Search results for " Promoter"
showing 10 items of 50 documents
Polar Wax as Adhesion Promoter in Polymeric Blend Films for Durable Photovoltaic Encapsulants
2022
Technological developments in the solar photovoltaic field must guarantee the high performance and low deterioration of solar cells in order for solar power plants to be more efficient and competitive. The solar cell needs comprehensive protection offered by a polymeric encapsulant, which improves UV stability, reduces water and moisture absorption, reduces oxygen and vapor permeability and enhances mechanical resistance. Moreover, high transparency and adhesion yields improved the solar panel performance. The current work analyzes polymeric films based on poly(ethylene-co-vinyl acetate) (EVA) and polyolefin (PO) for photovoltaic encapsulant use (the high temperature resistance is improved …
The HMGA1 protoncogene frequently deregulated in cancer is a transcriptional target of E2F1
2011
Reactivation of the HMGA1 protoncogene is very frequent in human cancer, but still very little is known on the molecular mechanisms leading to this event. Prompted by the finding of putative E2F binding sites in the human HMGA1 promoter and by the frequent deregulation of the RB/E2F1 pathway in human carcinogenesis, we investigated whether E2F1 might contribute to the regulation of HMGA1 gene expression. Here we report that E2F1 induces HMGA1 by interacting with a 193bp region of the HMGA1 promoter containing an E2F binding site surrounded by three putative Sp1 binding sites. Both gain and loss of function experiments indicate that Sp1 functionally interacts with E2F1 to promote HMGA1 expre…
Sea urchin neural alpha 2 tubulin gene: isolation and promoter analysis
2004
Abstract Expression of Tα2 gene, during sea urchin Paracentrotus lividus development, is spatially and temporally regulated. In order to characterize this gene, we isolated the relevant genomic sequences and scanned the isolated 5 ′ -flanking region in searching for cis -regulatory elements required for proper expression. Gel mobility shift and footprinting assays, as well as reporter gene (CAT and β-gal) expression assays, were used to address cis -regulatory elements involved in regulation. Here we report that an upstream 5 ′ -flanking fragment of PlTα2 gene drives temporal expression of reporter genes congruent with that of endogenous Tα2 gene. The fragment contains cis -elements able to…
INTER-ORGANIZATIONAL INNOVATION PROMOTERS IN SMALL, KNOWLEDGE-INTENSIVE FIRMS
2009
This paper examines the relationship between external relations and innovation in small, knowledge-intensive Norwegian firms. Our findings indicate that external relations are beneficial for innovation. The analysis shows that it is necessary to treat innovation as more than a concept. Our independent variables related differently to product innovation, process innovation, and market innovation.We found that market participation in product development has a positive impact on product, process and market innovation. We also found that top management interaction with other firms had a positive effect on market innovation and that top management interaction with external R&D had a positive…
Biologically active organic compounds, especially plant promoters, in algae extracts and their potential application in plant cultivation
2015
Scientific efforts taken during the past decades undoubtedly have proven that algae are organisms wealthy in various chemical substances such as carbohydrates, proteins, and minerals, as well as polysaccharides, polyphenols, phlorotannins, pigments, unsaturated fats, sterols, and of course growth promoting substances like phytohormones. It is noteworthy that among the many biologically active compounds obtained from seaweeds, plant hormones seem to be the most essential for enhancing the growth and development of crop plants. This fact is well reflected in over 60 years of the long history of controlled application of algae origin products as natural fertilizers in crop production. Neverthe…
Adapting Net Promoter thinking in public sector organizations
2016
Tässä maisterintutkielmassa tarkasteltiin Net Promoter score (NPS) -suosittelumittarin sopivuutta julkissektorin käyttöön. Tutkielman tavoitteena oli selvittää, sopiiko yksityisellä sektorilla paljon käytetty mittari julkissektorin organisaatioihin. Tutkimus täyttää aukon tutkimuskentällä, jossa NPS:ää on tutkittu paljon yksityisen sektorin organisaatioissa, mutta tutkimusta julkissektorilta ei tiettävästi ole tehty. Tutkimuskysymykset olivat: 1) Millaisia piirteitä julkissektorin suosittelijoilla on; 2) millaisia piirteitä julkissektorin herjaajilla on; 3) millaisia piirteitä julkissektorin passiiveilla on. Teoreettinen viitekehys käsittelee julkissektorin maine- ja tyytyväisyysmittareita …
Biologically active compounds in algae and their application in plant growth stimulation
2016
In recent years the bioactive substances of natural origin gained more and more interest. Among such substances, the compounds isolated from microalgae and seaweeds, mainly the polyphenols, polysaccharides, plant hormones, pigments and fatty acids, an find an application in many industries, particularly in medicine, pharmaceutics, cosmetics and agriculture. Biostimulants from seaweeds have been used and manufactured for years, giving confirmation of its effectiveness in field trials, enhancing the growth of crops giving better yields. Nowadays, the legislation processes are more difficult and intricate, so it is harder to register new products. Everyone put more attention on the answers for…
Alternative UNC13D Promoter Encodes a Functional Munc13-4 Isoform Predominantly Expressed in Lymphocytes and Platelets
2020
Autosomal recessive mutations in genes required for cytotoxicity are causative of a life-threatening, early-onset hyperinflammatory syndrome termed familial hemophagocytic lymphohistiocytosis (FHL). Mutations in UNC13D cause FHL type 3. UNC13D encodes Munc13-4, a member of the Unc13 protein family which control SNARE complex formation and vesicle fusion. We have previously identified FHL3-associated mutations in the first intron of UNC13D which control transcription from an alternative transcriptional start site. Using isoform specific antibodies, we demonstrate that this alternative Munc13-4 isoform with a unique N-terminus is preferentially expressed in human lymphocytes and platelets, as…
Variants of the
2019
The Gram-positive soil bacterium Bacillus subtilis relies on the glutamine synthetase and the glutamate synthase for glutamate biosynthesis from ammonium and 2-oxoglutarate. During growth with the carbon source glucose, the LysR-type transcriptional regulator GltC activates the expression of the gltAB glutamate synthase genes. With excess of intracellular glutamate, the gltAB genes are not transcribed because the glutamate-degrading glutamate dehydrogenases (GDHs) inhibit GltC. Previous in vitro studies revealed that 2-oxoglutarate and glutamate stimulate the activator and repressor function, respectively, of GltC. Here, we have isolated GltC variants with enhanced activator or repressor fu…
OXADIAZOLE DERIVATIVES FOR THE TREATMENT OF GENETIC DISEASES DUE TO NONSENSE MUTATIONS
2018
Are disclosed oxadiazole derivatives, their use as medicaments and in particular for the treatment of diseases associated with the presence of a nonsense mutation in the gene or a premature stop codon in the mRNA, pharmaceutical formulation comprising said oxadiazole derivatives and prodrug or mixture thereof and the methods for the preparation of said Oxadiazole derivatives.