Search results for " Real-time PCR."

showing 4 items of 14 documents

Studies on the response of soil microflora to the application of the fungicide fenhexamid

2007

The aim of this work was to evaluate the impact of the fungicide fenhexamid (FEX) on the genetic structure of soil bacterial communities using the Ribosomal Intergenic Spacer Analysis molecular technique. Using real-time PCR, we also tried to quantify the pcaH sequences which encode the dioxygenases involved in the degradation process of a variety of aromatic compounds. Soil taken from a vineyard in the Etna Park (Sicily, Italy) was treated with FEX in the ratio 2 µg g-1 soil every 7 days, the process being repeated four times. The analyses were carried out before treatment and 7 days after each further application of FEX. At the same time, the degradation rate was evaluated. The use of FEX…

Soil microfloraEcology[SDV]Life Sciences [q-bio]Health Toxicology and MutagenesisRibosomal Intergenic Spacer analysisRIBOSOMAL INTERGENIC SPACER ANALYSISFenhexamidPublic Health Environmental and Occupational HealthSoil ScienceMolecular TechniqueBiologyPollutionVineyardAnalytical ChemistryFungicideHorticultureRISA[SDE]Environmental SciencesReal-time PCR RISAEnvironmental ChemistryREAL-TIME PCRDegradation processWaste Management and DisposalFenhexamid; Real-time PCR RISA; Soil microfloraWater Science and TechnologyInternational Journal of Environmental Analytical Chemistry
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Transcription of human neuronal nitric oxide synthase mRNAs derived from different first exons is partly controlled by exon 1-specific promoter seque…

2006

AbstractThe human neuronal nitric oxide synthase (NOS1) gene is subject to extensive splicing. A total of 12 NOS1 mRNA species have been identified. They differ in their 5′ ends and are derived from 12 different first exons (termed exons 1a to 1l). Various cell lines whose NOS1 first exon expression patterns were representative of human brain, skin, and skeletal muscle were identified. These included A673 neuroepithelioma cells, SK-N-MC neuroblastoma cells, HaCaT keratinocyte-like cells, and C2C12 myocyte-like cells. In these cell lines, correlations were found between the exon 1 variants preferentially expressed and the promoter activities of their cognate 5′ flanking sequences. These data…

Transcription Genetic5' Flanking Region5' flanking regionReporter gene assaysSkeletal muscleNitric Oxide Synthase Type IBiologyKidneyHippocampusCell LineRT real-time PCRExonExon trappingGenes ReporterTestisGeneticsHumansRNA MessengerCloning MolecularLuciferasesPromoter Regions GeneticGeneSkinBinding SitesSplice site mutationReverse Transcriptase Polymerase Chain ReactionAlternative splicingGenetic VariationHeartExonsMolecular biologyAlternative SplicingRNA splicingCortexTandem exon duplicationProtein BindingTranscription FactorsGenomics
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Role of nitric oxide synthase (NOS) of Klebsormidium nitens: Identification and characterization of partners

2021

National audience; Nitric oxide (NO) is an important cellular signaling molecule across kingdoms. During bioticor abiotic stresses, NO burst is detected in both plants and mammals although no sequenceencoding the well described mammalian NO synthase (NOS) is highlighted in plants. Comparedto terrestrial plants, some algae present transcripts encoding the NOS-like enzyme. Amongthem, Klebsormidium nitens the model alga to study the early transition step from aquatic algaeto land plants is found. As mechanisms governing NO synthesis and signaling in green lineageremain unclear, the study of NOS from K. nitens (KnNOS) through (i) the identification ofregulator proteins, (ii) the identification …

algae[SDV] Life Sciences [q-bio]abiotic stressnitric oxide synthase[SDV]Life Sciences [q-bio]reference genequantitative real-time PCRNOS algae
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Differential expression of two glucocorticoid receptors in seabass (teleost fish) head kidney after exogeneous cortisol inoculation

2009

Stressful conditions include a prompt release of corticosteroid hormones which can mediate gene expression through glucocorticoid receptors (GR). Since two seabass (Dicentrarchus labrax) GRs have been cloned and sequenced from peritoneal cavity cells (DlGR1) and liver (DlGR2), a comparative amino acid sequence analysis that included Haplochromis burtoni HbGRs, was carried out and homologies disclosed. The DlGR1 and DlGR2 deduced aminoacid sequences showed 61% identity (I) and 70% similarity (S). Moreover, DlGR2 was similar to HbGR2b (69% I, 73% S), and the DlGR1 to HbGR1 (72% I, 78% S). In addition, we examined the expression of the DlGRs after exogeneous cortisol inoculation into the perit…

medicine.medical_specialtyHydrocortisonePhysiologySettore BIO/05 - ZoologiaGlucocorticoid receptorKidneyBiochemistryCortisolPeritoneal cavityGlucocorticoid receptorReceptors GlucocorticoidInternal medicineGene expressionmedicineAnimalsDicentrarchus labraxSea bassMolecular BiologyDicentrarchus labrax; Cortisol; Glucocorticoid receptor; Real-time PCRHead KidneyKidneybiologyReverse Transcriptase Polymerase Chain ReactionGene Expression Profilingbiology.organism_classificationmedicine.anatomical_structureEndocrinologyGene Expression RegulationHormone receptorDicentrarchusBassReal-time PCR
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