Search results for " REM"

showing 10 items of 1460 documents

Airway remodelling assessed by sputum and high resolution computed tomography in asthma and COPD

2004

It is not known whether sputum elastase, metalloproteinase (MMP)-9 and tissue-inhibitor metalloproteinase (TIMP)-1 are related to structural changes of the airways, as assessed by high-resolution computed tomography (HRCT) scan. The relationships between these markers and the magnitude of structural changes of the airways in asthma and chronic obstructive pulmonary disease (COPD) were assessed. Induced sputum and HRCT scan were performed in 30 asthmatics (14 mild and 16 severe) and in 12 patients with COPD. A greater extent of HRCT scan abnormalities was found in COPD than in severe and mild asthmatics. HRCT scan abnormalities correlated with the degree of airway obstruction in COPD and in …

AdultMalePulmonary and Respiratory Medicinemedicine.medical_specialtyPathologyHigh-resolution computed tomographyairway inflammation imagingSettore MED/10 - Malattie Dell'Apparato RespiratorioGastroenterologyStatistics NonparametricPulmonary Disease Chronic ObstructiveInternal medicinemedicineHumansAirway RemodellingAgedAsthmaCOPDTissue Inhibitor of Metalloproteinase-1Pancreatic Elastasemedicine.diagnostic_testbusiness.industryElastaseRespiratory diseaseSputumMiddle Agedrespiratory systemAirway obstructionmedicine.diseaseAsthmaRespiratory Function Testsrespiratory tract diseasesMatrix Metalloproteinase 9SputumFemalemedicine.symptomTomography X-Ray Computedbusiness
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Rate of Cataract Formation in 343 Highly Myopic Eyes After Implantation of Three Types of Phakic Intraocular Lenses

2004

ABSTRACT PURPOSE: To assess the feasibility of using phakic intraocular lenses (PIOL) to treat high myopia, and evaluate the incidence of cataract, comparing three different lens types. METHODS: From 1989 to 2002, we implanted three different phakic intraocular lenses (PIOL) in 343 eyes of 232 patients; 231 eyes recieved an Ophtec (Worst-Fechner model, iris-claw), 89 an Adatomed (silicone posterior chamber), and 23 a Staar (posterior chamber, models V2, V3, V4). Average follow-up was 96.2 months for the Ophtec group, 31.5 months for the Adatomed group, and 19.3 months for Staar group. Eyes that subsequently developed cataract were studied for clinical evolution and had PIOL explantation and…

AdultMaleRefractive errormedicine.medical_specialtyAnterior subcapsular cataractVisual acuitygenetic structuresEye diseasemedicine.medical_treatmentVisual AcuityIntraocular lensPhakic intraocular lensCataractlaw.inventionLens Implantation IntraocularlawOphthalmologyMyopiamedicineHumansDevice RemovalAgedLenses Intraocularbusiness.industryIncidencePhacoemulsificationMiddle Agedmedicine.diseaseeye diseasesLens (optics)OphthalmologyFeasibility StudiesFemaleSurgerysense organsmedicine.symptombusinessJournal of Refractive Surgery
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Complex radial head and neck fractures treated with modern locking plate fixation

2019

Background Internal fixation of complex radial head and neck (CRHN) fractures is difficult, and postoperative complications are common. This study evaluated elbow function and patient clinical status after internal fixation of CRHN fractures with modern locking plates. Methods We included 40 patients with 41 fractures (1 bilateral lesion). In 25 patients (61%), a concomitant injury was found. Patients were an average age of 46 years (range, 22-70 years). The mean follow-up time was 36 months (range, 2-70 months). Postoperative assessments included evaluation of range of motion, functional scores, and radiologic findings. We assessed fracture healing, surgical complications, revision surgery…

AdultMaleReoperationmedicine.medical_specialtyJoint replacementmedicine.medical_treatmentElbowBone healingSupinationFracture Fixation InternalYoung Adult03 medical and health sciencesFixation (surgical)0302 clinical medicineElbow JointHumansMedicineInternal fixationPronationOrthopedics and Sports MedicineRange of Motion ArticularDevice RemovalAgedFracture Healing030222 orthopedicsbusiness.industry030229 sport sciencesGeneral MedicineMiddle AgedSurgeryTreatment Outcomemedicine.anatomical_structureConcomitantFemaleSurgeryRadial head fractureRadius FracturesbusinessRange of motionBone PlatesEpiphysesFollow-Up StudiesJournal of Shoulder and Elbow Surgery
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Criteria for defining a complete remission in acute myeloid leukaemia revisited. An analysis of patients treated in HOVON-SAKK co-operative group stu…

2005

Complete remission (CR) in patients with acute myeloid leukaemia (AML) is the primary endpoint for the evaluation of induction treatment and treatment strategies. However, the choice and application of the criteria for a haematological CR can often become a subject of debate because of regeneration more than 5% blasts may be present at the time of response evaluation; platelet and neutrophil recovery may be incomplete and marrow cellularity can vary. This study examined the individual parameters for CR in 1250 adult patients with de novo AML treated according to three successive study protocols. Patients with < or =5% blasts showed the best overall survival (OS) and the lowest relapse risk …

AdultMaleRiskmedicine.medical_specialtyPathologyAdolescentcomplete remissionMINIMAL RESIDUAL DISEASEDIAGNOSISGastroenterologyTHERAPYDisease-Free SurvivalAMLRecurrencehemic and lymphatic diseasesInternal medicineAntineoplastic Combined Chemotherapy ProtocolsmedicineClinical endpointHumansPlateletacute myeloid leukaemiaLymphocyte CountProportional Hazards ModelsrevisedHematologycriteriaProportional hazards modelbusiness.industryINDUCTIONRemission InductionCancerHematologyMiddle AgedCOLONY-STIMULATING FACTORmedicine.diseaseMinimal residual diseaseCANCERHIGH-DOSE CYTARABINELeukemiamedicine.anatomical_structureLeukemia MyeloidAcute DiseaseFemaleBone marrowbusinessBritish Journal of Haematology
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Long-term bony integration and resorption kinetics of a xenogeneic bone substitute after sinus floor augmentation: histomorphometric analyses of huma…

2013

In this case series, a systematic histomorphometric analysis of two human bone biopsy specimens was conducted 1 and 5 years after grafting with a xenogeneic bovine bone substitute material (BSM). While the 1-year specimen still showed extensive signs of an active desmal ossification, the specimen after 5 years mainly showed mature lamellar bone without bone turnover or remodeling. A completed bony integration without extensive resorption of the BSM particles could be detected. Altogether, a good integration in the bone with osteoconduction and a high biocompatibility was seen.

AdultMaleSinus Floor AugmentationBone RegenerationBone substituteBiopsyHuman boneDentistryBone MatrixSinus Floor AugmentationOsteocytesBone remodelingImaging Three-DimensionalOsseointegrationOsteogenesisBiopsymedicineMaxillaAnimalsHumansLongitudinal StudiesBone ResorptionMineralsBone Transplantationmedicine.diagnostic_testOssificationbusiness.industryDental Implantation EndosseousMembranes ArtificialX-Ray MicrotomographyMiddle AgedResorptionBovine boneBone SubstitutesPeriodonticsHeterograftsCattleFemaleCollagenOral Surgerymedicine.symptombusinessFollow-Up Studies
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REM-associated hallucinations and sleep paralysis are dependent on body posture

2001

AdultMaleSleep Wake Disordersmedicine.medical_specialtyNeurologyHallucinationsPostureSleep REMSleep ParalysisPhysical medicine and rehabilitationHumansMedicineAgedNarcolepsyNeuroradiologybusiness.industryBody postureMiddle Agedmedicine.diseaseSleep in non-human animalsNeurologyFemaleNeurology (clinical)businessSleep paralysisNarcolepsyJournal of Neurology
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Adaptation to life after surgical removal of the bladder—an application of graphical Markov models for analysing longitudinal data

2004

Graphical Markov models have been developed particularly for the analysis of observational data. They allow the control of various background variables when analysing theoretically relevant associations. This paper demonstrates the application and some advantages of graphical Markov models in comparison to conventional statistical analyses. The aim of the study was to identify patients at risk for developing decreased health-related quality of life (QoL) after cystectomy and to explore the influence of coping on QoL in this situation. Therefore, the method was applied to analyse the data of a prospective study, in which 81 patients with bladder cancer were interviewed pre-operatively and in…

AdultMaleStatistics and ProbabilityLongitudinal studyCoping (psychology)Operations researchEpidemiologyLongitudinal datamedicine.medical_treatmentMarkov modelCystectomySurgical removalAdaptation PsychologicalmedicineHumansLongitudinal StudiesProspective cohort studyMiddle AgedMarkov ChainshumanitiesUrinary Bladder NeoplasmsResearch DesignQuality of LifeFemaleObservational studyPsychologyClinical psychologyStatistics in Medicine
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The planimetric Grothoff's criteria by cardiac magnetic resonance can improve the specificity of left ventricular non-compaction diagnosis in thalass…

2020

We differentiated the left ventricle non-compaction (LVNC) from hypertrabeculated myocardium due to a negative remodeling in thalassemia intermedia (TI) patients applying linear and planimetric criteria and comparing the cardiovascular magnetic resonance (CMR) findings. CMR images were analyzed in 181 TI patients enrolled in the Myocardial Iron Overload in Thalassemia Network and 27 patients with proved LVNC diagnosis. The CMR diagnostic criteria applied in TI patients were: a modified linear CMR Petersen’s criterion based on a more restrictive ratio of diastolic NC/C &gt; 2.5 at segmental level and the combination of planimetric Grothoff’s criteria (percentage of trabeculated LV myocardial…

AdultMaleThalassemia intermedia · Magnetic resonance imaging · Isolated non-compaction of the ventricular myocardium · ventricular remodelingmedicine.medical_specialtyDatabases FactualThalassemiaIronDiastoleMagnetic Resonance Imaging CineVentricular Function LeftDiagnosis DifferentialYoung AdultPredictive Value of TestsInternal medicinemedicineHumansRadiology Nuclear Medicine and imagingVentricular remodelingCardiac imagingObserver VariationIsolated Noncompaction of the Ventricular Myocardiummedicine.diagnostic_testVentricular Remodelingbusiness.industryMyocardiumbeta-ThalassemiaReproducibility of ResultsMagnetic resonance imagingMiddle Agedmedicine.diseaseFibrosismedicine.anatomical_structureVentricleCase-Control StudiesCardiologyFemaleThalassemia intermediaCardiology and Cardiovascular MedicinebusinessCardiac magnetic resonanceCardiomyopathiesBiomarkers
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Online detection of rem sleep based on the comprehensive evaluation of short adjacent eeg segments by artificial neural networks

1997

Abstract 1. 1. For scientific and clinical requirements the present objective is a robust automatic online algorithm to detect rapid eye movement (REM) steep from single channel sleep EEG data without using EMG or EOG information. 2. 2. For data preprocessing 20 seconds time periods of the continuous EEG activity are digitally filtered in 7 frequency bands. Then the RMS values of these filtered signals are calculated along segments of 2.5 seconds. The resulting matrix of RMS values is representing information on the power of the signal localized in time and frequency and serves as input to an artificial neural network. A pooled set of EEG data together with the corresponding manual evaluati…

AdultMaleTime FactorsChannel (digital image)Sleep REMWord error rateElectroencephalographyOnline SystemsSignalmedicineHumansWakefulnessOnline algorithmBiological PsychiatryPharmacologymedicine.diagnostic_testArtificial neural networkbusiness.industryReproducibility of ResultsEye movementElectroencephalographyPattern recognitionNeural Networks ComputerSleep StagesData pre-processingArtificial intelligencePsychologybusinessAlgorithmsProgress in Neuro-Psychopharmacology and Biological Psychiatry
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Dynamical properties of the sleep EEG in different frequency bands.

1993

The information concerning the dynamic behavior of the sleep process gained by the usual evaluation of sleep EEGs according to the criteria of Rechtschaffen and Kales is limited. Therefore a new methodical approach is presented, which is a special case of spectral analyzed data processing. After digital band-pass filtering of the sleep EEG the root-mean-square (RMS) value of successive 20 s EEG epochs is calculated in defined frequency ranges. This procedure ensures to take into account the influence of the phase relation between different frequency components. The temporal course of these RMS values during the night reveals smooth curves with continuous transitions between different sleep …

AdultMaleTime FactorsFrequency bandmedia_common.quotation_subjectSleep REMElectroencephalographyRadio spectrumRoot mean squaremedicineHumansStatistical physicsWakefulnessmedia_commonCommunicationQuantitative Biology::Neurons and Cognitionmedicine.diagnostic_testbusiness.industryGeneral NeuroscienceObservableElectroencephalographyGeneral MedicineMaxima and minimaSleep StagesPsychologybusinessSleepDigital filterVigilance (psychology)The International journal of neuroscience
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