Search results for " Obstructive."
showing 10 items of 477 documents
Cluster Analysis of Home Polygraphic Recordings in Symptomatic Habitually-Snoring Children: A Precision Medicine Perspective
2022
(1) Background: Sleep-disordered breathing (SDB) is a frequent problem in children. Cluster analyses offer the possibility of identifying homogeneous groups within a large clinical database. The application of cluster analysis to anthropometric and polysomnographic measures in snoring children would enable the detection of distinctive clinically-relevant phenotypes; (2) Methods: We retrospectively collected the results of nocturnal home-based cardiorespiratory polygraphic recordings and anthropometric measurements in 326 habitually-snoring otherwise healthy children. K-medoids clustering was applied to standardized respiratory and anthropometric measures, followed by Silhouette-based statis…
Biomarkers in obstructive respiratory diseases: An update
2012
Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation of the airways, with the involvement of many inflammatory cells and mediators. Traditionally, this inflammation is thought to spread to a systemic level, thus inducing damage of different organs. However, other pathogenetic mechanisms could take part to the above-described process, and some open questions need to be solved. Due to the burden and increasing prevalence of COPD, the opportunity to find biomarkers that can potentially be useful in identifying individuals with the disease, or better, prior to symptoms onset, to diagnose and properly manage the respiratory symptoms, as well as to evaluate the re…
Burden of Comorbidities in Patients with OSAS and COPD-OSAS Overlap Syndrome
2021
Background and Objectives: Obstructive sleep apnea syndrome (OSAS) and chronic obstructive pulmonary disease (COPD) are usually associated with multi-morbidity. The aim of this study was to retrospectively investigate the prevalence of comorbidities in a cohort of patients with OSAS and COPD-OSAS overlap syndrome (OS) patients and to explore differences between these two groups. Materials and Methods: Included were consecutive OS patients and OSAS patients who had been referred to our sleep laboratory, and were matched in terms of sex, age, BMI, and smoking history. Presence of comorbidities was recorded based on their medical history and after clinical and laboratory examination. Results: …
Coexistence of frailty syndrome and the level of health behaviors in elderly patients with chronic obstructive pulmonary disease
2023
Wprowadzenie: Przyspieszenie tempa starzenia się populacji, związane z tym ryzyko występowania zespołu słabości oraz wzrost liczby osób żyjących z przewlekłą obturacyjną chorobą płuc (POChP) powodują, że przyszłe kierunki polityki zdrowotnej powinny się skupiać na działaniach z zakresu promocji zdrowia, potęgowaniu zachowań prozdrowotnych, utrzymaniu lub poprawie sprawności funkcjonalnej starzejących się ludzi. Cel pracy: Analiza współwystępowania zespołu kruchości oraz nasilenia zachowań zdrowotnych u pacjentów w wieku podeszłym z POChP, jak również ustalenie czynników determinujących nasilenie zachowań zdrowotnych. Materiał i metody: Zbadano 100 pacjentów z rozpoznaniem POChP (średnia wie…
Comorbidities and clinical outcomes of a lung cancer screening trial participants with chronic obstructive pulmonary disease in three-year follow-up
2022
To improve the effectiveness of lung cancer screening using low-dose computed tomography (LDCT), the presence of smoking-related comorbidities that may significantly affect mortality in this group should be taken into account. Material and methods: A questionnaire survey and spirometry tests were conducted in a group of 730 respondents as part of a lung cancer screening study between 2016 and 2018. People diagnosed with COPD underwent a three-year follow-up to assess the incidence of medical events. Results: Our study confirmed that cardiovascular diseases (CVDs) were the most common comorbidities in patients who were diagnosed with COPD and participated in LDCT lung cancer screening. Among…
Noninvasive Ventilation in Critically Ill Patients
2015
Since its first application in the late 1980s, noninvasive ventilation (NIV) has been the first-line intervention for certain forms of acute respiratory failure. NIV may be delivered through the patient's mouth, nose, or both using noninvasive intermittent positive pressure ventilation or continuous positive airway pressure. When applied appropriately, NIV may reduce morbidity and mortality and may avert iatrogenic complications and infections associated with invasive mechanical ventilation. This article provides physicians and respiratory therapists with a comprehensive, practical guideline for using NIV in critical care. © 2015 Elsevier Inc.
Expertise préalable à la création d’un tableau de maladie professionnelle ou à l’élaboration de recommandations aux comités régionaux dereconnaissanc…
2022
Le plan d’actions sur les produits phytopharmaceutiques publié en avril 2018 vise notamment, sur la base des recommandations formulées par l’Inspection générale des affaires sociales, l’Inspection générale des finances et le Conseil général de l’alimentation, de l’agriculture etdes espaces ruraux dans leur rapport conjoint de janvier 2018, à améliorer la prise en charge des maladies professionnelles liées aux pesticides.Dans ce cadre, les pouvoirs publics ont, par courrier en date du 24 avril 2018, saisi l’Institut national de la santé et de la recherche médicale (Inserm) afin d’actualiser l’expertise collective « Pesticides : effets sur la santé » parue en 2013. Cette expertise synthétise …
Why, whether and how to use high-flow nasal therapy in acute exacerbations of chronic obstructive pulmonary disease
2021
Noninvasive ventilation (NIV) represents the standard of care for respiratory support of patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) developing acute hypercapnic respiratory failure (AHRF) [1]. NIV has been shown to reduce patient’s work of breathing and mortality and be feasibly implemented in various hospital location facilities at different timing, based on the severity of AHRF [2] and it is also widely used in clinical practice by physicians [3]. However, clinicians’ knowledge, experience and expertise in the management of NIV are crucial for its success in order to overcome common problems that may lower its effectiveness such as patients’ discomf…
High flow nasal therapy in Acute Exacerbation of COPD: Ready for the prime time?
2021
Focus on functional delayed central sleep apnea following cervical laminectomy. An example of respiratory dysfunction in restorative neurosurgical pr…
2017
In sleep-related breathing disorders, sleep apnea is a clinical symptom that can be categorized as obstructive sleep apnea (OSA) or mixed apnea by analysis using poly-somnography. The occurrence of delayed central sleep apnea (CSA) is an extremely rare complication of cervical laminectomy for spondylotic myelopathy. So far only three studies concerning such an event have been reported in the literature. Naim-ur-Rahman, in 1994, reported a case of postoperative CSA following C3-C6 laminectomy, and Visocchi and colleagues, in 2014, in two studies, stressed the lack of association with any other neurological sign of spinal cord damage. No definitive mechanism has been recognized so far for del…