Search results for " Opera"
showing 10 items of 3606 documents
An efficient algorithm for stopping on a sink in a directed graph
2013
Abstract Vertices of an unknown directed graph of order n are revealed one by one in some random permutation. At each point, we know the subgraph induced by the revealed vertices. Our goal is to stop on a sink, a vertex with no out-neighbors. We show that if a sink exists this can be achieved with probability Θ ( 1 / n ) , which is best possible.
Confidence-based Somatic Mutation Evaluation and Prioritization
2012
Next generation sequencing (NGS) has enabled high throughput discovery of somatic mutations. Detection depends on experimental design, lab platforms, parameters and analysis algorithms. However, NGS-based somatic mutation detection is prone to erroneous calls, with reported validation rates near 54% and congruence between algorithms less than 50%. Here, we developed an algorithm to assign a single statistic, a false discovery rate (FDR), to each somatic mutation identified by NGS. This FDR confidence value accurately discriminates true mutations from erroneous calls. Using sequencing data generated from triplicate exome profiling of C57BL/6 mice and B16-F10 melanoma cells, we used the exist…
Family business internationalization: an insight into opportunities and challenges.
2020
The theme of internationalization in family businesses is a highly topical issue that is increasingly attracting management scholars. This is because, in addition of being a particular type of business (Alcorn, 1982), they play a central role in most economies worldwide. Accounting for 65-80 percent of all the world’s firms, they generate around 70-90 percent of annual global GDP, and are the source of 50-80 percent of new jobs in most countries. Their essence lies in the close bond they have with their founders and above all, in the family’s involvement in the business ownership and management (Franco and Prata, 2019). This bond may prove to be a limit for fuelling internationalization pro…
Success factors of Polish family businesses
2017
This article presents the results of a study carried out among family businesses operating in Poland. It is intended to supplement previously generated knowledge in the area of the operation of family businesses in the specific socio-economic and legal conditions in Poland. The objective was to collate the opinions of entrepreneurs regarding the need for visibility of the family and the family business status in business relations and the marketing activities of enterprises. The data were collected using in-depth interviews with the Polish family business owners. This paper outlines the conclusion of the study with respect to success factors such as: the trust among the family members, flex…
Choice between alternative investments in agriculture: The role of organic farming to avoid the abandonment of rural areas
2015
Abstract Sicily has a long tradition in citrus fruit cultivation that, with vineyard and olive tree, represents the main Mediterranean tree crops. Since many Sicilian farmers in recent years have decided to abandon conventional lemon orchards, in this paper we have evaluated the financial sustainability of organic lemon production by comparing it with the conventional one. Financial analysis has been carried out in a case study on the northwestern coast of Sicily, considering a 50-year economic life of an orchard. The results, per hectare of area, showed a clear advantage of organic lemon orchard. This was due to fewer labor requirements and to greater market appreciation for organic produc…
A Survey on Proxy Mobile IPv6 Handover
2016
[EN] As wireless technologies have been improving in recent years, a mobility management mechanism is required to provide seamless and ubiquitous mobility for end users who are roaming among points of attachment in wireless networks. Thus, Mobile IPv6 was developed by the Internet Engineering Task Force (IETF) to support the mobility service. However, Mobile IPv6 is unable to fulfill the requirements of real-time applications, such as video streaming service and voice over IP service, due to its high handover (HO) latency. To address this problem, Proxy Mobile IPv6 (PMIPv6) has been introduced by the IETF. In PMIPv6, which is a network-based approach, the serving network controls mobility m…
Safety studies of a hydrogen refuelling station: Determination of the occurrence frequency of the accidental scenarios
2009
At present, the hydrogen vehicles technology appears to have future Prospective for reduction in greenhouse gas emissions. Nevertheless, the development of such a technology requires appropriate infrastructures for production, Storage and refuelling stages in a refuelling station. This one presents safety challenges due to the hydrogen chemicophysical characteristics. So, to avoid hazards, it is necessary to implement safety practices that, if early adopted in the development of a fuelling station project, can allow very low impact, safety being incorporated in the project itself. However, a drawback is the not sufficient experience and the scarcity of the relevant data collection. To deepe…
Epistemic uncertainty in fault tree analysis approached by the evidence theory
2012
Abstract Process plants may be subjected to dangerous events. Different methodologies are nowadays employed to identify failure events, that can lead to severe accidents, and to assess the relative probability of occurrence. As for rare events reliability data are generally poor, leading to a partial or incomplete knowledge of the process, the classical probabilistic approach can not be successfully used. Such an uncertainty, called epistemic uncertainty, can be treated by means of different methodologies, alternative to the probabilistic one. In this work, the Evidence Theory or Dempster–Shafer theory (DST) is proposed to deal with this kind of uncertainty. In particular, the classical Fau…
Public transportation and fear of crime at BRT Systems: Approaching to the case of Barranquilla (Colombia) through integrated choice and latent varia…
2021
Abstract Security perception and Fear of Crime (FoC) in urban scenarios have the potential to affect travel behavior, changing people’s travel choices and patterns. In this sense, the feeling of being “safe” or “at-risk” in public transportation not only depends on observable factors like illumination, travel companionship or transport crowding, but also on unobservable individual-specific latent attributes, among which fear of crime constitutes a major issue to consider in transport security policy-making. This study aimed to describe the relationships among sociodemographic features, travel situations, system-design features, and the Fear of Crime at three different locations (buses, bus …
Economic Adaptation to Risky Environment in the Late Middle Ages: The Case of the "Accrues" of the Doubs in Chaussin (Jura, France) from c. 1370 to c…
2017
Located along the meanders of the Doubs, the people of Chaussin had to deal with the particular impact of the river on their environment. Due to the impact of the Little Ice Age on water levels in the area, the Doubs sometimes had special floods, which frequently changed its course from the end of the fourteenth century. As a result, some lands were absorbed, and others emerged, which were called the “accrues.” From 1377 the first observation of lost lands appears in the accounts of the castellan, in a petition from landowners who did not want to pay taxes on these fields. More than twenty years later, in the first decade of the fifteenth century, the duke of Burgundy, facing the same situa…