Search results for " Observational"

showing 10 items of 72 documents

Sublimation of icy aggregates in the coma of comet 67P/Churyumov–Gerasimenko detected with the OSIRIS cameras on board Rosetta

2016

Beginning in 2014 March, the OSIRIS (Optical, Spectroscopic, and Infrared Remote Imaging System) cameras began capturing images of the nucleus and coma (gas and dust) of comet 67P/Churyumov¿Gerasimenko using both the wide angle camera (WAC) and the narrow angle camera (NAC). The many observations taken since July of 2014 have been used to study the morphology, location, and temporal variation of the comet's dust jets. We analysed the dust monitoring observations shortly after the southern vernal equinox on 2015 May 30 and 31 with the WAC at the heliocentric distance Rh = 1.53 AU, where it is possible to observe that the jet rotates with the nucleus. We found that the decline of brightness a…

67P/Churyumov-GerasimenkoBrightness010504 meteorology & atmospheric sciences530 PhysicsInfraredCometdata analysis[SDU.ASTR.EP]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Earth and Planetary Astrophysics [astro-ph.EP]Narrow angleComets: individual: 67P/Churyumov-Gerasimenko; Methods: data analysis; Methods: numerical; Methods: observationalFOS: Physical sciencesEquinoxAstrophysics01 natural sciencesAstronomi astrofysik och kosmologiMethods: observationalMethods: data analysisindividual: 67P/Churyumov-Gerasimenko [Comets]0103 physical sciencesAstronomy Astrophysics and Cosmologyobservational [Methods]cometsdata analysis [Methods]010303 astronomy & astrophysics0105 earth and related environmental sciencesobservational method: numerical methodPhysicsEarth and Planetary Astrophysics (astro-ph.EP)Comets: individual: 67P/Churyumov-Gerasimenkomethods: data analysis methods: numerical methods: observational comets: individual: 67P/Churyumov–Gerasimenkonumerical [Methods]biology[SDU.ASTR]Sciences of the Universe [physics]/Astrophysics [astro-ph]Methods: numerical520 AstronomyAstronomyAstronomy and Astrophysics620 Engineeringbiology.organism_classificationOn boardSpace and Planetary Science[SDU]Sciences of the Universe [physics]Sublimation (phase transition)QB651OsirisAstrophysics - Earth and Planetary Astrophysics
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IGR J17503–2636: a candidate supergiant fast X-ray transient

2019

IGR J17503-2636 is a hard X-ray transient discovered by INTEGRAL on 2018 August 11. This was the first ever reported X-ray emission from this source. Following the discovery, follow-up observations were carried out with Swift, Chandra, NICER, and NuSTAR. We report in this paper the analysis and results obtained from all these X-ray data. Based on the fast variability in the X-ray domain, the spectral energy distribution in the 0.5-80 keV energy range, and the reported association with a highly reddened OB supergiant at ~10 kpc, we conclude that IGR J17503-2636 is most likely a relatively faint new member of the supergiant fast X-ray transients. Spectral analysis of the NuSTAR data revealed …

AccretionX-ray transientAstrophysics::High Energy Astrophysical PhenomenaCyclotronFOS: Physical sciencesAstrophysics01 natural scienceslaw.inventionbinaries [x-rays]X-rays: binariesSettore FIS/05 - Astronomia E AstrofisicaMethods: observationalBinaries: closelaw0103 physical sciencesSpectral analysis010303 astronomy & astrophysicsPhysicsHigh Energy Astrophysical Phenomena (astro-ph.HE)individuals: IGR J17503-2636 [X-rays]010308 nuclear & particles physicsScatteringAstronomy and AstrophysicsStars: neutronAccretion (astrophysics)Neutron starAccretion diskSpace and Planetary ScienceSpectral energy distributionSupergiantAstrophysics - High Energy Astrophysical PhenomenaAstronomy & Astrophysics
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Relation between diagnosis of atheromatous plaque from orthopantomographs and cardiovascular risk factors. A study of cases and control subjects.

2014

Background In recent years the use of orthopantomography has been proposed as a low-cost, reliable and non-invasive diagnostic medium for detecting atheromatous plaque. The purpose of this study was to correlate the presence of carotid calcifications (atheroma) in orthopantomographs with specific risk factors for cerebrovascular accidents (previous cerebrovascular accidents, arterial hypertension, and diabetes). Material and Methods The methods used in this observational study of cases and control subjects followed STROBE (Strengthening the Reporting of Observational studies in Epidemiology) recommendations. The study analyzed a total of 1,602 panoramic radiographs taken for dental diagnost…

AdultCarotid Artery DiseasesMalemedicine.medical_specialtyAdolescentOdontologíaStrengthening the reporting of observational studies in epidemiology03 medical and health sciencesYoung Adult0302 clinical medicineRisk FactorsDiabetes mellitusRadiography PanoramicmedicineHumans030212 general & internal medicinecardiovascular diseasesYoung adultVascular CalcificationGeneral DentistryAgedAged 80 and overbusiness.industryResearchIncidence (epidemiology)Case-control study030206 dentistryMiddle AgedMedically compromised patients in Dentistrymedicine.disease:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludPlaque AtheroscleroticAtheromaOtorhinolaryngologySample size determinationCardiovascular DiseasesCase-Control StudiesUNESCO::CIENCIAS MÉDICASSurgeryObservational studyFemaleRadiologybusiness
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Addressing the impact of SARS-CoV-2 infection in persons with congenital bleeding disorders: The Italian MECCOVID-19 study

2021

congenital bleeding disorders

AdultInheritedMalePediatricsmedicine.medical_specialty2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)congenital bleeding disorderscongenital bleeding disorderSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)haemophiliaHemorrhageHaemophiliaLetter to the EditorsSARS‐CoV‐2Young AdultBlood Coagulation Disorders InheritedCOVID‐19congenital bleeding disorders; COVID-19; epidemiology; haemophilia; observational study; SARS-CoV-2; Adult; Aged; Blood Coagulation Disorders Inherited; COVID-19; Child Preschool; Disease Management; Female; Hemorrhage; Humans; Italy; Male; Middle Aged; SARS-CoV-2; Young AdultEpidemiologymedicineHumansYoung adultDisease management (health)ChildPreschoolLetter to the EditorGenetics (clinical)Agedbusiness.industrySARS-CoV-2COVID-19Disease ManagementHematologyGeneral MedicineBlood Coagulation DisordersMiddle Agedmedicine.diseaseItalySARS-CoV-2.Child PreschoolObservational studyepidemiologyobservational studyFemalebusiness
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Association between antithrombotic treatment and outcomes at 1-year follow-up in patients with atrial fibrillation: the EORP-AF General Long-Term Reg…

2019

Aims In recent years, stroke prevention in patients with atrial fibrillation (AF) has radically changed, with increasing use of non-vitamin K antagonist oral anticoagulants (NOACs). Contemporary European data on AF thromboprophylaxis are needed. Methods and results We report 1-year follow-up data from the EURObservational Research Programme in Atrial Fibrillation (EORP-AF) General Long-Term Registry. Outcomes were assessed according to antithrombotic therapy. At 1-year follow-up, 9663 (88.0%) patients had available data for analysis: 586 (6.1%) were not treated with any antithrombotic; 681 (7.0%) with antiplatelets only; 4066 (42.1%) with vitamin K antagonist (VKA) only; 3167 (32.8%) with …

AdultMaleAcute coronary syndromemedicine.medical_specialtymedicine.drug_classHemorrhageOutcomes030204 cardiovascular system & hematologyLower riskRisk Assessment[SHS]Humanities and Social Sciences03 medical and health sciences0302 clinical medicineFibrinolytic AgentsRisk FactorsPhysiology (medical)Internal medicineCause of DeathAntithromboticMedicineHumans030212 general & internal medicineProspective StudiesRegistriesPractice Patterns Physicians'StrokeAgedEORP-AF registryAged 80 and overAntithrombotic therapybusiness.industryProportional hazards modelAtrial fibrillationVitamin K antagonistMiddle Agedmedicine.diseaseAtrial fibrillationObservational registriesEuropeStrokeFemaleCardiology and Cardiovascular MedicinebusinessAntithrombotic therapy; Atrial fibrillation; EORP-AF registry; Observational registries; Outcomes; StrokeFibrinolytic agentFollow-Up Studies
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The what and how of observational learning

2007

Abstract Neuroimaging evidence increasingly supports the hypothesis that the same neural structures subserve the execution, imagination, and observation of actions. We used repetitive transcranial magnetic stimulation (rTMS) to investigate the specific roles of cerebellum and dorsolateral prefrontal cortex (DLPFC) in observational learning of a visuomotor task. Subjects observed an actor detecting a hidden sequence in a matrix and then performed the task detecting either the previously observed sequence or a new one. rTMS applied over the cerebellum before the observational training interfered with performance of the new sequence, whereas rTMS applied over the DLPFC interfered with performa…

AdultMaleCognitive Neurosciencemedicine.medical_treatmentrTMS cerebellum DLPFCPrefrontal CortexExperimental and Cognitive PsychologyCognitive neurosciencecerebellum; frontal cortex; observational learning; tmsbehavioral disciplines and activitiesTask (project management)NOBehavioral NeuroscienceMental ProcessesNeuroimagingtmsReference ValuesCerebellummental disordersmedicineBiological neural networkHumansObservational learningReference Values; Analysis of Variance; Humans; Cerebellum; Neural Inhibition; Prefrontal Cortex; Motor Skills; Imitative Behavior; Problem Solving; Social Perception; Imagination; Mental Processes; Adult; Transcranial Magnetic Stimulation; Female; MaleProblem SolvingAnalysis of VarianceSettore M-PSI/02 - Psicobiologia E Psicologia Fisiologicafrontal cortexNeural InhibitionCognitionImitative BehaviorTranscranial Magnetic StimulationDorsolateral prefrontal cortexTranscranial magnetic stimulationobservational learningmedicine.anatomical_structureSocial Perceptionnervous systemMotor SkillsImaginationSettore MED/26 - NeurologiaFemalePsychologyNeurosciencepsychological phenomena and processesCognitive psychology
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Real-world evidence from a European cohort study of patients with treatment resistant depression : Baseline patient characteristics

2021

Journal of affective disorders 283, 115-122 (2021). doi:10.1016/j.jad.2020.11.124

AdultMaleDisease burden; Health-related quality of life; Major depressive disorder; Observational study; Patient-reported outcomes; Socio-economic status; Adult; Cohort Studies; Europe; Female; Humans; Male; Middle Aged; Quality of Life; Depressive Disorder Major; Depressive Disorder Treatment-Resistantmedicine.medical_specialtyHealth-related quality of lifeSocio-economic statusMajor depressive disorderCohort Studies03 medical and health sciencesDepressive Disorder Treatment-Resistant0302 clinical medicineQuality of lifeObservational studyInternal medicinemedicineHumansMedical historyDepression (differential diagnoses)Disease burdenDepressive DisorderDepressive Disorder MajorPatient-reported outcomesDisease burden Health-related quality of life Major depressive disorder Observational study Patient-reported outcomes Socio-economic statusbusiness.industryTreatment-ResistantMajorDisease burdenMiddle Agedmedicine.disease030227 psychiatry3. Good healthEuropePsychiatry and Mental healthClinical PsychologyPresenteeismQuality of LifeMajor depressive disorderFemalebusinessTreatment-resistant depression030217 neurology & neurosurgeryCohort study
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Transitional hemodynamics in infants of diabetic mothers by targeted neonatal echocardiography, electrocardiography and peripheral flow study

2017

Objective: Metabolic alterations of intrauterine environment in diabetes mellitus (DM) lead to fetal cardiac dysfunctions that can persist after birth. The aim of the study was to assess the cardiovascular adaptation in infants born to diabetic mothers (IDM) with different degrees of glycometabolic control, in relation to revised guidelines for diagnosis of DM and quality improvements in neonatal care. Materials and methods: An observational case-control study was conducted on IDM with gestational, type 1 and type 2 DM. Relevant maternal and neonatal anamnestic, clinical and laboratory data were analyzed. Electrocardiographic and echocardiographic analyses, including structural and systo-…

AdultMaleDoppler-echocardiographyPediatricsmedicine.medical_specialtycerebrovascular circulation; Doppler-echocardiography; glucose metabolism disorders; heart function; Observational case-control study; Pediatrics Perinatology and Child Health; Obstetrics and GynecologyHemodynamics030204 cardiovascular system & hematologyDoppler echocardiographyElectrocardiography03 medical and health sciencesheart function0302 clinical medicineObstetrics and gynaecologyPregnancyglucose metabolism disorderDiabetes mellitusmedicineHumansObservational case-control studyFetus030219 obstetrics & reproductive medicinemedicine.diagnostic_testbusiness.industryfungiInfant Newbornfood and beveragesObstetrics and GynecologyHeartmedicine.diseaseCerebrovascular CirculationPeripheralDiabetes GestationalEchocardiographyCase-Control StudiesPediatrics Perinatology and Child Healthcardiovascular systemFemalecerebrovascular circulationbusinessElectrocardiographyBlood Flow Velocity
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The Italian Multiple Sclerosis Database Network (MSDN): The risk of worsening according to IFNβ exposure in multiple sclerosis

2006

We evaluated the risk of worsening according to the length of exposure to interferon beta (IFNβ)ina large cohort of 2090 multiple sclerosis patients collected by the Italian MS Database Network. Overall 44-140 patient-visits with a follow-up of 22-143 patient-years were evaluated. Forty-one per cent of patients were exposed to IFNβ for up to 2 years, 39% for 2- 4 years and 20% for more than 4 years. A Cox regression model was used to analyse two clinical outcomes: disability progression and worsening of relapse rate. The technique of propensity score was applied to reduce bias in the comparison of non-randomized groups. The risks of disability progression (HR=0.23; 95% CI: 0.17 - 0.30) and …

AdultMaleTime Factorscomputer.software_genreCentral nervous system diseaseCohort Studies03 medical and health sciencesDisability Evaluation0302 clinical medicineAdjuvants ImmunologicmedicineHumansImmunologic Factors030212 general & internal medicineRisk factorMULTIPLE SCLEROSISDemographyProportional Hazards ModelsRISKAnalysis of VarianceDatabasebusiness.industryProportional hazards modelMultiple sclerosisInterferon-betaIFNP; Long term effectiveness; Multiple sclerosis; Observational studies;Middle Agedmedicine.diseaseTreatment OutcomeNeurologyDatabases as TopicItalyPropensity score matchingDisease ProgressionRegression AnalysisObservational studyFemaleNeurology (clinical)Analysis of variancebusinesscomputer030217 neurology & neurosurgeryCohort study
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Post-marketing of disease modifying drugs in multiple sclerosis: an exploratory analysis of gender effect in interferon beta treatment.

2009

Background: There are a few and conflicting results from randomised controlled trials (RCTs) pertaining to the influence of gender in response to currently used disease modifying drugs in Multiple Sclerosis (MS). Observational studies may be especially valuable for answering effectiveness questions in subgroups not studied in RCTs. Objective: To conduct a post-marketing analysis aimed to evaluate the gender effect on Interferon beta (IFN beta) treatment response in a cohort of relapsing (RR) MS patients. Methods: A cohort of 2570 IFN beta-treated RRMS was prospectively followed for Lip to 7 years in 15 Italian MS Centers. Cox proportional hazards regression models were used to assess gender…

AdultMalemedicine.medical_specialtyMultiple SclerosisPropensity scoreDiseasegender; interferon beta; multiple sclerosis; observational study; propensity scoreLower riskSeverity of Illness IndexMultiple sclerosis Interferon beta Gender Observational study Propensity scoreCohort StudiesDisability EvaluationYoung AdultSex Factorsgender multiple sclerosis treatment interferonDouble-Blind MethodInternal medicineObservational studymedicinegenderConfidence IntervalsOdds RatioProduct Surveillance PostmarketingHumansImmunologic FactorsMultiple sclerosiProportional Hazards ModelsExpanded Disability Status ScaleProportional hazards modelbusiness.industryMultiple sclerosisDrug Administration RoutesInterferon-betamedicine.diseaseInterferon betaSurgeryNeurologyItalyCohortPropensity score matchingRegression AnalysisSettore MED/26 - NeurologiaObservational studyFemaleNeurology (clinical)business
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