Search results for " Premature"

showing 2 items of 172 documents

OXADIAZOLE DERIVATIVES FOR THE TREATMENT OF GENETIC DISEASES DUE TO NONSENSE MUTATIONS

2018

Are disclosed oxadiazole derivatives, their use as medicaments and in particular for the treatment of diseases associated with the presence of a nonsense mutation in the gene or a premature stop codon in the mRNA, pharmaceutical formulation comprising said oxadiazole derivatives and prodrug or mixture thereof and the methods for the preparation of said Oxadiazole derivatives.

oxadiazoles read through promoters TRIDs Cystic Fibrosis genetic diseases nonsense mutations premature termination codons drugs
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Novel molecules for the readthrough of PTCs in biological model systems and in cystic fibrosis cells

2016

readthrough; premature stop codons; PTC; cystic fibrosis; novel moleculesnovel moleculesPTCreadthroughpremature stop codoncystic fibrosi
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