Search results for " Principi"

Poly lactic acid based scaffolds for vascular tissue engineering

2012

A critical obstacle encountered by tissue engineering is the inability to maintain large masses of living cells upon transfer from the in vitro culture conditions to host in vivo. Capillaries, and the vascular system, are required to supply essential nutrients, including oxygen, remove waste products and provide a biochemical communication "highway". The successful use of tissue-engineered constructs is currently limited to thin or avascular tissues, such as skin or cartilage, for which post-implantation neovascularisation from the host is sufficient to meet the demand for oxygen and nutrients. To succeed in the application of tissue engineering for bigger tissues, such as bone or muscle, t…

Pervaporation membrane reactors (Chapter 3)

2013

Experimental and computational investigation of heat transfer in channels filled by woven spacers

2017

Abstract Models of woven-type spacer-filled channels were investigated by Computational Fluid Dynamics (CFD) and parallel experiments in order to characterize the performance of Membrane Distillation (MD) modules. The case of overlapped spacers was analysed in a companion paper. Experiments were based on a non-intrusive technique using Thermochromic Liquid Crystals (TLC) and digital image processing, and provided the distribution of the local convective heat transfer coefficient on a thermally active wall. CFD simulations ranged from steady-state conditions to unsteady and early turbulent flow, covering a Reynolds number interval of great practical interest in real MD applications. A specif…

Reverse electrodialysis: Applications

2016

Reverse electrodialysis (RED) technology has grown significantly in the last decade, gaining a fast increase in its technology readiness level and presenting some interesting examples of RED pilot systems operating under very different real environments. In this chapter, an overview of technological developments and piloting examples are reported. In particular, a short introduction is given on the historical trend of RED technology growth, followed by a careful analysis of which feed solutions can be adopted and how these can affect the process performance, potentials, and applications. Most prominent fluid dynamics aspects for the RED process are presented, highlighting how these can infl…

Polyactide Biodegradable Scaffolds for Tissue Engineering Applications: Phase Separation-Based Techniques

2011

One of the most reliable techniques for the preparation of biodegradable scaffolds suitable for tissue engineering applications (e.g. regeneration of wounded/damaged tissues) is based on liquid/liquid phase separation of ternary solvent/antisolvent/polymer solutions. In particular, two phase separation protocols are examined here: Thermally Induced Phase Separation (TIPS) and Diffusion Induces Phase Separation (DIPS). According to the former protocol, a thermodynamically stable polymeric ternary solution is brought below its metastability/instability point (spinodal/binodal curve) by quench in a cooling medium: under opportune conditions, a foam-like structure is formed by nucleation and 3-…

Particle distribution in unbaffled stirred vessels

2017

The present work is devoted to providing an insight into the solid-particle distribution within top-covered unbaffled stirred tanks via purposely collected local experimental data. Experiments were carried out on a lab- scale unbaffled stirred tank by making use of a recently introduced technique named Laser Sheet Image Analysis (LSIA). In its original formulation, the technique includes an image post-processing procedure to delete reflection effects on results. In the framework of the present work, a method combining the use of purposely produced fluorescent particles and a suitable camera high pass filter was devised and presented. Results collected with (new method) and without (old fash…

On the simulation of stirred tank reactors via computational fluid dynamics

2000

Abstract Predictions of flow fields in a stirred tank reactor, obtained by computational fluid dynamics, were used for the simulation of a mixing sensitive process consisting of two parallel reactions competing for a common reagent: A + B → Prod .1 A + C → Prod .2. Experimental data were obtained for A = OH − , B = 1 2 Cu ++ and C=ethyl-chloroacetate. For this reaction scheme the final selectivity of the process, easily measured by a simple colorimetric analysis of the residual Cu++, was found to depend on agitation speed and therefore on the mixing history during the batch process. The flow field-based three-dimensional simulations performed here led to predictions that compared very well …

Performance of a RED system with ammonium hydrogen carbonate solutions

2016

The use of closed-loop salinity gradient power (SGP) technologies has been recently presented as a viable option to generate power using low-grade heat, by coupling a SGP unit with a thermally-driven regeneration process in a closed loop where artificial solutions can be adopted for the conversion of heat into power. Among these, the closed-loop reverse electrodialysis (RED) process presents a number of advantages such as the direct production of electricity, the extreme flexibility in operating conditions and the recently demonstrated large potentials for industrial scale-up. Ammonium hydrogen carbonate (NH4HCO3) is a salt suitable for such closed-loop RED process thanks to its particular …

Flow and mass transfer in spacer-filled channels for reverse electrodialysis: a CFD parametrical study

2016

Abstract In reverse electrodialysis (RED) concentration polarization phenomena and pressure drop affect strongly the power output obtainable; therefore the channel geometry has a crucial impact on the system optimization. Both overlapped and woven spacers are commonly commercialised and adopted for RED experiments; the latter exhibit some potential advantages, such as better mixing and lower shadow effect, but they have been poorly investigated in the literature so far. In this work, computational fluid dynamics was used to predict fluid flow and mass transfer in spacer-filled channels for RED applications. A parametric analysis for different spacer geometries was carried out: woven (w) and…

La rappresentanza apparente: verso un nuovo modello di rappresentanza

2022

ABSTRACT RAPPRESENTATNZA APPARENTE L’autore propone una ricostruzione della rappresentanza apparente, in grado di avallare il consolidamento di un modello uniforme di rappresentanza e di imputazione dei rapporti giuridici, fondato sull’agire per conto altrui e sul principio di affidamento. Seguendo autorevoli insegnamenti, che attribuivano all’agire nell’interesse altrui la base sostanziale dell’istituto rappresentativo, l’autore individua diverse forme di agire rappresentativo, il cui dato comune sarebbe dato dall’agire per conto altrui e dal principio di affidamento. Nonostante lo schema disegnato dall’art. 1388 c.c. descriva una fattispecie caratterizzata dalla presenza dei requisiti del…