Search results for " Obstructive."

showing 10 items of 477 documents

Schwannoma of the common bile duct: a rare cause of obstructive jaundice.

2003

The endoscopic diagnosis of bile duct lesions has improved over recent years through the introduction of cholangioscopy and intraductal ultrasound. Combining this with biopsies examined using routinely administered immunohistochemical markers, the diagnosis of tumors of the extrahepatic bile duct can be improved substantially. We report a rare case of a schwannoma of the bile duct causing obstructive jaundice.

AdultMalemedicine.medical_specialtyCommon Bile Duct NeoplasmsSchwannomadigestive systemGastroenterologyInternal medicinemedicineHumansCholangiopancreatography Endoscopic RetrogradeCommon bile ductmedicine.diagnostic_testbusiness.industryBile ductGastroenterologyAnatomical pathologyJaundicemedicine.diseaseEndoscopyJaundice Obstructivemedicine.anatomical_structureHistopathologymedicine.symptombusinessComplicationNeurilemmomaEndoscopy
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Smoking in COPD Patients: A New Clinical Phenotype?

2017

AdultMalemedicine.medical_specialtyCopd patientsmedicine.medical_treatmentMEDLINEPulmonary diseaseSymptom assessmentPulmonary Disease Chronic Obstructive03 medical and health sciences0302 clinical medicineForced Expiratory VolumeInternal medicinePrevalencemedicineHumans030212 general & internal medicineClinical phenotypeAgedAged 80 and overbusiness.industrySmokingGeneral MedicineMiddle AgedPhenotypePhenotype030228 respiratory systemSpainSmoking cessationFemaleSmoking CessationSymptom AssessmentbusinessArchivos de Bronconeumología (English Edition)
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Investigation into isoprenaline resistance in patients with obstructive lung disease

1974

12 patients with chronic obstructive lung disease have been studied in an investigation regarding the causes of resistance to isoprenaline. The effects of repeated intravenous doses of 10 µg isoprenaline were assessed by cross over comparison before and after infusions of isoprenaline and a placebo; the infusions lasted for 35 to 40 min and the amount of isoprenaline infused was 0.5 µg/min. Total resistance, thoracic gas volume (whole-body plethysmography) and heart rate (ECG) were measured. No decrease in bronchospasmolytic or positive chronotopic effects on single isoprenaline injections could be demonstrated after prolonged infusions of isoprenaline.

AdultMalemedicine.medical_specialtyDrug ResistanceDrug resistancePlaceboPlacebosElectrocardiographyHeart RateIsoprenalineInternal medicineHeart ratemedicineHumansPlethysmographInfusions ParenteralPharmacology (medical)Lung Diseases ObstructiveAgedPlethysmography Whole BodyAsthmaPharmacologyAnalysis of VarianceClinical Trials as Topicbusiness.industryAirway ResistanceIsoproterenolGeneral MedicineMiddle Agedmedicine.diseaseStimulation ChemicalObstructive lung diseaseAirway ObstructionBronchodilatationAnesthesiaInjections IntravenousCardiologyFemalebusinessmedicine.drugEuropean Journal of Clinical Pharmacology
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Insomnia symptoms combined with nocturnal hypoxia associate with cardiovascular comorbidity in the European sleep apnea cohort (ESADA)

2018

WOS: 000482433800011

AdultMalemedicine.medical_specialtyInsomniaNeurologyComorbiditySettore MED/10 - Malattie Dell'Apparato RespiratorioNocturnalHypoxemiaHypoxemia03 medical and health sciences0302 clinical medicineRisk FactorsSleep Initiation and Maintenance DisordersInternal medicinemental disordersPrevalenceInsomniaHumansMedicineHypoxiaSleep Apnea Obstructivebusiness.industrySleep Breathing Physiology and Disorders • Original ArticleSleep apneaSleep apneaMiddle AgedCardiovascular disease ; Comorbidity ; Hypoxemia ; Insomnia ; Phenotype ; Sleep apnea.Hypoxia (medical)Cardiovascular diseasemedicine.diseaseComorbidityCircadian Rhythmnervous system diseasesEuropePhenotype030228 respiratory systemOtorhinolaryngologyCardiovascular DiseasesCohortFemaleHuman medicineNeurology (clinical)medicine.symptombusiness030217 neurology & neurosurgerySleep and Breathing
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Parathyroid Hormone as a Novel Biomarker for Chronic Obstructive Pulmonary Disease: Korean National Health and Nutrition Examination Survey

2015

Objective To understand and predict chronic obstructive pulmonary disease (COPD), a biomarker that reflects disease severity is needed. Research Design and Methods Data from 10269 adults aged over 40 years of age were retrieved from the Korea National Health and Nutrition Examination Survey (KNHANES), and 1302 patients met the criteria for COPD. The association between values of vitamin D and parathyroid hormone (PTH), and COPD severity including lung function and quality of life, were analyzed. Results In COPD patients, lung function was inversely related to PTH values (P = 0.02 for FVC [% predicted]; P < 0.001 for FEV1 [% predicted]); however, the association of lung function with vitamin…

AdultMalemedicine.medical_specialtyNational Health and Nutrition Examination Surveylcsh:MedicineParathyroid hormonePulmonary function testingPulmonary Disease Chronic ObstructiveFEV1/FVC ratioInternal medicineRepublic of KoreaVitamin D and neurologyHumansMedicineVitamin Dlcsh:ScienceLungAgedCOPDMultidisciplinarybusiness.industrylcsh:RMiddle AgedNutrition Surveysmedicine.diseaseRespiratory Function Testsrespiratory tract diseasesEndocrinologyParathyroid HormoneMultivariate AnalysisQuality of LifeBiomarker (medicine)lcsh:QFemalebusinessBody mass indexBiomarkersResearch ArticlePLOS ONE
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Vitamin D deficiency in patients evaluated for obstructive sleep apnea: is it associated with disease severity?

2019

Purpose: The aim of the present study was to assess vitamin D levels in a large cohort of OSA patients and to investigate possible correlations with clinical and polysomnographic parameters. Methods: In this cross-sectional study, 685 consecutive patients underwent type 1 polysomnography (PSG) for OSA diagnosis. They were grouped according to apnea–hypopnea index (AHI) as mild, moderate, and severe. Patients with AHI &lt; 5 served as controls. Demographic, PSG data, and serum levels of vitamin D were measured and compared between groups. Results: OSA was diagnosed in 617 of the patients (90%). Of those, 94 (15%) had mild OSA, 150 (24%) moderate OSA, and 373 (61%) severe OSA. The risk of vit…

AdultMalemedicine.medical_specialtyNeurologyVitamin D deficiency.PolysomnographyPolysomnographySettore MED/10 - Malattie Dell'Apparato RespiratorioGastroenterologyvitamin D deficiencyCohort Studies03 medical and health sciences0302 clinical medicinestomatognathic systemInternal medicinemedicineVitamin D and neurologyHumansVitamin DSleep Apnea Obstructivemedicine.diagnostic_testbusiness.industryPatient AcuityMiddle Agedmedicine.diseaseVitamin D DeficiencyObesityObstructive sleep apneanervous system diseasesrespiratory tract diseasesObstructive sleep apneaCross-Sectional Studies030228 respiratory systemOtorhinolaryngologyOtorhinolaryngologyCohortFemaleNeurology (clinical)business030217 neurology & neurosurgerySleepbreathing = SchlafAtmung
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Multilevel temperature-controlled radiofrequency therapy of soft palate, base of tongue, and tonsils in adults with obstructive sleep apnea.

2003

Objectives/hypothesis The concept of two-level pharyngeal collapse in patients with obstructive sleep apnea is too simplified. Aggressive multilevel surgeries addressing several airway segments, including skeletal surgery, demonstrate improved success rates. Study design The study aimed to evaluate the safety and efficacy of multilevel radiofrequency application to soft palate, tonsils, and base of tongue in 16 white patients (mean age, 56.9 +/- 11.1 y; mean body mass index, 27.3 +/- 2.6 kg/m2) with obstructive sleep apnea. There was one dropout. Therapeutic effects after one treatment session were assessed 20.6 +/- 12.6 weeks postoperatively. Treatment outcome measurements were based on Ep…

AdultMalemedicine.medical_specialtyPolysomnographyPalatine TonsilPolysomnographyTongueTongueRespiratory disturbance indexmedicineHumansAgedSleep Apnea Obstructivemedicine.diagnostic_testSoft palatebusiness.industryEpworth Sleepiness ScaleSleep apneaMiddle Agedmedicine.diseaseSurgeryOtorhinolaryngologic Surgical ProceduresObstructive sleep apneamedicine.anatomical_structureTreatment OutcomeOtorhinolaryngologyAnesthesiaCatheter AblationFemalePalate SoftAirwaybusinessThe Laryngoscope
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The Apnea-Hypopnea Index Underestimates Systemic Inflammation in Women with Sleep-Disordered Breathing.

2018

Evidence suggests that sleep-related respiratory and related metabolic compromise may vary between females and males with sleep-disordered breathing (SDB). Our purpose was to elucidate possible gender differences in sleep-associated respiratory and inflammatory parameters in patients with SDB.A consecutive number of SDB patients (46 females and 167 males) who underwent polysomnography were retrospectively reviewed. Fibrinogen and C-reactive protein (CRP) concentration, apnea index (ApnI), hypopnea index (HypI), apnea-hypopnea index (AHI), average and minimal SpOApnI and AHI were significantly higher in males. Correlation analysis revealed striking gender differences: only in females, CRP co…

AdultMalemedicine.medical_specialtyPolysomnographyPolysomnography030204 cardiovascular system & hematologyBody Mass Index03 medical and health sciences0302 clinical medicineSleep Apnea SyndromesRisk FactorsInternal medicinemedicineHumansObesityAgedRetrospective StudiesInflammationSleep Apnea Obstructivebiologymedicine.diagnostic_testbusiness.industryC-reactive proteinSnoringApneaFibrinogenGeneral MedicineMiddle Agedmedicine.diseasenervous system diseasesrespiratory tract diseasesObstructive sleep apneaC-Reactive Protein030228 respiratory systemApnea–hypopnea indexCardiologyBreathingbiology.proteinFemalemedicine.symptombusinessHypopneaBody mass indexJournal of women's health (2002)
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Impact of Baseline and Induced Dyspnea on the Quality of Life of Patients With COPD

2008

Objective Dyspnea is the main symptom of chronic obstructive pulmonary disease (COPD) and as such is an important determinant of health-related quality of life. It is, however, weakly correlated to severity of obstruction and there is little information available on how it exercises its effect on health-related quality of life. The aims of this study were to identify the determinants of baseline dyspnea and to ascertain how that factor influences the health-related quality of life of patients with COPD. Patients and methods A total of 101 patients with COPD were studied. Tests included full lung function assessment, the bronchial provocation test (n=70), and the 6-minute walk test. The foll…

AdultMalemedicine.medical_specialtyPulmonary Disease Chronic ObstructiveQuality of lifeInternal medicinemedicineHumansIn patientProspective StudiesBaseline (configuration management)Depression (differential diagnoses)AgedAged 80 and overCOPDbusiness.industryGeneral MedicineMiddle AgedExplained variationmedicine.diseaserespiratory tract diseasesDyspneaBronchial provocationQuality of LifePhysical therapyAnxietyFemalemedicine.symptombusinessArchivos de Bronconeumología ((English Edition))
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Oral appliance therapy in obstructive sleep apnea: Long-term adherence and patients experiences.

2018

Background Despite the advances in the treatment of obstructive sleep apnea (OSA) with mandibular advancement appliances (MAA), their effectiveness is dependent on the patients’ compliance. Our aims were to evaluate the long-term adherence to MAA therapy and patients’ experiences of the treatment in OSA. Material and Methods Sixty-nine patients (52 males, 17 females; Mean age: 54.4±10.8 years) were included in the study. The subjects were mild (56%) and moderate (44%) OSA patients who had been treated using MAA at least 4 years prior to the study. A phone survey was used to determine the demographic characteristics of the patients, as well as to assess self-reported adherence to therapy, su…

AdultMalemedicine.medical_specialtyTime FactorsOral applianceDisease03 medical and health sciences0302 clinical medicinePatient satisfactionInternal medicinemedicineHumansGeneral DentistryIncome.statusAgedSleep Apnea Obstructivebusiness.industryResearchSleep apneaMiddle Agedmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Medically compromised patients in DentistryTemporomandibular jointObstructive sleep apneamedicine.anatomical_structure030228 respiratory systemOtorhinolaryngologyPatient SatisfactionUNESCO::CIENCIAS MÉDICASMarital statusPatient ComplianceSurgeryFemalebusinessMandibular Advancement030217 neurology & neurosurgeryMedicina oral, patologia oral y cirugia bucal
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