Search results for " Obese"
showing 10 items of 43 documents
Micro-albuminuria in obese subjects: relationship among body fat distribution, blood pressure and left ventricular structure and function.
1998
OBJECTIVE: To evaluate the relationships among micro-albuminuria, blood pressure and measurements of left ventricular structure and function in centrally and peripherally obese subjects compared with members of a lean control group. METHODS: Centrally obese subjects were subdivided according to whether they had levels of micro-albuminuria higher than 30 mg/24 h (micro-albuminuric group) or lower than or equal to 30 mg/24 h (normo-albuminuric group). For all the subjects we measured heart rate, casual mean blood pressure (MBP), 24 h MBP, total cholesterol level, high-density lipoprotein cholesterol, lipoprotein (a) level, fasting immunoreactive insulin level, plasma renin activity, plasma al…
Noninvasive Flap Preconditioning by Foam-Mediated External Suction Improves the Survival of Fasciocutaneous Axial-Pattern Flaps in a Type 2 Diabetic …
2018
Background Advances in reconstructive surgery are leading to an increased number of flaps at risk for ischemic necrosis, because of either intrinsic (e.g., larger flap size) or extrinsic (e.g., diabetes) factors. Methods to preoperatively improve flap vascularity and limit postoperative ischemia are lacking. Noninvasive suction, using either a macrodeformational silicone cup interface (external volume expansion) or a microdeformational polyurethane foam interface (foam-mediated external volume expansion), has been shown to induce angiogenesis in tissues. The authors investigated whether the preoperative use of external volume expansion/foam-mediated external volume expansion improves flap s…
Obesity and intermittent hypoxia increase tumor growth in a mouse model of sleep apnea.
2012
Background: Intermittent hypoxia and obesity which are two pathological conditions commonly found in patients with obstructive sleep apnea (OSA), potentially enhance cancer progression. Objective: To investigate whether obesity and/or intermittent hypoxia (IH) mimicking OSA affect tumor growth. Methods: A subcutaneous melanoma was induced in 40 mice [22 obese (40–45 g) and 18 lean (20–25 g)] by injecting 106 B16F10 cells in the flank. Nineteen mice (10 obese/9 lean) were subjected to IH (6 h/day for 17 days). A group of 21 mice (12 obese/9 lean) were kept under normoxia. At day 17, tumors were excised, weighed and processed to quantify necrosis and endothelial expression of vascular endothe…
How cognitive behavioural therapy can modulate negative emotional factors as anxiety or depression in obese patients
2015
Estudio de la variación a largo plazo de los parámetros bioquímicos metabólicos en pacientes con obesidad mórbida e intervenidos mediante bypass gást…
2015
INTRODUCCIÓN La Obesidad es ya uno de los mayores problemas de salud pública en los países occidentales y se prevé que en un futuro cercano sea una verdadera epidemia. La naturaleza de este problema no es estética, como es habitual que se valore en nuestro entorno social. Tiene un sinfín de repercusiones. Empezando por las comorbilidades metabólicas que la acompañan, las complicaciones osteoarticulares que desencadena o simplemente el rechazo social que muchas veces genera. Todo ello sumado, da lugar a una pérdida importante de esperanza de vida y de la calidad de la misma. La consecuencia fundamental de la Obesidad y que provoca el mayor riesgo de morbilidad y, sobre todo de mortalidad, es…
Livelli serici di insulina nel soggetto normale (Obeso e non) e nel diabetico obeso Dopo Carico Intragastrico di Aminoacidi
1968
Gli AA. hanno somministrato in 5 soggetti normali normosomici, in 5 obesi metabolicamente sani e in 5 diabetici obesi un carico intragastrico (mediante sondino) di 9 aminoacidi essenziali (arginina, fenil-alanina, valina, leucina, lisina, metionina, isoleucina, istidina, triptofano) per un totale di g 30 ed hanno valutato la risposta insulo-pancreatica. In tutti i casi di soggetti in esame si e messo in evidenza un significativo aumento dell'insulinemia, determinata con metodo radioimmunologico. Il picco insulinemico e stato di 45 ± 11 µU/ml nei normali normosomici, di 65 ± 6 µU/ml negli obesi e di 52 ± 8 nei diabetici obesi, rispettivamente a 75 mp, a 60 mp e a 105 mp. La caduta insulinemi…
Decreased Esophageal Sensitivity to Acid in Morbidly Obese Patients: A Cause for Concern?
2017
Background/Aims: To evaluate esophageal sensitivity to acid between morbidly obese (MO) patients and non-MO controls with abnormal esophageal acid exposure. Methods: We conducted a cross-sectional study of 58 patients: 30 MO (cases) and 28 non-MO (controls). Esophageal symptoms and esophageal sensitivity to 0.1 M hydrochloric acid solution (Bernstein test) were compared between MO and non- MO patients with a prior diagnosis of abnormal esophageal acid exposure. Results: MO patients were less symptomatic than non-MO controls (14% vs 96%; odds ratio [OR], 0.006; 95% confidence interval [CI], 0.001 to 0.075; p=0.000). MO patients were more likely to present with decreased esophageal sensitivit…
Robotic Hysterectomy in Severely Obese Patients With Endometrial Cancer: A Multicenter Study
2015
Abstract Study Objective The aim of this study was to evaluate the surgical and oncologic outcomes of robotic hysterectomy with or without or less pelvic and aortic lymphadenectomy in severely obese patients (body mass index [BMI] ≥ 40 kg/m 2 ) with endometrial cancer. Material and Methods Between August 2010 and November 2014, patients with histologically confirmed endometrial cancer and BMI ≥40 kg/m 2 were deemed eligible for the study and underwent RH with or without pelvic and aortic lymphadenectomy. Results Seventy patients were divided into 3 groups according to their BMI: group A, BMI between 40 and 45 kg/m 2 (50 patients); group B, BMI between 45 and 50 kg/m 2 (10 patients); and gro…
Biliopancreatic Diversion: early complications
1992
The experience and early complications in 66 morbidly obese patients who underwent biliopancreatic diversion are presented. There was one death, due to a pulmonary embolus (PE) at home on the 15th postoperative day. Postoperative complications occurred in nine patients, consisting of gastric hemorrhage (2), gastric outlet obstruction (2), non-lethal PE (1), deep vein thrombosis (1), wound dehiscence (1), and asymptomatic gastric leak (1). In addition, there were 12 superficial wound infections. Four patients required urgent reoperation for gastric hemorrhage (2), gastric outlet obstruction (1), and wound dehiscence (1). The high complication rate is believed to represent the early part of t…