Search results for " PP"
showing 10 items of 105 documents
A role for the peroxisomal 3-ketoacyl-CoA thiolase B enzyme in the control of PPARα-mediated upregulation of SREBP-2 target genes in the liver.: ThB …
2011
International audience; Peroxisomal 3-ketoacyl-CoA thiolase B (Thb) catalyzes the final step in the peroxisomal β-oxidation of straight-chain acyl-CoAs and is under the transcription control of the nuclear hormone receptor PPARα. PPARα binds to and is activated by the synthetic compound Wy14,643 (Wy). Here, we show that the magnitude of Wy-mediated induction of peroxisomal β-oxidation of radiolabeled (1-(14)C) palmitate was significantly reduced in mice deficient for Thb. In contrast, mitochondrial β-oxidation was unaltered in Thb(-/-) mice. Given that Wy-treatment induced Acox1 and MFP-1/-2 activity at a similar level in both genotypes, we concluded that the thiolase step alone was respons…
A novel multi-wavelength procedure for blood pressure estimation using opto-physiological sensor at peripheral arteries and capillaries
2018
© 2018 SPIE. In this study, the Carelight multi-wavelength opto-electronic patch sensor (OEPS) was adopted to assess the effectiveness of a new approach for estimating the systolic blood pressure (SBP) through the changes in the morphology of the OEPS signal. Specifically, the SBP was estimated by changing the pressure exerted on an inflatable cuff placed around the left upper arm. Pressure acquisitions were performed both with gold standard (i.e. electronic sphygmomanometer), and Carelight sensor (experimental procedure), on subjects from a multiethnic cohort (aged 28 ± 7). The OEPS sensor was applied together with a manual inflatable cuff, going slightly above the level of the SBP with in…
Taking advantage of the functional synergism between carbon nanotubes and graphene nanoplatelets to obtain polypropylene-based nanocomposites with en…
2020
Carbon Nanotubes (CNT) and Graphene Nanoplatelets (GNP) were incorporated in Polypropylene (PP) as single filler (CNT=1, 2 and 4 %wt. and GNP=2, 4, and 6 %wt.) and in hybrid form (CNT:GNP weight ratio 2:2, 2:4 and 4:2) using a prototype miniature Twin Screw Extruder (TSE) coupled with a double slit rheological die, in order to assess in-line the extent of nanofiller dispersion and to deliver PP-based nanocomposites with enhanced thermo-oxidative stability. The morphological, electrical and mechanical properties, as well as the resistance to thermal and photo degradation of the composites containing single nanofillers (PP/CNT and PP/GNP) were compared with those of hybrid PP based nanocompos…
Machine-readable entailments with the Italian 'prendere' construction expressing hitting and insulting events
2022
The Italian language features a little debated transitive construction with prendere ‘to take/to catch’ in which a prepositional phrase (PP) with an adverbial value occurs mandatorily (e.g. Lui prese a pugni Leo ‘He punched Leo’). Semantically, this construction often implies the use of physical force or verbal offence. In the hitting or insulting event, the notional subject generally is a [+ Human] Agent, whilst the notional direct object generally is a [+ Animate] Affectee ([1]: 4). It can be contended that prendere, which carries no literal meaning, is zero-valent and that the predicate assigning semantic roles is the PP. A computational tool will be illustrated, …
Complete sequencing of Novosphingobium sp. PP1Y reveals a biotechnologically meaningful metabolic pattern.
2014
Background Novosphingobium sp. strain PP1Y is a marine α-proteobacterium adapted to grow at the water/fuel oil interface. It exploits the aromatic fraction of fuel oils as a carbon and energy source. PP1Y is able to grow on a wide range of mono-, poly- and heterocyclic aromatic hydrocarbons. Here, we report the complete functional annotation of the whole Novosphingobium genome. Results PP1Y genome analysis and its comparison with other Sphingomonadal genomes has yielded novel insights into the molecular basis of PP1Y’s phenotypic traits, such as its peculiar ability to encapsulate and degrade the aromatic fraction of fuel oils. In particular, we have identified and dissected several highly …
Search for displaced vertices arising from decays of new heavy particles in 7 TeV pp collisions at ATLAS
2012
We present the results of a search for new, heavy particles that decay at a significant distance from their production point into a final state containing charged hadrons in association with a high-momentum muon. The search is conducted in a pp-collision data sample with a center-of-mass energy of 7 TeV and an integrated luminosity of 33 pb[superscript −1] collected in 2010 by the ATLAS detector operating at the Large Hadron Collider. Production of such particles is expected in various scenarios of physics beyond the standard model. We observe no signal and place limits on the production cross-section of supersymmetric particles in an R-parity-violating scenario as a function of the neutral…
Search for CP violation in D (+/-) -> (KSK +/-)-K-0 and D-s(+/-) -> K-S(0)pi(+/-) decays
2014
A search for \CP violation in Cabibbo-suppressed $D^{\pm}\rightarrow K^0_{\mathrm{S}} K^{\pm}$ and $D^{\pm}_{s}\rightarrow K^0_{\mathrm{S}} \pi^{\pm}$ decays is performed using $pp$ collision data, corresponding to an integrated luminosity of 3~fb$^{-1}$, recorded by the LHCb experiment. The individual $CP$-violating asymmetries are measured to be \begin{eqnarray*} \mathcal{A}_{CP}^{D^{\pm}\rightarrow K^0_{\mathrm{S}} K^{\pm}} & = & (+0.03 \pm 0.17 \pm 0.14) \% \mathcal{A}_{CP}^{D^{\pm}_{s}\rightarrow K^0_{\mathrm{S}} \pi^{\pm}} & = & (+0.38 \pm 0.46 \pm 0.17) \%, \end{eqnarray*} assuming that $CP$ violation in the Cabibbo-favoured decays is negligible. A combination of the measured asymmet…
New molecular targets in bone metastases.
2010
Bone metastases have a major impact on morbidity and on mortality in cancer patients. Despite its clinical relevance, metastasis remains the most poorly elucidated aspect of carcinogenesis. The biological mechanisms leading to bone metastasis establishment have been referred as " vicious circle," a complex network between cancer cells and the bone microenvironment. This review is aimed to underline the new molecular targets in bone metastases management other than bisphosphonates. Different pathways or molecules such as RANK/RANKL/OPG, cathepsin K, endothelin-1, Wnt/DKK1, Src have recently emerged as potential targets and nowadays preclinical and clinical trials are underway. The results fr…
Thermo-hygrometric comfort in the lecture hall of a library: methodology and experimental evidence.
2012
The present study verifies the thermo hygrometric comfort conditions in subjects of a university library users, evaluating the differences and peculiarities in the data collected at the measurement campaign. Particularities of the investigation is the period studied concerning the time frame of the Middle season, which is not expected to power the air conditioning systems. Based on assumptions on the thermal resistance of clothing in the spring and the metabolic type of subjects, the environmental parameters were monitored in some work position in the reading hall in the library of the Faculty of Medicine and Surgery of the University of Palermo. The article presents analyses of the measure…
Measurement of Upsilon production in collisions at root s=2.76 TeV
2014
The production of Υ(1S) , Υ(2S) and Υ(3S) mesons decaying into the dimuon final state is studied with the LHCb detector using a data sample corresponding to an integrated luminosity of 3.3pb-1 collected in proton–proton collisions at a centre-of-mass energy of s=2.76 TeV. The differential production cross-sections times dimuon branching fractions are measured as functions of the Υ transverse momentum and rapidity, over the ranges pT<15 GeV/ c and 2.0<y<4.5 . The total cross-sections in this kinematic region, assuming unpolarised production, are measured to be σpp→Υ(1S)X×BΥ(1S)→μ+μ-=1.111±0.043±0.044nb,σpp→Υ(2S)X×BΥ(2S)→μ+μ-=0.264±0.023±0.011nb,σpp→Υ(3S)X×BΥ(3S)→μ+μ-=0.159±0.020±0.…