Search results for " Program"
showing 10 items of 3075 documents
Speciation of tin(II) in aqueous solution: thermodynamic and spectroscopic study of simple and mixed hydroxocarboxylate complexes
2013
This contribution reports the results of potentiometric and Mossbauer investigations on the formation, stability, and structure of binary and ternary mono- and binuclear complexes of Sn2+ with three hydroxocarboxylic ligands (namely L = tartrate, malate, and citrate) and chloride at T = 298.15 K in different ionic media and ionic strengths (0.15 and 1.00 mol dm−3 in NaCl(aq) and 1.00 mol dm−3 in NaNO3(aq)). The stability constants of various simple Sn i H j L (2+−) and mixed Sn i H j L k Cl (2+−−) species obtained in the different experimental conditions are reported, and various speciation diagrams of the simple and mixed systems are shown in different conditions. The sequestering ability …
Ethanol-Based Post-processing of Generator-Derived 68Ga Toward Kit-Type Preparation of 68Ga-Radiopharmaceuticals
2014
Post-processing by means of a cation-exchanger–based protocol is an efficient strategy for purification and concentration of generator-derived 68Ga. It ensures the removal of 68Ge before 68Ga-radiopharmaceutical preparation and high labeling yields of 68Ga-labeled radiopharmaceuticals for routine medical application. Methods: In an effort to overcome the problem associated with acetone in the currently applied method, we have investigated the feasibility of replacing it with ethanol. The purification of 68Ga from coeluted metallic impurities (68Ge4+, Fe3+, Zn2+, and Ti4+) on various cation-exchange columns has been investigated with a variety of post-processing solutions. As a proof of prin…
The Renaissance of the 68Ge/68Ga Radionuclide Generator Initiates New Developments in 68Ga Radiopharmaceutical Chemistry
2010
⁶⁸Ge/⁶⁸Ga radionuclide generators have been investigated for almost fifty years now, since the cyclotron-independent availability of positron emitting ⁶⁸Ga via the ⁶⁸Ge/⁶⁸Ga system had always attracted researches working in basic nuclear chemistry as well as radiopharmaceutical chemistry. However, it took decades and generations of research (and researchers) to finally approach a reliable level of ⁶⁸Ge/⁶⁸Ga generator designs, adequate to the modern requirements of radiometal labeling chemistry. ⁶⁸Ga radiopharmacy now is awaking from a sort of hibernation. The exciting perspective for the ⁶⁸Ge/⁶⁸Ga generator, now - more than ever, asks for systematic chemical, radiochemical, technological an…
Improved column-based radiochemical processing of the generator produced 68Ga.
2011
An improved chemical strategy for processing of the generator produced (68)Ga was developed based on processing of the original (68)Ge/(68)Ga generator eluate on a micro-column. Direct pre-concentration and purification of the eluted (68)Ga is performed on a cation-exchange resin in hydrochloric acid/acetone media. A supplementary step based on a second micro-column filled with a second resin allows direct re-adsorption of (68)Ga eluted from the cation exchanger. (68)Ga is finally striped from the second resin with a small volume of pure water. For this purpose a strong anion exchanger and a novel extraction chromatographic resin based on tetraalkyldiglycolamides are characterized. The stra…
Maturation of a Key Resource – The Germanium-68/Gallium-68 Generator: Development and New Insights
2011
(68)Ge/(68)Ga radionuclide generators have been investigated for almost fifty years, since the cyclotron-independent availability of positron emitting (68)Ga via the (68)Ge/(68)Ga system had always attracted researches working in basic nuclear chemistry as well as radiopharmaceutical chemistry. However, it took decades and generations of research (and researchers) to finally reach a level of (68)Ge/(68)Ga radionuclide generator designs adequate to the modern requirements of radiometal labelling chemistry. Nevertheless, most of the existing commercial generator systems address aspects of (68)Ge breakthrough and safe synthesis of (68)Ga radiopharmaceuticals by adopting eluate post-processing …
From needs to competencies : a case study on the integration of a rights based approach into NGO practises
2010
The objective of this qualitative case study is to provide knowledge on the possibilities of incorporating a rights based approach (RBA) into practises of non-governmental organisations (NGOs) in the context of development and children. The study is confined to examine the possibilities of RBA in realising children’s rights within the child sponsorship programme (CSP) of a Finnish NGO, Fida International (Fida), and the conceptualisation of the child in regard to different approaches. The theoretical framework is built on contemporary development discourse concerning the approximation of human rights and development as well as the underlying reasons for the emergence of RBA as a contributio…
Valnerina Bike Sharing: prospettive di trasformazione territoriale
2018
Il contributo proposto intende esporre il progetto Valnerina Bike Sharing, un servizio intercomunale di bike sharing elettrico a pedalata assistita finanziato all’interno del Programma di Sviluppo Rurale per l'Umbria 2014 – 2020, che s’inserisce in un territorio compreso tra la Cascata delle Marmore e la ex ferrovia Spoleto-Norcia. Con l’obiettivo primario di incrementare il turismo responsabile in territori a elevato valore naturalistico, l'intervento intende incentivare la mobilità ciclo-pedonale, sostenibile e accessibile, utilizzando in gran misura l’arteria sentieristica della rete regionale che si snoda lungo l’asse del fiume Nera contribuendo alla definizione di un sistema unitario i…
Cittadinanza e sua commodificazione: cittadinanza come diritto, cittadinanza come bene
2019
cittadinanza e sua commodificazione
On the trail of local welfare innovations in rural Finland
2019
Final Draft In Finland, the rural areas have been most affected by the developments threatening the survival of the welfare state as well as by conflicting efforts to save it. However, there are rural communities that have—as a response to the mainstream policy emphasizing economic efficiency and individual responsibility—developed innovative solutions to secure their welfare. Based on a case study focusing on two of such communities, these local welfare innovations are a result from a combination of external causes and local resources including the sense of community and a diverse enough community structure. The authors argue that in the context of welfare policy, the promotion of local we…
Literāra darba autorības koncepts: kontekstuālie aspekti
2014
ANOTĀCIJA Balstoties uz autorības izpratni, kas autorību skaidro kā autora tiesības tikt atzītam par darba autoru - fizisko personu, kuras radošās darbības rezultātā radīts literārais darbs, Ineses Paklones promocijas darbā Literāra darba autorības koncepts: kontekstuālie aspekti kritiski izvērtēts literāra darba, autorības, autora un līdzautoru jēdzienu saturs saistībā ar to atpoguļojumu Latvijas Republikas Autortiesību likumā, tā interpretācijās no juristu viedokļa, lietojumu latviešu valodā un literatūras zinātnē. Iezīmēts autorības iegūšanas process un autorības fiksācija ar savu vārdu vai pseidonīmu, kā arī autorības zaudēšana, gan apzināti atsakoties no autorības, - darbu publicējot a…