6533b85dfe1ef96bd12bdf78

RESEARCH PRODUCT

Long-term bony integration and resorption kinetics of a xenogeneic bone substitute after sinus floor augmentation: histomorphometric analyses of human biopsy specimens.

Hermann GötzMarcus O. KleinWilfried WagnerHeinz DuschnerPeer W. Kämmerer

subject

AdultMaleSinus Floor AugmentationBone RegenerationBone substituteBiopsyHuman boneDentistryBone MatrixSinus Floor AugmentationOsteocytesBone remodelingImaging Three-DimensionalOsseointegrationOsteogenesisBiopsymedicineMaxillaAnimalsHumansLongitudinal StudiesBone ResorptionMineralsBone Transplantationmedicine.diagnostic_testOssificationbusiness.industryDental Implantation EndosseousMembranes ArtificialX-Ray MicrotomographyMiddle AgedResorptionBovine boneBone SubstitutesPeriodonticsHeterograftsCattleFemaleCollagenOral Surgerymedicine.symptombusinessFollow-Up Studies

description

In this case series, a systematic histomorphometric analysis of two human bone biopsy specimens was conducted 1 and 5 years after grafting with a xenogeneic bovine bone substitute material (BSM). While the 1-year specimen still showed extensive signs of an active desmal ossification, the specimen after 5 years mainly showed mature lamellar bone without bone turnover or remodeling. A completed bony integration without extensive resorption of the BSM particles could be detected. Altogether, a good integration in the bone with osteoconduction and a high biocompatibility was seen.

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