Search results for " PEG"
showing 10 items of 88 documents
Percutaneous endoscopic gastrostomy in amyotrophic lateral sclerosis
2011
Background: Percutaneous endoscopic gastrostomy (PEG) is offered to amyotrophic lateral sclerosis (ALS) patients with severe dysphagia. Immediate benefits of PEG are adequate food intake and weight stabilization. However, the impact of PEG on survival is still uncertain. In this work we retrospectively evaluated the effect of PEG on survival in a cohort of ALS patients followed in a tertiary referral centre. Methods: Between 2000 and 2007, 150 dysphagic ALS patients were followed until death or tracheostomy. PEG was placed in 76 patients who accepted the procedure and survival was analysed using the Kaplan-Meier life-table method. Results: In ALS patients submitted to PEG, no major complica…
La Tavola e il Monte di Pietà di Palermo tra crisi e sperimentazione (1778-1799)
2011
Il sistema delle reti di credito che alimenta il mercato finanziario siciliano entra in stallo nella seconda metà del ‘700 quando si consuma la crisi istituzionale e gestionale non solo delle Tavole di Palermo e di Messina, ma anche dei Monti di Pietà. Un momento di transizione che può essere interpretato coniugando il concetto di “crisi” con quello di “sperimentazione”, poiché il “sistema” tenta di trovare soluzioni più efficienti per adeguare gli istituti esistenti alle nuove esigenze del mercato. Una “sperimentazione” che, ad esempio, spinge la Tavola di Palermo a istituire una sezione specializzata per sostenere i produttori di frumento grazie all’erogazione di crediti su pegno. Tentati…
Boceprevir is highly effective in treatment-experienced hepatitis C virus-positive genotype-1 menopausal women
2014
AIM: To investigate the safety/efficacy of Boceprevirbased triple therapy in hepatitis C virus (HCV)-G1 menopausal women who were historic relapsers, partial-responders and null-responders. METHODS: In this single-assignment, unblinded study, we treated fifty-six menopausal women with HCV-G1, 46% F3-F4, and previous PEG-α/RBV failure (7% null, 41% non-responder, and 52% relapser) with 4 wk lead-in with PEG-IFNα2b/RBV followed by PEGIFNα2b/RBV+Boceprevir for 32 wk, with an additional 12 wk of PEG-IFN-α-2b/RBV if patients were HCV-RNA-positive by week 8. In previous null-responders, 44 wk of triple therapy was used. The primary objective of retreatment was to verify whether a sustained virolo…
IL28B CC GENOTYPE IS ASSOCIATED WITH HIGHER ON-TREATMENT-RESPONSE RATES IN PTS WITH HCV-3: INTERIM RESULTS OF THE WRITE STUDY
2012
LITIS AESTIMATIO E ACTIO PIGNERATICIA IN REM. A PROPOSITO DI D. 20.1.21.3
2006
La ricerca si incentra sull' interpretazione di due testimonianze, D. 20.1.21.3. e D. 20.1.16.3, in matera di indiduazione del criterio di determinazione della litis aestimatio nell'actio in rem a tutela del diritto di pegno. L'autore dimostra che, a partire dalla piena eta' classica e certamente con Ulpiano, il valore della cosa pignorata ed il valore del credito garantito non furono mai alternativamente considerati idonei a fungere da criteri di determinazione della litis aestimatio a seconda delle diverse circostanze nelle quali l'azione fosse stata esperita. Il criterio fu sempre costituito dal valore del credito garantito. Un'eventuale maggiorazione rispetto a tale valore si sarebbe po…
Pegylated liposomal doxorubicin (PLD) and weekly paclitaxel (P) as second line chemotherapy in metastatic bladder cancer.
2008
Inulin vinyl sulfone derivative cross-linked with bis-amino PEG: new materials for biomedical applications
2009
In this work new hydrogels based on biocompatible polymers such as inulin (INU) and O,O'-bis(2-aminoethyl)polyethyleneglycol (PEGBa) have been prepared and charaterized. In particular, INU has been derivatized with divinyl sulfone (DV) thus obtaining the INUDV derivative, a copolymer bearing double bonds highly reactive towards the conjugate addition by nucleophilic molecules. INUDV has been characterized by FT-IR, 1 H-NMR and SEC analyses that have confirmed the success of the derivatization reaction. With the aim to obtain novel hydrogel systems, INUDV derivative has been cross-linked with PEGBa in phosphate buffer solution pH 7.4. The reaction has been carried out for 4 h at room tempera…
On the morphology of Anisakis pegreffii: a comparative analysis of three microscopic techniques used to build a new parasite atlas
2014
BACKGROUND: Human anisakidosis is a parasitic anthropozoonosis caused by larval nematodes of the family Anisakidae. Here, we report a detailed description of the morphology of Anisakis pegreffii third-stage larva performed using a conventional light and confocal microscopy, and scanning electron microscopy (SEM) that provide a basis for both phenotypic studies and genetic mutations. METHODS: The collected larvae from fish were morphologically identified as Anisakis larvae Type I, and they were characterized by PCR-RFLP to identify the Anisakis pegreffii specie. Using NC5/NC2 primers, ribosomal genomic regions ITS1, 5.8 SrRNA and ITS2 of DNA were amplified and PCR products were sequenced. Fi…
Synthesis and characterization of poly(L,L-lactide)-b-polyethylene glycol) diblock copolymers as plasticizers and their effect on the hydrophilicity …
2011
Oral lichen planus after certolizumab pegol treatment in a patient with Crohn's disease
2011
Dear Sir , Lichen planus (LP) is a relatively uncommon inflammatory dermatosis of the mucocutaneous surfaces that can present with a variety of clinical manifestations and, most commonly, affecting middle-aged adults. The disease course may be short or chronic, although most cases may resolve after 1 month to 7 years. The real prevalence of LP is unknown, but is estimated to be 1% in the USA.1 The pathogenesis of LP is not entirely understood. In general, activated T lymphocytes are recruited to the dermal–epidermal junction and induce apoptosis in basal keratinocytes. Both CD4+ and CD8+ T lymphocytes are found in the lichenoid infiltrate of LP, with a predominance of the latter cell type b…