Search results for " PROGRESS"
showing 10 items of 1287 documents
Technology Diffusion, Worker Mobility and the Returns to Skill
2015
In this paper I illustrate how the diffusion across firms of a skill-neutral technology leads to a skill-biased impact on the economy. The model identifies (i) differences in inter-firm mobility between skill groups, (ii) productivity dispersion across firms within industries, and (iii) differences in wages between small and large firms as key determinants of the skill premium. Calibrated to match differences in inter-firm mobility between skill groups and rising productivity dispersion across firms, the model ascribes one-third of the sharp increase in the skill premium in U.S. manufacturing from 1977 to 1997 to skill-neutral technical progress and the technology diffusion process itself. …
X-Linked myopathy with excessive autophagy: A new hereditary muscle disease
1988
We report on 3 brothers with a myopathy that also affected their maternal grandfather and great-uncle. Characteristic features are onset in early childhood, very slow progression, normal life expectancy, weakness of proximal limb muscles, especially in the legs, elevation of serum creatine kinase, and no cardiac or intellectual involvement. In biopsy material muscle fibers are almost never necrotic but show excessive autophagic activity and exocytosis of the phagocytosed material. We suggest that this family has an undescribed type of congenital myopathy, for which we propose the name X-linked myopathy with excessive autophagy.
Nouvelles méthodes de traitement de signaux multidimensionnels par décomposition suivant le théorème de Superposition de Kolmogorov
2010
The processing of multidimensional signal remains difficult when using monodimensional-based methods. Therefore, it is either required to extend monodimensional methods to several dimensions, which is not always possible, or to convert the multidimensional signals into 1D signals. In this case, the priority is to preserve most of the properties of the original signal. In this context, the Kolmogorov Superposition Theorem offers a promising theoretical framework for multidimensional signal conversion. In 1957, Kolmogorov demonstrated that any multivariate function can be written as sums and compositions of monovariate functions.We have focused on the image decomposition according to the supe…
À propos du rock progressif : étiquetages, histoires, mise en spectacle et transformations du rock
2018
International audience
A novel homologous model for noninvasive monitoring of endometriosis progression.
2017
To date, several groups have generated homologous models of endometriosis through the implantation of endometrial tissue fluorescently labeled by green fluorescent protein (GFP) or tissue from luciferase-expressing transgenic mice into recipient animals, enabling noninvasive monitoring of lesion signal. These models present an advantage over endpoint models, but some limitations persist; use of transgenic mice is laborious and expensive, and GFP presents poor tissue penetration due to the relatively short emission wavelength. For this reason, a homologous mouse model of endometriosis that allows in vivo monitoring of generated lesions over time and mimics human lesions in recipient mice wou…
Positioning the principles of precision medicine in care pathways for allergic rhinitis and chronic rhinosinusitis â A EUFOREA-ARIA-EPOS-AIRWAYS IC…
2017
Precision medicine (PM) is increasingly recognized as the way forward for optimizing patient care. Introduced in the field of oncology, it is now considered of major interest in other medical domains like allergy and chronic airway diseases, which face an urgent need to improve the level of disease control, enhance patient satisfaction and increase effectiveness of preventive interventions. The combination of personalized care, prediction of treatment success, prevention of disease and patient participation in the elaboration of the treatment plan is expected to substantially improve the therapeutic approach for individuals suffering from chronic disabling conditions. Given the emerging dat…
Mutual inductance for an explicitly finite number of turns
2011
Published version of an article published in Progress In Electromagnetics Research B, 28, 273-287. Also available from the publisher at http://www.jpier.org/pierb/pier.php?paper=10110103 Non coaxial mutual inductance calculations, based on a Bessel function formulation, are presented for coils modelled by an explicitly finite number of circular turns. The mutual inductance of two such turns can be expressed as an integral of a product of three Bessel functions and an exponential factor, and it is shown that the exponential factors can be analytically summed as a simple geometric progression, or other related sums. This allows the mutual inductance of two thin solenoids to be expressed as an…
Hsp60 Involvement During Carcinogenesis
2019
The implication of Hsp60 in cancer development is due to its participation in many metabolic and biomolecular mechanisms in cancer cells. Hsp60 interacts with various molecules that are responsible of apoptosis, cell proliferation and other mechanisms involved when a normal cell becomes malignant. Hsp60 expression was found to be increased in many types of cancer but in same tumors of different anatomical district was found decreased. The mechanism of action of Hsp60 is different depending on the type of tumor. Its involvement in the carcinogenetic process of some tumors, such as large bowel carcinoma or cervical carcinoma, seems to occur in the very early stages of disease. Hsp60 participa…
The C-X-C Motif Chemokine Ligand 1 Sustains Breast Cancer Stem Cell Self-Renewal and Promotes Tumor Progression and Immune Escape Programs
2021
Breast cancer (BC) mortality is mainly due to metastatic disease, which is primarily driven by cancer stem cells (CSC). The chemokine C-X-C motif ligand-1 (CXCL1) is involved in BC metastasis, but the question of whether it regulates breast cancer stem cell (BCSC) behavior is yet to be explored. Here, we demonstrate that BCSCs express CXCR2 and produce CXCL1, which stimulates their proliferation and self-renewal, and that CXCL1 blockade inhibits both BCSC proliferation and mammosphere formation efficiency. CXCL1 amplifies its own production and remarkably induces both tumor-promoting and immunosuppressive factors, includingSPP1/OPN,ACKR3/CXCR7,TLR4,TNFSF10/TRAILandCCL18and, to a lesser exte…
EMU and the Euro-Mediterranean Dialogue: Trade Interdependence between Mediterranean and Euro-area Countries
2009
Economic interdependence and trade encourage international dialogue and represent a base for reducing international conflicts. Hence, international co-operation for the reduction of barriers to trade and capital flows can be important not only in inducing economic progress, but also in promoting peace (Polachek and Siegle 2006). In this respect, the introduction of the euro represents an epochal event for both the participants in the single European currency and for their external partners, and in particular those in neighbouring regions. However, whilst a large body of literature has focused on analysing the first, in particular, with respect to the impact of the euro on intra-regional tra…