Search results for " PREDICTION"
showing 10 items of 366 documents
Comparison of genetic risk prediction models to improve prediction of coronary heart disease in two large cohorts of the MONICA/KORA study
2021
Abstract It is still unclear how genetic information, provided as single‐nucleotide polymorphisms (SNPs), can be most effectively integrated into risk prediction models for coronary heart disease (CHD) to add significant predictive value beyond clinical risk models. For the present study, a population‐based case‐cohort was used as a trainingset (451 incident cases, 1488 noncases) and an independent cohort as testset (160 incident cases, 2749 noncases). The following strategies to quantify genetic information were compared: A weighted genetic risk score including Metabochip SNPs associated with CHD in the literature (GRSMetabo); selection of the most predictive SNPs among these literature‐co…
Frailty Scales for Prognosis Assessment of Older Adult Patients after Acute Myocardial Infarction
2021
We aimed to compare the prognostic value of two different measures, the Fried’s Frailty Scale (FFS) and the Clinical Frailty Scale (CFS), following myocardial infarction (MI). We included 150 patients ≥ 70 years admitted from AMI. Frailty was evaluated on the day before discharge. The primary endpoint was number of days alive and out of hospital (DAOH) during the first 800 days. Secondary endpoints were mortality and a composite of mortality and reinfarction. Frailty was diagnosed in 58% and 34% of patients using the FFS and CFS scales, respectively. During the first 800 days 34 deaths and 137 admissions occurred. The number of DAOH decreased significantly with increasing scores of both FFS…
A Robustness Approach to Reliability
2012
Reliability of products is here regarded with respect to failure avoidance rather than probability of failure. To avoid failures, we emphasize variation and suggest some powerful tools for handling failures due to variation. Thus, instead of technical calculation of probabilities from data that usually are too weak for correct results, we emphasize the statistical thinking that puts the designers focus on the critical product functions. Making the design insensitive to unavoidable variation is called robust design and is handled by (i) identification and classification of variation, (ii) design of experiments to find robust solutions, and (iii) statistically based estimations of proper safe…
Initial conditions in AA and pA collisions
2016
A full understanding of the spacetime evolution of the QCD matter created in a heavy ion collision requires understanding the properties of the initial stages. In the weak coupling picture these are dominated by classical gluon fields, whose properties can also be studied via the scattering of dilute probes off a high energy hadron or nucleus. A particular challenge is understanding small systems, where LHC data is also showing signs of collective behavior. We discuss some recent results of on the initial matter production and thermalization in heavy ion collisions, in particular in the gluon saturation framework.
Energy dependence of event shapes and of $\alpha_s$ at LEP 2
1999
Infrared and collinear safe event shape distributions and their mean values are determined using the data taken at five different centre of mass energies above M-Z with the DELPHI detector at LEP. From the event shapes, the strong coupling alpha(s) is extracted in O(alpha(s)(2)), NLLA and a combined scheme using hadronisation corrections evaluated with fragmentation model generators as well as using an analytical power ansatz. Comparing these measurements to those obtained at M-Z, the energy dependence (running) of alpha(s) is accessible. The logarithmic energy slope of the inverse strong coupling is measured to be d alpha(s)(-1)/d log(E-cm) = 1.39 +/- 0.34 (stat) +/- 0.17(syst), in good ag…
Fermion pair production in e+e- collisions at 189-209 GeV and constraints on physics beyond the Standard Model
2006
Cross sections, angular distributions and forward-backward asymmetries are presented, of two-fermion events produced in e+e- collisions at centre-of-mass energies from 189 to 209 GeV at LEP, measured with the ALEPH detector. Results for e+e-, mu+mu-, tau+tau-, qq, bb and cc production are in agreement with the Standard Model predictions. Constraints are set on scenarios of new physics such as four-fermion contact interactions, leptoquarks, Z' bosons, TeV-scale quantum gravity and R-parity violating squarks and sneutrinos.
The Z boson spin observables as messengers of new physics
2017
We demonstrate that the 8 multipole parameters describing the spin state of the $Z$ boson are able to disentangle known $Z$ production mechanisms and signals from new physics at the LHC. They can be extracted from appropriate asymmetries in the angular distribution of lepton pairs from the $Z$ boson decay. The power of this analysis is illustrated by (i) the production of $Z$ boson plus jets; (ii) $Z$ boson plus missing transverse energy; (iii) $W$ and $Z$ bosons originating from the two-body decay of a heavy resonance.
A mathematical approach to predict the solids concentration in anaerobic membrane bioreactos (AnMBR): Evaluation of the volatile solids solubilization
2020
[EN] Anaerobic Membrane Bioreactors (AnMBR) are gaining attention as a suitable approach for sustainable low-strength wastewater treatment, as they bring together the advantages of both anaerobic treatments and membrane bioreactors. However, increasing the sludge retention time (SRT) necessary to favor hydrolysis increases the suspended solids concentration potentially leading to decreased permeate flux. Therefore, the availability of a mathematical approach to predict the solids concentration within an AnMBR can be very useful. In this work, a mathematical model describing the volatile solids concentration within the reactor as a function of the operating parameters and the influent charac…
Validity of needle core biopsy in the histological characterisation of mammary lesions
2006
Summary Over the last few years, there has been an enormous increase in the use of needle core biopsy (CB) for the histopathological characterisation of suspect lesions of the breast. The aim of this study was to verify the diagnostic reliability of CB by comparing the histological results obtained with the use of this technique with those obtained from the whole of the surgically resected specimen. We studied 198 out of 426 patients with clinically and/or radiologically suspect breast lesions. We found correspondence between the histological examination of the whole of the excised specimen and that of the CB in 94.9% of the cases of infiltrating carcinoma and in 71.4% of those involving du…