Search results for " Regression Analysis"

showing 10 items of 82 documents

Clinical and biochemical determinants of the extent of liver steatosis in type 2 diabetes mellitus

2015

Objective Nonalcoholic fatty liver disease is very frequent in both type 2 diabetes mellitus (T2DM) and the metabolic syndrome (MS), which share clinical and metabolic characteristics. Whether and to which extent these characteristics can predict the degree of liver steatosis are not entirely clear. Patients and methods We determined liver fat (divided into four classes) by standard sonographic images, and clinical and biochemical variables, in 60 consecutive patients with T2DM and with features of the MS. We examined both simple and multiple correlations between the degree of liver steatosis and the variables measured. Results Increased liver fat (defined as >5% of liver mass) was detec…

Malenonalcoholic fatty liver diseasemedicine.medical_specialtytype 2 diabetes mellitusmedicine.medical_treatmentSettore MED/50 - Scienze Tecniche Mediche ApplicateGastroenterologyleptinliver steatosispredictive modelInsulin resistanceNon-alcoholic Fatty Liver DiseaseInternal medicineinsulin resistanceNonalcoholic fatty liver diseasemedicineHumansInsulinAdiposityAgedUltrasonographyvisceral adiposityGlycated HemoglobinMetabolic SyndromeSettore SECS-S/06 - Metodi mat. dell'economia e Scienze Attuariali e FinanziarieModels StatisticalAnthropometryHepatologybusiness.industryInsulinHemoglobin A1c; insulin resistance; leptin; liver steatosis; metabolic control; multiple regression analysis; nonalcoholic fatty liver disease; predictive model; type 2 diabetes mellitus; visceral adiposity;GastroenterologyType 2 Diabetes MellitusHemoglobin A1c; insulin resistance; leptin; liver steatosis; metabolic control; multiple regression analysis; nonalcoholic fatty liver disease; predictive model; type 2 diabetes mellitus; visceral adiposity; Gastroenterology; Hepatologymetabolic controlmultiple regression analysisMiddle AgedHepatologymedicine.diseaseEndocrinologyDiabetes Mellitus Type 2Hemoglobin A1cMetabolic control analysisFemaleWaist CircumferenceSteatosisMetabolic syndromebusinesshemoglobin A1c leptin liver steatosis metabolic control multiple regression analysis nonalcoholic fatty liver disease insulin resistance predictive model type 2 diabetes mellitus visceral adiposity
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Physical Activity Trends of Finnish Adolescents With Long-Term Illnesses or Disabilities From 2002–2014

2016

Background:Adolescents’ physical activity level is a major source of concern. For adolescents with long-term illnesses or disabilities (LTID), being physically active can prevent secondary conditions. This is one of the first studies reporting trends in physical activity of adolescents with LTID in relation to gender, age, and sports club membership.Methods:Data were collected from the Health Behavior in School-aged Children study in Finland during 2002, 2006, 2010, and 2014. In 13- and 15-year-olds (N = 2206), 17.1% reported having LTID. Daily physical activity recall was the dependent variable. Binary logistic regression analysis was conducted eparately for sports club members (n = 936) a…

Maleorganized sportsmedicine.medical_specialtyAdolescentmedia_common.quotation_subjectHealth BehaviorPhysical activity030209 endocrinology & metabolismHistory 21st Century03 medical and health sciences0302 clinical medicineHumansMedicineOrthopedics and Sports MedicineBinary logistic regression analysis030212 general & internal medicineGirlExercisephysical activity recommendationsFinlandmedia_commonbusiness.industryPhysical activity levelPhysical therapyFemaleHealth Behavior in School-aged Children StudyClubHealth behaviorbusinessDemographyJournal of Physical Activity and Health
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Three decades of subsidiary exits: Parent firm financial performance and moderators

2020

Abstract This study aimed to find important constructs and relationships among models of subsidiary divestment during the period from 1989 to 2018 using correlation matrices of 80 studies, the selection of which was based on six criteria. It revealed eight important constructs, namely firm innovativeness, environmental factors in the target country, type of experience, organizational characteristics, investment strategy, parent firm financial performance, subsidiary divestment, and the moderating effects of advertising intensity and product diversification. Furthermore, it shed light on seven relationships that should be considered in future attempts to assess parent performance related to …

MarketingFinancial performanceInvestment strategy05 social sciencesDiversification (marketing strategy)ModerationMultinomial logistic regression analysisNegocis0502 economics and business050211 marketingBusiness050203 business & managementDivestmentIndustrial organizationJournal of Business Research
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A time series study on the effects of heat on mortality and evaluation of heterogeneity into European and Eastern-Southern Mediterranean cities: resu…

2013

Background: The Mediterranean region is particularly vulnerable to the effect of summer temperature. Within the CIRCE project this time-series study aims to quantify for the first time the effect of summer temperature in Eastern-Southern Mediterranean cities and compared it with European cities around the Mediterranean basin, evaluating city characteristics that explain between-city heterogeneity. Methods: The city-specific effect of maximum apparent temperature (Tappmax) was assessed by Generalized Estimation Equations, assuming a linear threshold model. Then, city-specific estimates were included in a random effect meta-regression analysis to investigate the effect modification by several…

Mediterranean climateMaleMESH: Urban HealthHot TemperatureTime FactorsClimateHealth Toxicology and MutagenesisVulnerability010501 environmental sciences01 natural sciencesMediterranean BasinMESH: Regression AnalysisMESH: Cause of Death0302 clinical medicineAfrica NorthernMESH: ChildCause of Death11. Sustainability030212 general & internal medicineMediterranean regionSocioeconomicsChildMESH: Aged[SDV.EE]Life Sciences [q-bio]/Ecology environmentMiddle EastMESH: Middle AgedMESH: Infant Newborn1. No povertyAge FactorsMiddle AgedMESH: ClimateMESH: Middle East/epidemiologyMESH: Infant3. Good healthGeographyMESH: Young AdultChild Preschool8. Economic growthRegression AnalysisFemaleSeasonsAdultmedicine.medical_specialtyAdolescentClimate changeHeat Stress DisordersMESH: Mediterranean Region/epidemiology03 medical and health sciencesMiddle EastYoung AdultmedicineMESH: CitiesHumansCitiesMortalityMESH: Heat Stress Disorders/mortality*0105 earth and related environmental sciencesMESH: Hot Temperature/adverse effectsAgedEstimationMESH: AdolescentMESH: Age FactorsMESH: Heat Stress Disorders/etiologyMESH: HumansPublic healthResearchMESH: Child PreschoolMESH: Time FactorsInfant NewbornUrban HealthPublic Health Environmental and Occupational HealthMESH: Africa Northern/epidemiologyInfantMESH: AdultMESH: MaleApparent temperature13. Climate actionHot temperature; Mortality; Mediterranean region; Heterogeneity; Age groups; Public Health; TIME series analysis; Older people; Public health; Unemployment statistics; Climatic changes[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologieMESH: Mortality/trends*HeterogeneityAge groupsMESH: FemaleMESH: SeasonsMedicine; Geriatrics
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Intraosseous monitoring of drilling in lumbar vertebrae by ultrasound: An experimental feasibility study.

2016

The rationale for this project is to evaluate the efficiency of a novel sonographic method for measurements of interosseous distances. The method utilizes a propagating ultrasonic beam through aqueous milieu which is directed as a jet into a drilled tract. We used a plastic model of human L5 vertebra and ex vivo specimen of L5 porcine vertebra and generated 2 mm in diameter tracts in vertebral pedicles. The tracts were created in the "desired" central direction and in the "wrong" medial and lateral directions. The drilled tracts and the residual, up to opposite cortex, distances were measured sonographically and mechanically and compared statistically. We show that "true" mechanical measure…

Models AnatomicVertebraeSwinelcsh:MedicineReflectionDistance Measurement01 natural sciences0302 clinical medicineMathematical and Statistical TechniquesBone DensityMedicine and Health SciencesOrthopedic Procedureslcsh:Science010301 acousticsMusculoskeletal SystemMeasurementMultidisciplinaryUltrasonic beamLumbar VertebraePhysicsUltrasoundClassical MechanicsAnatomymedicine.anatomical_structureConnective TissuePhysical SciencesEngineering and TechnologyRegression AnalysisTomographyAnatomyPlasticsGeologyStatistics (Mathematics)Research Articlemusculoskeletal diseasesMaterials ScienceMaterial PropertiesSurgical and Invasive Medical ProceduresLumbar vertebraeLinear Regression AnalysisResearch and Analysis Methods03 medical and health sciencesLumbar0103 physical sciencesmedicineAnimalsHumansL5 VertebraStatistical MethodsBoneUltrasonography Interventionalbusiness.industrylcsh:RDrillingBiology and Life SciencesSpineVertebraBiological TissueSignal ProcessingLinear ModelsFeasibility Studieslcsh:QbusinessTomography X-Ray Computed030217 neurology & neurosurgeryMathematicsPloS one
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DesMol2, an Effective Tool for the Construction of Molecular Libraries and Its Application to QSAR Using Molecular Topology

2019

A web application, DesMol2, which offers two main functionalities, is presented: the construction of molecular libraries and the calculation of topological indices. These functionalities are explained through a practical example of research of active molecules to the formylpeptide receptor (FPR), a receptor associated with chronic inflammation in systemic amyloidosis and Alzheimer&rsquo

Models MolecularMultilinear mapQuantitative structure–activity relationshiplinear discriminant analysisComputer scienceQuantitative Structure-Activity RelationshipPharmaceutical ScienceComputational biology01 natural sciencesArticleAnalytical ChemistrySmall Molecule Librarieslcsh:QD241-44103 medical and health scienceslcsh:Organic chemistryDrug DiscoveryPhysical and Theoretical ChemistryPiperazineDesMol2030304 developmental biology0303 health sciencesMolecular Structure010405 organic chemistryOrganic Chemistrymolecular librariesBase (topology)Linear discriminant analysisReceptors Formyl PeptideSystemic amyloidosis0104 chemical sciencestopology descriptorsmultilinear regression analysisDiscriminantChemistry (miscellaneous)Molecular MedicineMultiple linear regression analysisMolecular topologyAlzheimer’s diseaseDatabases ChemicalSoftwareProtein BindingMolecules
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Application of molecular topology to the prediction of the antimalarial activity of a group of uracil-based acyclic and deoxyuridine compounds.

2008

A topological-mathematical model has been arranged to search for new derivatives of deoxyuridine and related compounds acting as antimalarials against Plasmodium falciparum. By using linear discriminant and multilinear regression analysis a model with two functions was capable to predict adequately the IC(50) for each compound of the training and test series. After carrying out a virtual screening based upon such a model, new structures potentially active against P. falciparum are proposed.

Models MolecularStereochemistryChemistry PharmaceuticalPlasmodium falciparumPharmaceutical ScienceQuantitative Structure-Activity Relationshipchemistry.chemical_compoundAntimalarialsUser-Computer Interfaceparasitic diseasesAnimalsTechnology PharmaceuticalComputer SimulationUracilTopology (chemistry)Virtual screeningbiologyMolecular StructureDiscriminant AnalysisUracilPlasmodium falciparumLinear discriminant analysisbiology.organism_classificationDeoxyuridineDeoxyuridinechemistryDrug DesignComputer-Aided DesignRegression AnalysisMultiple linear regression analysisMolecular topologyInternational journal of pharmaceutics
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Hemostatic agents in endodontic surgery of maxillary molars : a randomized controlled pilot study of polytetrafluoroethylene (PTFE) strips as an adju…

2019

Background Hemostasis is of critical importance in endodontic surgery. Studies on bleeding control in maxillary molars are scarce. The present study compares the efficacy of two hemostatic techniques in controlling bleeding in endodontic surgery. Material and Methods A randomized two-arm pilot study involving 30 patients with peri-radicular lesions in maxillary molars (first and second molars) was carried out including the following hemostatic agents: polytetrafluoroethylene (PTFE) strips as an adjunct to epinephrine impregnated gauze (test group; n = 15) and aluminum chloride (Expasyl™) (control; n = 15). Bleeding control was independently assessed by the surgeon and by two blinded observe…

MolarEpinephrineDentistryPilot ProjectsHemostaticsMandibular second molar03 medical and health scienceschemistry.chemical_compound0302 clinical medicinemedicineAluminum ChlorideHumansBinary logistic regression analysisGeneral DentistryPolytetrafluoroethyleneHemostatic AgentPolytetrafluoroethylenebusiness.industryHemostatic TechniquesResearch030206 dentistry:CIENCIAS MÉDICAS [UNESCO]MolarEndodontic surgeryEpinephrineOtorhinolaryngologychemistryHemostasisUNESCO::CIENCIAS MÉDICASSurgeryOral Surgerybusinessmedicine.drug
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Structural invariants for the prediction of relative toxicities of polychloro dibenzo-p-dioxins and dibenzofurans

2004

Multivariate models are reported that can predict the relative toxicity of compounds with severe environmental impact, namely polychloro dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs). Multiple linear regression analysis (MLR) and partial least square projections of latent variables (PLS) show the usefulness of graph-theoretical descriptors, mainly topological charge indices (TCIs), in these series. The general trends of the group are correctly reproduced and better results are presented than have previously been published. In general, the more toxic compounds exhibit more symmetric molecular structures.

Multivariate statisticsCarcinoma HepatocellularPolychlorinated DibenzodioxinsRelative toxicityQuantitative Structure-Activity RelationshipLatent variableDioxinsCatalysisInorganic ChemistryToxicologyComputational chemistryDrug DiscoveryLinear regressionCytochrome P-450 CYP1A1AnimalsSoil PollutantsLeast-Squares AnalysisPhysical and Theoretical ChemistryMolecular BiologyBenzofuransModels StatisticalChemistryOrganic ChemistryReproducibility of Resultsfood and beveragesNeoplasms ExperimentalGeneral MedicineModels TheoreticalRatsDisease Models AnimalModels ChemicalDrug DesignMultivariate AnalysisLinear ModelsEnvironmental PollutantsMultiple linear regression analysisInformation SystemsMolecular Diversity
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Multivariate regression analysis applied to the calibration of equipment used in pig meat classification in Romania.

2016

This paper highlights the statistical methodology used in a dissection experiment carried out in Romania to calibrate and standardize two classification devices, OptiGrade PRO (OGP) and Fat-o-Meat'er (FOM). One hundred forty-five carcasses were measured using the two probes and dissected according to the European reference method. To derive prediction formulas for each device, multiple linear regression analysis was performed on the relationship between the reference lean meat percentage and the back fat and muscle thicknesses, using the ordinary least squares technique. The root mean squared error of prediction calculated using the leave-one-out cross validation met European Commission (EC…

Multivariate statisticsMeatMean squared errorFood HandlingSwine0211 other engineering and technologies02 engineering and technologyCross-validationStatisticsCalibrationMedicineAnimals021110 strategic defence & security studiesbusiness.industryBack fatRomania0402 animal and dairy scienceRegression analysis04 agricultural and veterinary sciences040201 dairy & animal scienceAdipose TissueOrdinary least squaresCalibrationBody CompositionMultiple linear regression analysisbusinessFood ScienceMeat science
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