Search results for " Outcomes."

showing 10 items of 345 documents

Intrinsic Subtypes and Gene Expression Profiles in Primary and Metastatic Breast Cancer.

2017

Biological changes that occur during metastatic progression of breast cancer are still incompletely characterized. In this study, we compared intrinsic molecular subtypes and gene expression in 123 paired primary and metastatic tissues from breast cancer patients. Intrinsic subtype was identified using a PAM50 classifier and χ2 tests determined the differences in variable distribution. The rate of subtype conversion was 0% in basal-like tumors, 23.1% in HER2-enriched (HER2-E) tumors, 30.0% in luminal B tumors, and 55.3% in luminal A tumors. In 40.2% of cases, luminal A tumors converted to luminal B tumors, whereas in 14.3% of cases luminal A and B tumors converted to HER2-E tumors. We ident…

Mama -- Càncer -- Aspectes genètics0301 basic medicineCancer ResearchPathologyReceptor ErbB-2DiseaseTranscriptome0302 clinical medicineGene expressionSurvival outcomes Letrozole Concordance Predictor Disease Impact Brain Cells Women RiskSurvival outcomesDiseaseNeoplasm Metastasisskin and connective tissue diseasesRegulation of gene expressionAged 80 and overBrainCells WomenMiddle AgedPrognosisMetastatic breast cancerNeoplasm ProteinsGene Expression Regulation NeoplasticImpactOncology030220 oncology & carcinogenesisLetrozoleFemaleRiskAdultmedicine.medical_specialtymedicine.drug_classBreast NeoplasmsBiologyArticle03 medical and health sciencesBreast cancerConcordancemedicineBiomarkers TumorHumansGeneAgedEstrogensmedicine.disease030104 developmental biologyEstrogenNeoplasm Recurrence LocalTranscriptomePredictor
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Consumer-Generated Reviews on Social Media and Brand Relationship Outcomes in the Fast-Food Chain Industry

2017

A number of studies agree on the fact that social media users tend to trust more the contents created by other users than those generated by companies’ marketing departments or advertising agencies. However, little is known regarding whether social media can actually enhance brand trust and other brand relationship outcomes that are deemed critical to the hospitality marketing literature. This paper seeks to offer some important insight on this issue by examining the impact of consumer-generated reviews on social media on four main pillars of the relationship marketing paradigm, i.e., satisfaction, trust, commitment, and loyalty. The inter-relationship between brand outcomes is also examine…

Marketingbusiness.industryBrand awarenessBrand relationship outcomes consumer-generated reviews fast-food chain brands social media communication university students05 social sciencesAdvertisingCustomer relationship managementManagement Information SystemsBrand managementBrand relationshipTourism Leisure and Hospitality Management0502 economics and business050211 marketingSocial mediaBrand equityMarketingbusinessComputingMilieux_MISCELLANEOUS050203 business & managementIntegrated marketing communicationsConsumer behaviour
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Application of a self-learning methodology for the enhancement of the oral communication student outcome in International Business studies

2019

[EN] Effective oral communication is one of the most demanded student outcomes in the labour market, especially for degree students on International Business. Although this outcome is usually evaluated in several subjects along the curriculum, it is barely worked neither inside nor outside the classroom, mainly due to lack of time and to unavailability of proper learning methodologies. The PIMECOE project, an innovation and educational improvement project on this matter, has developed a self-learning methodology on the Effective Oral Communication student outcome, in which auto-diagnosis tests, selflearning tools and peer assessments are conveniently combined to enhance the proficiency leve…

Medical educationTECNOLOGIA DE ALIMENTOSESTADISTICA E INVESTIGACION OPERATIVAInternational businessOutcome (game theory)Matemàtica EnsenyamentOral skillsCiència EnsenyamentStudent outcomesOral communicationSelf-learning methodologiesCIENCIAS DE LA COMPUTACION E INTELIGENCIA ARTIFICIALORGANIZACION DE EMPRESASComputingMilieux_COMPUTERSANDEDUCATIONPeer assesmentsCOMPOSICION ARQUITECTONICAEnsenyament InnovacionsPsychologyLENGUAJES Y SISTEMAS INFORMATICOS
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Analysis of the main weaknesses of university students regarding the "effective oral communication" student outcome

2019

[EN] The "Effective oral communication" is one of the most demanded student outcomes in the workplace, since being a good communicator is essential in any field. Inefficient communication can lead to misinterpretations and erroneous conclusions. Therefore, it is a very important student outcome both in the university and in the workplace. The student or graduate must know how to communicate effectively, both orally and in writing, appropriately using the necessary resources and adapting to the characteristics of the situation and the audience. However, despite its importance, the disparity in the mastery level of the oral communication student outcome by students makes it difficult to work …

Medical educationTECNOLOGIA DE ALIMENTOSmedia_common.quotation_subjectESTADISTICA E INVESTIGACION OPERATIVAUniversitatsOutcome (game theory)Oral skillsStudent outcomesWork (electrical)Oral communicationSelf-learning methodologiesCIENCIAS DE LA COMPUTACION E INTELIGENCIA ARTIFICIALComputingMilieux_COMPUTERSANDEDUCATIONORGANIZACION DE EMPRESASQuality (business)COMPOSICION ARQUITECTONICAPsychologyLENGUAJES Y SISTEMAS INFORMATICOSmedia_common
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Does Replacing Face-to-face Lectures with Pre-recorded Video Lectures Affect Learning Outcomes?

2019

Videoing lectures have been popular during the past decade. The literature on the effect of video lectures is controversial. Some studies indicate that video lectures have a positive effect on learning outcomes and student satisfaction, while some state that there is no effect at all. In this paper, we share the results of a university undergraduate course, where half of the lectures were replaced by pre-recorded lectures. The results indicate that using pre-recorded lectures had a statistically significant positive effect on grades. Also, the students’ satisfaction levels were higher. peerReviewed

Medical educationnettivideotopiskelijatstudent satisfactioneducationAffect (psychology)opetusoppimistuloksetvideo lecturesvideoluennotlearning outcomesFace-to-facetyytyväisyysComputingMilieux_COMPUTERSANDEDUCATIONPsychology
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Changes in Mental Health of Children and Young People in Residential Care: Outcomes and Associated Factors

2023

Several studies have evidenced that children in out-of-home care (OOHC), including foster family care and residential care, reveal high levels of mental health disorders (ranging from 40% to 88%). This study examines the outcomes in mental health reported by key residential workers in a group of children and youth (N = 492) between 8-17 years old who were in residential child care (RCC) in Spain. The research also aims to explore the relationship between mental health outcomes and the provision of mental health services (i.e., receiving any mental health treatment) as well as the influence of child, family, and placement factors. The design of this study includes two measures: a baseline (T…

Mental health outcomesSocial PsychologyResidential child careDevelopmental and Educational PsychologyMental health treatmentMental healthApplied PsychologyPsychosocial Intervention
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Early Development of the Gut Microbiota and Immune Health

2014

In recent years, the increase in human microbiome research brought about by the rapidly evolving “omic” technologies has established that the balance among the microbial groups present in the human gut, and their multipronged interactions with the host, are crucial for health. On the other hand, epidemiological and experimental support has also grown for the ‘early programming hypothesis’, according to which factors that act in utero and early in life program the risks for adverse health outcomes later on. The microbiota of the gut develops during infancy, in close interaction with immune development, and with extensive variability across individuals. It follows that the specific process of…

Microbiology (medical)atopylcsh:MedicineReviewDiseaseinfant gutBiologyGut floraHealth outcomesantibioticsImmune systemHuman gutImmunology and Allergyearly programmingmicrobe-host interactionsMolecular BiologyGut colonizationIntrauterine transmissionnecrotizing enterocolitisgut microbiotaGeneral Immunology and Microbiologylcsh:RHuman microbiomehuman microbiomebiology.organism_classificationintrauterine transmissionInfectious DiseasesImmunologyimmune diseasePathogens
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Human Immunodeficiency Virus Infection and Diverse Physical Health Outcomes: An Umbrella Review of Meta-analyses of Observational Studies.

2019

Abstract Background Our aim was to assess both the credibility and strength of evidence arising from systematic reviews with meta-analyses of observational studies and physical health outcomes associated with human immunodeficiency virus (HIV) but not acquired immunodeficiency syndrome. Methods We performed an umbrella review of observational studies. Evidence was graded as convincing, highly suggestive, suggestive, weak, or nonsignificant. Results From 3413 studies returned, 20 were included, covering 55 health outcomes. Median number of participants was 18 743 (range 403–225 000 000). Overall, 45 (81.8%) of the 55 unique outcomes reported nominally significant summary results (P < .05). O…

Microbiology (medical)medicine.medical_specialtyPopulationcomorbidHIV InfectionsDisease03 medical and health sciencesPulmonary Disease Chronic Obstructive0302 clinical medicineAcquired immunodeficiency syndrome (AIDS)Meta-Analysis as TopicPre-EclampsiaPregnancyInternal medicineMedicineHumanshealth outcomes030212 general & internal medicineeducationArticles and CommentariesCOPDeducation.field_of_studyhuman immunodeficiency virusumbrella reviewbusiness.industryhuman immunodeficiency viruPublic healthIncidence (epidemiology)IncidenceAn Umbrella Review of Meta-analyses of Observational Studies.- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2019 [Grabovac I. Veronese N. Stefanac S. Haider S. Jackson S. Koyanagi A. Meilinger M. Stubbs B. Firth J. Soysal P. et al. -Human Immunodeficiency Virus Infection and Diverse Physical Health Outcomes]HIVmedicine.diseaseComorbidityObservational Studies as TopicInfectious DiseasesCross-Sectional StudiesAcademicSubjects/MED00290health outcomeFemalebusiness030217 neurology & neurosurgeryCohort studySystematic Reviews as TopicClinical infectious diseases : an official publication of the Infectious Diseases Society of America
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Reading and math abilities of Finnish school beginners born very preterm or with very low birth weight

2017

Reading and math skills of preterm born (birth weight 1500 g or gestational age:532 weeks) children and full term (FT) children were compared during the first weeks of grade 1. The participants were 194 preterm born and 175 FT children born between 2001 and 2006. There were more precocious readers among FT than among preterm students, but even the latter performed close to the national norm. FT and preterm group differences among non-readers were minor with only rapid naming showing a robust difference. Math performance showed a stable difference in favor of FT students and the difference was sustained in the full-scale IQcontrol. Major brain pathology increased the likelihood of poor schol…

NEUROBEHAVIORAL OUTCOMESSocial Psychology515 PsychologyBirth weightNEUROPSYCHOLOGICAL OUTCOMESeducationVery low birth weightAcademic achievement3124 Neurology and psychiatryEducationDevelopmental psychology03 medical and health sciencesPREREADING SKILLS0302 clinical medicine3123 Gynaecology and paediatrics030225 pediatricsACADEMIC-ACHIEVEMENTDevelopmental and Educational PsychologymedicineCognitive developmentVery Preterm Birthta516AUTOMATIZED NAMING RANta5154. Educationta118405 social sciences3112 Neurosciences050301 educationGestational agepreterm birthbirth weightLEARNING-DISABILITIESLow birth weightmath skillsCOGNITIVE-DEVELOPMENTLearning disabilityRISK-FACTORSGestationreading skillsschool readinessmedicine.symptomFOLLOW-UPPsychologyCHILDREN BORN0503 educationVery preterm birthLearning and Individual Differences
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Predictors of oncological outcomes in T1G3 patients treated with BCG who undergo radical cystectomy

2018

PURPOSE: To evaluate the oncological impact of postponing radical cystectomy (RC) to allow further conservative therapies prior to progression in a large multicentre retrospective cohort of T1-HG/G3 patients initially treated with BCG. METHODS: According to the time of RC, the population was divided into 3 groups: patients who did not progress to muscle-invasive disease, patients who progressed before radical cystectomy and patients who experienced progression at the time of radical cystectomy. Clinical and pathological outcomes were compared across the three groups. RESULTS: Of 2451 patients, 509 (20.8%) underwent RC. Patients with tumors > 3 cm or with CIS had earlier cystectomies (HR = 1…

NephrologyMalemedicine.medical_treatment030232 urology & nephrologyKaplan-Meier EstimateSettore MED/24 - UrologiaCohort Studies0302 clinical medicineRetrospective StudieMultivariate AnalysiOutcomeeducation.field_of_studyHigh riskBladder cancerMiddle AgedPrognosisEditorialTreatment OutcomeLocal030220 oncology & carcinogenesisBCG VaccineFemaleSurvival AnalysiBladder cancer; Cystectomy; Extravesical disease; High risk; Outcomes; T1G3; UrologyHumanmedicine.medical_specialtyPrognosiUrologyPopulationUrologyOutcomesT1G3CystectomyRisk AssessmentDisease-Free SurvivalCystectomy03 medical and health sciencesAll institutes and research themes of the Radboud University Medical CenterInternal medicineUrological cancers Radboud Institute for Molecular Life Sciences [Radboudumc 15]medicineHumansNeoplasm InvasivenesseducationSurvival analysisProportional Hazards ModelsRetrospective StudiesAgedNeoplasm StagingNeoplasm InvasiveneCarcinoma Transitional CellBladder cancerbusiness.industryProportional hazards modelBladder cancer; Cystectomy; Extravesical disease; High risk; Outcomes; T1G3; Aged; BCG Vaccine; Carcinoma Transitional Cell; Cohort Studies; Cystectomy; Disease-Free Survival; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Neoplasm Invasiveness; Neoplasm Recurrence Local; Neoplasm Staging; Prognosis; Proportional Hazards Models; Retrospective Studies; Risk Assessment; Survival Analysis; Treatment Outcome; Urinary Bladder NeoplasmsCarcinomaRetrospective cohort studymedicine.diseaseSurvival AnalysisNeoplasm RecurrenceUrinary Bladder NeoplasmsConcomitantMultivariate AnalysisProportional Hazards ModelTransitional CellCohort StudieNeoplasm Recurrence LocalbusinessExtravesical disease
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