Search results for " PAI."
showing 10 items of 3604 documents
Application of FTIR Spectroscopy to Analyze RNA Structure
2020
Fourier transform infrared (FTIR) spectroscopy has been widely used for the analysis of both protein and nucleic acid secondary structure. This is one of the vibration spectroscopy methods that are extremely sensitive to any change in molecular structure. While numerous reports describe how to proceed to analyze protein and deoxyribonucleic acid (DNA) structures using FTIR, reports related to the analyses of ribonucleic acids (RNAs) are few. Nevertheless, RNAs are versatile molecules involved in a multitude of roles in the cell. In this chapter, we present applications of FTIR for the structural analysis of RNA, including the analysis of helical parameters and noncanonical base pairing, oft…
In Defense of Sympathy, in Consideration of Empathy, and in Praise of Compassion: A History of the Present.
2017
Vibroacoustic treatment for chronic pain and mood disorders in a specialized healthcare setting
2017
Much of what we know about vibroacoustic treatment and its efficacy has been published in case reports. Recent clinical trials have increased awareness and understanding of this treatment for people with Parkinson’s disease or Fibromyalgia Syndrome. There are no standardized protocols for using vibroacoustic treatment although research has focused on using 40Hz. The rehabilitation unit of [blinded] Central Hospital in [blinded] has used vibroacoustic treatment for more than two decades as part of specialized healthcare in the [blinded] healthcare district. Patient responses have been recorded using Visual Analog Scales showing positive outcomes on several measures including pain and mood. T…
Place names as evocative elements of historical landscape. Analysis of urban place names in the Vinalopó Basin
2017
La cuenca del Vinalopó, al sur del País Valenciano, está compuesta por una serie de comarcas industriales densamente pobladas que han sido habitadas desde la Antigüedad. Aprovechando la perspectiva diacrónica que ofrecen los nombres de lugar, se reconstituyen virtualmente ciertos elementos naturales y culturales del paisaje histórico de la comarca del Vinalopó mediante un análisis toponímico basado en elucidar la etimología de los nombres de lugar, en el método de observación de los rasgos geográficos de dichos lugares y en las fuentes históricas que se refieren a los mismos. The Vinalopó basin, in the south of the Valencian Community (Spain), is composed of densely populated industrial tow…
Thérapie d’acceptation et d’engagement (ACT) et Mindfulness, un modèle de flexibilité psychologique pour la douleur chronique
2016
Resume La therapie d’acceptation et d’engagement (ACT) et la meditation en pleine conscience appelee egalement Mindfulness sont issues de la troisieme vague des therapies comportementales et cognitives (TCC). Bien que ces therapies aient suscite l’interet des cliniciens et chercheurs internationaux et qu’elles beneficient a present de solides supports empiriques appliques au domaine de la douleur chronique, l’ACT et le Mindfulness restent encore meconnus en France et encore trop peu utilises pour reduire la souffrance des patients douloureux chroniques. Nous presenterons, dans cet article, les concepts theoriques de la therapie d’ACT et du Mindfluness, illustres d’exemples cliniques, mais e…
Indexing epistemic incongruence: uy as a formal sign of disagreement in agreement sequences in Spanish
2018
Abstract This study explores epistemic incongruence in Spanish by focusing on the particle uy in Iberian Spanish. It is claimed that this interjection has a basic change-of-state meaning and that it is commonly used to stress disagreement. Despite its general association to disagreement, the particle can be used in agreeing responses, where it also treats the previous turn as problematic. In this sequential environment, however, it is not the content of the previous turn but rather the underlying assumptions (the basic epistemic configuration of an assertion-answer adjacency pair) that are challenged by the second speaker. The evidence for this analysis comes from the sequential context. Ty…
Korpusonomastinen tutkimus slanginimistä Hesa ja Stadi digitaalisissa diskursseissa
2019
Artikkelissamme selvitämme Helsinkiä tarkoittavien slanginimien, Hesan ja Stadin, käyttöä uudentyyppisen aineiston ja menetelmän avulla. Aiemmissa näitä nimiä koskevissa tutkimuksissa lähtökohta on ollut kvalitatiivinen, mutta tässä tutkimuksessa lähdemme liikkeelle laajasta digitaalisesta aineistosta ja tilastollisista menetelmistä. Tutkimuksemme on uusi avaus nimistöntutkimuksessa, ja nimitämme sitä korpusavusteiseksi nimistöntutkimukseksi, lyhyemmin korpusonomastiikaksi.
 Aineistonamme on laaja Suomi24-keskustelufoorumista muodostettu ja Kielipankista saatava Suomi24-korpus, josta olemme hakeneet Hesa- ja Stadi-nimet. Tutkimus toteutetaan korpusavusteisena diskurssintutkimuksena. Mo…
Can copper(II) mediate Hoogsteen base-pairing in a left-handed DNA duplex? A pulse EPR study
2010
Pulse EPR spectroscopy is sued to investigate possible structural features of the copper(II) ion coordinated to poly(dG-dC) poly(dG-dC) in a frozen aqueous solution, and the structural change of the polynucleotide induced by the presence of the metal ion. Two different copper species were identified and their geometry explained by a molecular model. According to this model, one species is exclusively coordinated to a single guanine with the N7 nitrogen atom forming a coordinative bond with the copper. In the other species, a guanine and a cytosine form a ternary complex together with the copper ion. A copper crosslink between the N7 of guanine and N3 of cytosine is proposed as the most prob…
Evidence for the production of three massive vector bosons with the ATLAS detector
2019
A search for the production of three massive vector bosons in proton–proton collisions is performed using data at TeV recorded with the ATLAS detector at the Large Hadron Collider in the years 2015–2017, corresponding to an integrated luminosity of 79.8 fb−1. Events with two same-sign leptons ℓ (electrons or muons) and at least two reconstructed jets are selected to search for . Events with three leptons without any same-flavour opposite-sign lepton pairs are used to search for , while events with three leptons and at least one same-flavour opposite-sign lepton pair and one or more reconstructed jets are used to search for . Finally, events with four leptons are analysed to search for and .…
Constraints on off-shell Higgs boson production and the Higgs boson total width in ZZ → 4ℓ and ZZ → 2ℓ2ν final states with the ATLAS detector
2018
A measurement of off-shell Higgs boson production in the and decay channels, where ℓ stands for either an electron or a muon, is performed using data from proton–proton collisions at a centre-of-mass energy of TeV. The data were collected by the ATLAS experiment in 2015 and 2016 at the Large Hadron Collider, and they correspond to an integrated luminosity of . An observed (expected) upper limit on the off-shell Higgs signal strength, defined as the event yield normalised to the Standard Model prediction, of 3.8 (3.4) is obtained at 95% confidence level (CL). Assuming the ratio of the Higgs boson couplings to the Standard Model predictions is independent of the momentum transfer of the Higgs…