal of ophthalmology
researchProduct

Mycotoxin Analysis of Human Urine by LC-MS/MS: A Comparative Extraction Study

2017

The lower mycotoxin levels detected in urine make the development of sensitive and accurate analytical methods essential. Three extraction methods, namely salting-out liquid–liquid extraction (SALLE), miniQuEChERS (quick, easy, cheap, effective, rugged, and safe), and dispersive liquid–liquid microextraction (DLLME), were evaluated and compared based on analytical parameters for the quantitative LC-MS/MS measurement of 11 mycotoxins (AFB1, AFB2, AFG1, AFG2, OTA, ZEA, BEA, EN A, EN B, EN A1 and EN B1) in human urine. DLLME was selected as the most appropriate methodology, as it produced better validation results for recovery (79–113%), reproducibility (RSDs < 12%), and repeatability (RSDs…

AdultHealth Toxicology and MutagenesisLiquid-Liquid Extractionlcsh:MedicineUrineToxicology01 natural sciencesArticlechemistry.chemical_compound0404 agricultural biotechnologyTandem Mass SpectrometrymycotoxinsLc ms msHealthy volunteersHumansLC-MS/MSMycotoxinReproducibilityChromatographymycotoxins; urine; optimization; method validation; LC-MS/MSlcsh:R010401 analytical chemistryExtraction (chemistry)method validation04 agricultural and veterinary sciencesRepeatability040401 food scienceurine0104 chemical scienceschemistryExtraction methodsoptimizationChromatography LiquidToxins
researchProduct

Changes in Tear Protein Pattern after Photorefractive Keratectomy

2003

PURPOSE. Changes in tear protein composition of patients who underwent photorefractive keratectomy (PRK) were analyzed. METHODS. Tear samples were obtained from 23 eyes of 23 patients immediately before PRK and on the fourth postoperative day with glass capillaries. Tear proteins were separated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Digital image analysis and evaluation of the densitometric data of the electrophoretic separations were done with BioDoc-Analyze. RESULTS. Analysis of discriminance found a significant difference in the protein patterns (p<0.001). This type of analysis of the electrophoretic densitographs uses all peak information simultaneously. A signifi…

AdultImmunoglobulin APathologymedicine.medical_specialtymedicine.medical_treatmentEye diseaseLacrimal glandPhotorefractive KeratectomyCornea03 medical and health scienceschemistry.chemical_compound0302 clinical medicineCorneaOphthalmologyHumansMedicinePostoperative PeriodEye ProteinsGel electrophoresisbiologybusiness.industryLactoferrinLacrimal ApparatusGeneral MedicineMiddle Agedmedicine.diseaseeye diseasesPhotorefractive keratectomyOphthalmologymedicine.anatomical_structurechemistryTears030221 ophthalmology & optometrybiology.proteinElectrophoresis Polyacrylamide GelLasers Excimersense organsLysozymebusiness030217 neurology & neurosurgeryEuropean Journal of Ophthalmology
researchProduct

Clinicopathological study of oral focal mucinosis : a retrospective case series

2018

Background Oral focal mucinosis (OFM) is a rare soft tissue lesion of unknown etiology that exhibits tumor-like growth. It is considered the oral counterpart of cutaneous focal mucinosis or cutaneous myxoid cyst. This is a retrospective study of oral OFM diagnosed over a period of 42 years at an oral pathology service. Material and Methods Clinical, histopathological and immunohistochemical data were analyzed. Alcian blue staining and S-100 immunohistochemistry were performed. Results Eleven cases were retrieved (4:1 female-to-male ratio). The mean age was 44 years. The gingiva was the most affected site. The main clinical presentation was sessile or pedunculated lesions of fibrous or hyper…

AdultMale0301 basic medicinePathologymedicine.medical_specialtyMucinosesAsymptomatic03 medical and health sciences0302 clinical medicineOral and maxillofacial pathologymedicineHumansGeneral DentistryAgedRetrospective StudiesOral Medicine and Pathologybusiness.industryResearchDiagnosis OralMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseStaining030104 developmental biologyOtorhinolaryngologyCutaneous focal mucinosisUNESCO::CIENCIAS MÉDICAS030221 ophthalmology & optometryEtiologyImmunohistochemistryFemaleSurgerymedicine.symptomDifferential diagnosisMouth DiseasesMyxoid cystbusiness
researchProduct

Corneal confocal scanning laser microscopy in patients with dry eye disease treated with topical cyclosporine

2017

Purpose To investigate the effect of cyclosporine on corneal ultrastructure and on major signs and symptoms of patients with dry eye disease.Patients and methods In this prospective cohort study, patients with dry eye disease were treated with a drop of cyclosporine 0.05% twice daily. Clinical evaluation was carried out at baseline and at months 1, 3, and 6. All patients completed the Ocular Surface Disease Index (OSDI) questionnaire, and tear film break-up time (BUT), fluorescein and lissamine green staining, and Schirmer test were carried out. In vivo confocal microscopy was also performed and epithelial cellular density, keratocyte activation, and subbasal plexus morphology were assessed…

AdultMale0301 basic medicinemedicine.medical_specialtyAdministration TopicalConfocalDry Eye SyndromesGlaucomaCell CountOphthalmic SolutionFollow-Up StudieCorneaImmunosuppressive Agent03 medical and health scienceschemistry.chemical_compound0302 clinical medicineOphthalmologyCorneamedicineOcular Surface Disease IndexFluoresceinProspective cohort studyAgedMicroscopy Confocalbusiness.industryMiddle Agedmedicine.diseaseStainingProspective StudieOphthalmologyTreatment Outcome030104 developmental biologymedicine.anatomical_structureNerve FiberchemistryCyclosporine030221 ophthalmology & optometryFemalebusinessDry Eye SyndromeHumanEye
researchProduct

Predicting presenteeism via effort-reward imbalance and dispositional optimism: Is it the interaction that matters? Results from The Saxony Longitudi…

2019

BACKGROUND The importance of experienced work stress and individual traits as well as their interplay is analyzed with regard to dysfunctional coping behavior in case of sickness. OBJECTIVE The aim of this study was to examine the predictive capability of effort-reward imbalance (ERI) including overcommitment, meaning the intrinsic propensity in terms of excessive work-related expenditure (OC), in consideration of dispositional optimism/pessimism on presenteeism. METHODS A total of 353 men and women aged 38 from the 25th panel wave of The Saxony Longitudinal Study in 2011 were included in the analysis. Effort-reward imbalance (ERI) including overcommitment was assessed with the Effort-Rewar…

AdultMale050103 clinical psychologyLongitudinal studymedia_common.quotation_subjectDispositional optimismDysfunctional familyWorkloadPessimismOccupational StressRewardGermanySurveys and Questionnaires0502 economics and businessHumans0501 psychology and cognitive sciencesLongitudinal StudiesOccupational Healthmedia_commonOptimism05 social sciencesRehabilitationPublic Health Environmental and Occupational HealthRegression analysisPresenteeismExplained variationEffort reward imbalancePessimismPresenteeismFemalePsychology050203 business & managementClinical psychologyWork
researchProduct