Search results for " Plastic"

Effect of position and force tool control in friction stir welding of dissimilar aluminum-steel lap joints for automotive applications

2020

Widespread use of aluminum alloys for the fabrication of car body parts is conditional to the use of appropriate welding methods, especially if dissimilar welding must be performed with automotive steel grades. Friction stir welding (FSW) is considered to be a reasonable solution to obtain sound aluminum-steel joints. In this context, this work studies the effects of tool position and force control in dissimilar friction stir welding of AA6061 aluminum alloy on DC05 low carbon steel in lap joint configuration, also assessing proper welding parameter settings. Naked eye and scanning electron microscopy (SEM) have been used to detect macroscopic and microscopic defects in joints, as well as t…

Uncovering Technological and Environmental Potentials of Aluminum Alloy Scraps Recycling Through Friction Stir Consolidation

2020

Conventional metal chips recycling processes are energy-intensive with low efficiency and permanent material losses during re-melting. Solid state recycling allows direct recycling of metal scraps into semi-finished products. It is expected that this process category would lower the environmental performance of metals recycling. Friction Stir Consolidation is a new solid-state technique taking advantage of friction heat generation and severe plastic deformation to consolidate chips into billets. In this research, the feasibility of Friction Stir Consolidation as aluminum chips recycling process is analyzed. Specifically, an experimental campaign has been carried out with varying main proces…

Application of linear friction welding for joining ultrafine grained aluminium

2020

Abstract Ultrafine grained (UFG) materials are of great potential in industry due to their enhanced mechanical strength and other promising features, such as ability to superplastic deformation or excellent corrosion resistance. Nevertheless, one of the main limitations lies in their low thermal stability, which leads to excessive grain growth at elevated temperature. It influences mainly further processes performed at high temperature, such as joining. It causes detrimental problems during conventional fusion welding, as significant grain growth is observed and therefore the advantages as a result of small average grain size disappear. Therefore, the idea of applying solid state joining pr…

A Mechanical Approach for Evaluating the Distribution of Confinement Pressure in FRP-Wrapped Rectangular Columns

2019

In recent decades, fiber reinforced polymer (FRP) wrapping has become a common technique to retrofit reinforced concrete (RC) columns. Numerous research works have sought to verify analytically and experimentally its effectiveness in terms of enhancement of axial load bearing capacity and ductility. These studies highlighted that in the case of sharp-cornered sections, the maximum allowable confinement pressure is limited by premature failure at corners and, consequently, stress in the FRP, as well as the distribution of the confinement pressure, is not uniform. The prediction of this phenomenon is not straightforward, and existing theoretical studies propose complex numerical simulations, …

The Deep Lingual Artery Axial Propeller flap in intraoral reconstructions

2016

Editorial

"Free or Perforator-Pedicled Propeller Flaps in Lower Extremity Reconstruction: Defining the Coverage Failure": Response.

2018

Bifunctional poly(acrylamide) hydrogels through orthogonal coupling chemistries

2019

Biomaterials for cell culture allowing simple and quantitative presentation of instructive cues enable rationalization of the interplay between cells and their surrounding microenvironment. Poly(acrylamide) (PAAm) hydrogels are popular 2D-model substrates for this purpose. However, quantitative and reproducible biofunctionalization of PAAm hydrogels with multiple ligands in a trustable, controlled, and independent fashion is not trivial. Here, we describe a method for bifunctional modification of PAAm hydrogels with thiol- and amine- containing biomolecules with controlled densities in an independent, orthogonal manner. We developed copolymer networks of AAm with 9% acrylic acid and 2% N-(4…

Positive Controls in Adults and Children Support That Very Few, If Any, New Neurons Are Born in the Adult Human Hippocampus.

2020

Adult hippocampal neurogenesis was originally discovered in rodents. Subsequent studies identified the adult neural stem cells and found important links between adult neurogenesis and plasticity, behavior, and disease. However, whether new neurons are produced in the human dentate gyrus (DG) during healthy aging is still debated. We and others readily observe proliferating neural progenitors in the infant hippocampus near immature cells expressing doublecortin (DCX), but the number of such cells decreases in children and few, if any, are present in adults. Recent investigations using dual antigen retrieval find many cells stained by DCX antibodies in adult human DG. This has been interprete…

The close link between the fetal programming imprinting and neurodegeneration in adulthood: The key role of “hemogenic endothelium” programming

2021

The research on neurodegenerative diseases (NeuroDegD) has been traditionally focused on later life stages. There is now an increasing evidence, that they may be programmed during early development. Here, we propose that NeuroDegD are the result of the complex process of imprinting on fetal hemogenic endothelium, from which the microglial cells make to origin. The central role of placenta and epigenetic mechanisms (methylation of DNA, histone modifications and regulation by non-coding RNAs) in mediating the short and long-term effects has been also described. Precisely, it reports their role in impacting plasticity and memory of microglial cells. In addition, we also underline the necessity…

Heat shock protein (Hsp) regulation by muscarinic acetylcholine receptor (mAChR) activation in the rat hippocampus.

2018

The cholinergic system plays a crucial role in modulating in the central nervous system physiological responses such as neurogenesis, neuronal differentiation, synaptic plasticity, and neuroprotection. In a recent study, we showed that Oxotremorine-M, a non-selective muscarinic acetylcholine receptor agonist, is able to transactivate the fibroblast growth factor receptor and to produce a significant increase in the hippocampal primary neurite outgrowth. In the present study we aimed to explore in the rat hippocampus the possible effect of acute or chronic treatment with Oxotremorine-M on some heat shock proteins (Hsp60, Hsp70, Hsp90) and on activation of related transcription factor heat sh…