Search results for " Reading"

A New Branch-and-Cut Algorithm for the Generalized Directed Rural Postman Problem

2016

The generalized directed rural postman problem, also known as the close-enough arc routing problem, is an arc routing problem with some interesting real-life applications, such as routing for meter reading. In this article we introduce two new formulations for this problem as well as various families of new valid inequalities that are used to design and implement a branch-and-cut algorithm. The computational results obtained on test bed instances from the literature show that this algorithm outperforms the existing exact methods

Digital Technologies for the Fruition of Archaeological Heritage. The Visualisation of the Temple C Metopes Polychrome in Selinunte

2019

Through the tools of the representation this paper investigates a hypothetical virtual re-presentation of the metopes original polychromies. The reconstructive interpretative process was carried out through a critical reading of historical and iconographic sources. Starting from the reading of drawings made by Angell and Harris at the time of the archaeological finds, of Hittorff’s studies and watercolors, and of some coloured fragments still observable in the original metopes, the graphic elaborations that simulate the original polychromes have been prepared. The purpose of this study and of the analysis here described is the experimentation of an interactive visualisation application (aug…

Genomic structure and functional characterization of the human ADAM10 promoter

2005

The ADAM10 gene encodes a membrane-bound disintegrin-metalloproteinase, which, after overexpression in an Alzheimer disease (AD) mouse model, prevents amyloid pathology and improves long-term potentiation and memory. Because enhancing ADAM10 expression appears to be a reasonable approach for treatment of AD, we functionally analyzed the ADAM10 gene. Both human and mouse ADAM10 genes comprise approximately 160 kbp, are composed of 16 exons, and are evolutionarily highly conserved within 500 bp upstream of either translation initiation site. By using luciferase reporter assays, we demonstrate that nucleotides -2179 to -1 upstream of the human ADAM10 translation initiation site represent a fun…

Literacy programs efficacy for developing children’s early reading skills in familiar language in Zambia

2018

This study investigated the comparative efficacy of a phonics-based reading program and a language experience approach based literacy program to develop reading skills among Zambian early childhood school learners. The learners (n = 1 986; Grade 2 level; females = 50.1%) took either the phonics-based reading program (n = 1 593) or the alternative language experience approach based program (n = 393). They were all assessed for reading skills utilising the Early Grade Reading Assessment test (EGRA) in four languages (Cinyanja, Icibemba, Kiikaonde, and Silozi). Results suggest that learners in phonics-based literacy program were significantly better in letter-sound knowledge in all the four la…

Formulations and exact algorithms for the distance-constrained generalized directed rural postman problem

2017

[EN] The generalized directed rural postman problem is an arc routing problem with many interesting real-life applications, such as routing for meter reading. In this application, a vehicle with a receiver travels through a series of neighborhoods. If the vehicle gets closer than a certain distance to a meter, the receiver is able to record the gas, water, or electricity consumption. Therefore, the vehicle does not need to traverse every street, but only a few, to get close enough to each meter. We study an extension of this problem in which a fleet of vehicles is available. Given the characteristics of the mentioned application, the vehicles have no capacities but there is a maximum distan…

Lectura y procesamiento de información

1983

An improvement of ComiR algorithm for microRNA target prediction by exploiting coding region sequences of mRNAs

2020

AbstractMicroRNA are small non-coding RNAs that post-transcriptionally regulate the expression levels of messenger RNAs. MicroRNA regulation activity depends on the recognition of binding sites located on mRNA molecules. ComiR is a web tool realized to predict the targets of a set of microRNAs, starting from their expression profile. ComiR was trained with the information regarding binding sites in the 3’utr region, by using a reliable dataset containing the targets of endogenously expressed microRNA in D. melanogaster S2 cells. This dataset was obtained by comparing the results from two different experimental approaches, i.e., inhibition, and immunoprecipitation of the AGO1 protein--a comp…

Genetic organization of the citCDEF locus and identification of mae and clyR genes from Leuconostoc mesenteroides.

1999

ABSTRACT In this paper, we describe two open reading frames coding for a NAD-dependent malic enzyme ( mae ) and a putative regulatory protein ( clyR ) found in the upstream region of citCDEFG of Leuconostoc mesenteroides subsp. cremoris 195. The transcriptional analysis of the citrate lyase locus revealed one polycistronic mRNA covering the mae and citCDEF genes. This transcript was detected only on RNA prepared from cells grown in the presence of citrate. Primer extension experiments suggest that clyR and the citrate lyase operon are expressed from a bidirectional A-T-rich promoter region located between mae and clyR.

Educación compensatoria : aprendizaje temprano, éxito posterior : (II: el Carolina Abecedarian Project)

2014

Este es un estudio de revisión en el que se analizan las investigaciones que evalúan los efectos a lo largo del tiempo del programa de educacióntemprano Abecedarian Project (ABC). El ABC es un programa compensador preventivo de 0-5 años y entresacados de madres de alto riesgo. El grupo experimental (E) recibe tratamiento preescolar intensivo, no el control (C). Se prolongó escolarmente hasta los 8 años, subdividiéndose ambos grupos: Dos -EE y CE- recibieron tratamiento intensivo; otros (EC y CC) convencional. Fueron medidos hasta los 21. Resultados: Los jóvenes adultos, tratados preescolarmente, mejoraron en rendimiento mental, lector y matemático; alcanzaron mayores instrucciones y presenc…

The Affective Geography of Paris in the 19th Century Romanian Novel: Between Admiration and Aversion

2020

Based on “The Emotions of London”, a research project initiated at the Stanford Literary Lab, my article focuses on two relevant issues. First of all, I aim to demonstrate, as the “geography of emotions” experiment has already proved, that distant reading approaches and big data interpretation do not necessarily have to replace traditional methods of analysis. In other words, by using a corpus of 157 texts, I intend to outline the affective image of Paris as presented in the nineteenth century Romanian novel. Secondly, the aspect that makes my article different from “The Emotions of London” is that my purpose does not lie in analysing emotions associated with certain place-names in Paris, b…