Search results for " OS"

Barbed Dental Ti6Al4V Alloy Screw : Design and Bench Testing

2023

Background context. Dental implants are designed to replace a missing tooth. Implant stability is vital to achieving osseointegration and successful implantation. Although there are many implants available on the market, there is room for improvement. Purpose. We describe a new dental implant with improved primary stability features. Study design. Lab bench test studies. Methods. We evaluated the new implant using static and flexion–compression fatigue tests with compression loads, 35 Ncm tightening torque, displacement control, 0.01 mm/s actuator movement speed, and 9–10 Hz load application frequency, obtaining a cyclic load diagram. We applied variable cyclic loadings of prede…

A gloss to the Supreme Court Judgment of 5 March 2019, IV KK 484/17

2019

W glosie przedstawiono problematykę nadzoru prokuratora nad postępowaniem przygotowawczym, prowadzonym przez finansowy organ postępowania przygotowawczego, a także omówiono skutki procesowe objęcia przez prokuratora nadzoru nad takim postępowaniem. Autor wyraża zapatrywanie, iż czynność procesowa prokuratora, wyrażająca się w dalszym przedłużeniu dochodzenia, prowadzonego przez finansowy organ postępowania przygotowawczego, na okres ponad 6 miesięcy, nie jest decyzją o charakterze wpadkowym i nie można jej uznać za czynność techniczną. Czynność ta ma charakter czynności nadzorczej. Konsekwencją przyjęcia, że przedłużenie przez prokuratora, na podstawie art. 153 § 1 zd. 3 k.k.s., na okres po…

Variabilité de la température entre 1951 et 2014 en Allemagne associée à l’évolution de la floraison des pommiers.

2018

Apple tree bloom onset in Germany has advanced by 2 days/decade in 1951-2014 and by 3 days/decade in 1988-2014, behaving similarly in respect to its evolution since 1951 and its sensitivity to temperature to other species’ phenological spring phases. The evolution however was not linear; by conducting a split moving-window dissimilarity analysis (SMWDA) we were able to detect the “break-period” 1987-1989 which coincides with a breakpoint that has been identified in the phases of the North Atlantic Oscillation (NAO). We observed distinct spatial patterns with apple bloom advancing from southwest to northeast and, most interestingly, a longitudinal gradient in the trend of apple bloom onset r…

Earlier appearance of the ossification centre of the femoral head in breast fed versus formula fed infants.

2011

Biosynthesis of scarab beetle pheromones. Enantioselective 8-hydroxylation of fatty acids

1999

Chemical communication in scarab beetles (Coleoptera: Scarabaeidae) is achieved with a wide variety of pheromones, but one typical structure is the γ‐lactone having a long unsaturated hydrocarbon chain. Several species utilize (R,Z)‐5‐(–)‐(oct‐1‐enyl)‐oxacyclopentan‐2‐one (buibuilactone), (R,Z)‐5‐(–)‐(dec‐1‐enyl)‐oxacyclopentan‐2‐one and (S,Z)‐5‐(+)‐(dec‐1‐enyl)‐oxacyclopentan‐2‐one [(R)‐japonilure and (S)‐japonilure]. Using deuterated precursors, we have demonstrated that these compounds are biosynthesized from fatty acids. (9,10‐d4)‐Palmitic acid, (9,10‐d4)‐stearic acid, (9,10‐d2)‐palmitoleic acid, (9,10‐d2)‐oleic acid, (9,10‐d2)‐8‐hydroxypalmitoleic acid and (9,10‐d2)‐8‐hydroxyoleic acid…

Alteraciones osteoarticulares en el músico adulto mayor de instrumentos viento-madera

2021

espanolRESUMEN Objetivo: Valorar si existen cambios a nivel bucodental en adultos mayores, instrumentistas de viento-madera por el uso del instrumento a lo largo de mas de 35 anos de profesion y compararlos con un grupo control. Metodologia: Estudio de tipo observacional, descriptivo de corte transversal, entre musicos profesionales, adultos mayores, de 60 anos o mas, con mas de 35 anos de profesion y que toquen instrumentos de "viento-madera". La muestra inicial de estudio estaba formada por 57 musicos. El instrumento de recogida de datos utilizado se ha elaborado de forma exclusiva. El analisis estadistico se llevo a cabo mediante SPSS Statistics 23.0. Resultados: Media de edad 63 ± 1,28 …

MicroRNA-29b-1 impairs in vitro cell proliferation, self‑renewal and chemoresistance of human osteosarcoma 3AB-OS cancer stem cells

2014

Osteosarcoma (OS) is the most common type of bone cancer, with a peak incidence in the early childhood. Emerging evidence suggests that treatments targeting cancer stem cells (CSCs) within a tumor can halt cancer and improve patient survival. MicroRNAs (miRNAs) have been implicated in the maintenance of the CSC phenotype, thus, identification of CSC-related miRNAs would provide information for a better understanding of CSCs. Downregulation of miRNA-29 family members (miR-29a/b/c; miR‑29s) was observed in human OS, however, little is known about the functions of miR-29s in human OS CSCs. Previously, during the characterization of 3AB-OS cells, a CSC line selected from human OS MG63 cells, we…

Adenocarcinoma dell'endometrio.

2006

Redundancy and synergy in interactions among basic cardiovascular oscillations

2020

The cardiovascular control system comprises a complex network of various control mechanisms operating on many time scales resulting in complex and mutually interconnected output signals (e.g. heart rate, systolic and diastolic blood pressures). The analysis of these interconnections could noninvasively provide an information on the regulatory mechanisms involved in cardiovascular control and thus could be potentially applied to better characterize cardiovascular dysregulation in pathological conditions. Our study demonstrates that the strength of interactions among signals changes with the time scale and as a response to changed autonomic state (orthostasis compared to supine rest). Novel i…

SCD5-induced oleic acid production reduces melanoma malignancy by intracellular retention of SPARC and cathepsin B

2014

A proper balance between saturated and unsaturated fatty acids (FAs) is required for maintaining cell homeostasis. The increased demand of FAs to assemble the plasma membranes of continuously dividing cancer cells might unbalance this ratio and critically affect tumour outgrowth. We unveiled the role of the stearoyl-CoA desaturase SCD5 in converting saturated FAs into mono-unsaturated FAs during melanoma progression. SCD5 is down-regulated in advanced melanoma and its restored expression significantly reduced melanoma malignancy, both in vitro and in vivo, through a mechanism governing the secretion of extracellular matrix proteins, such as secreted protein acidic and rich in cysteine (SPAR…