Search results for " Regulation"
showing 10 items of 3187 documents
Activation of TRK Genes in Ewingʼs Sarcoma Trk A Receptor Expression Linked to Neural Differentiation
1997
Trk receptors have been identified by immunohistochemical methods in primitive neuroectodermal tumor (PNET)/Ewing's sarcoma (ES). However, the presence of different members of the Trk family of receptors in PNET/ES has not been specified. We have examined whether Trk A, B, and C receptors are specifically expressed in ES both with and without features of neural differentiation. Ten ES tumors (five primary tumors of bone and five extraosseous tumors transplanted into nude mice) were investigated for expression of Trk receptors by immunohistochemistry and reverse transcription-polymerase chain reaction. One primary ES and the five grafted ES tumors exhibited signs of neural differentiation; t…
Production of cecropin A in transgenic rice plants has an impact on host gene expression.
2008
Summary Expression of the cecropin A gene in rice confers resistance to the rice blast fungus Magnaporthe oryzae. In this study, a polymerase chain reaction-based suppression subtractive hybridization approach was used to generate a cDNA macroarray from the elite japonica rice (Oryza sativa L.) cultivar ‘Senia’. Gene expression studies revealed that the expression of components of the protein secretory and vesicular transport machinery is co-ordinately activated at the pre-invasive stage of infection of rice by the blast fungus. Comparisons of gene expression between wild-type and cecropin A plants revealed the over-expression of genes involved in protection against oxidative stress in tran…
Differential genomic imprinting regulates paracrine and autocrine roles of IGF2 in mouse adult neurogenesis
2015
Genomic imprinting is implicated in the control of gene dosage in neurogenic niches. Here we address the importance of Igf2 imprinting for murine adult neurogenesis in the subventricular zone (SVZ) and in the subgranular zone (SGZ) of the hippocampus in vivo. In the SVZ, paracrine IGF2 is a cerebrospinal fluid and endothelial-derived neurogenic factor requiring biallelic expression, with mutants having reduced activation of the stem cell pool and impaired olfactory bulb neurogenesis. In contrast, Igf2 is imprinted in the hippocampus acting as an autocrine factor expressed in neural stem cells (NSCs) solely from the paternal allele. Conditional mutagenesis of Igf2 in blood vessels confirms t…
Nucleotide sequence of an adult-specific cuticular protein gene from the beetle Tenebrio molitor: effects of 20-hydroxyecdysone on mRNA accumulation.
1993
0962-1075 (Print) Journal Article Research Support, Non-U.S. Gov't; The accumulation of transcripts from two adult-specific cuticular genes (ACP-20 and ACP-22) is shown to be modified after addition of exogenous 20-hydroxyecdysone. In the continuous presence of high levels of the hormone, the expression of ACP-20 gene is significantly weaker than that of untreated controls, while ACP-22 expression is 2.5-fold increased. During active synthesis of the ACP messages, a 0.5 microg 20-hydroxyecdysone injection causes a rapid 2-fold increase in ACP-22 mRNA and is not able to repress ACP-20 mRNA accumulation. We conclude that these genes whose transcripts appear in an almost coordinated manner in …
Apzinātība, emociju regulācija un pašefektivitāte Iespējamās Misijas un citu augstāko izglītību pedagoģijā ieguvušiem skolotājiem.
2016
Pētījuma mērķis bija noskaidrot, vai pastāv atšķirības starp Iespējamās Misijas skolotāju un Latvijas Universitātes topošo skolotāju apzinātības, pašefektivitātes un emociju regulācijas rādītājiem, kā arī, kādas saistības pastāv starp šiem trim mainīgajiem. Datu ievākšanai tika izmantotas 3 aptaujas: Emociju regulācijas aptauja (Emotion Regulation Questionnaire /ERQ/, Gross & John, 2003). Latvijā instrumenta sākotnējā adaptācija tika veikta maģistra darba ietvaros (Morozova, 2011); Norvēģu skolotāju pašefektivitātes skala (Norwegian Teacher Self-Efficacy Scale jeb NTSES (Skaalvik & Skaalvik, 2007)). Latviešu valodā sākotnējā versija adaptēta kursa darba ietvaros (Virse, 2015); Apzinātības p…
Psicobiologia dell'attaccamento
2008
In this work, the emotional and cerebral development of the individual is treated as a complex process, within which genetic and experiential factors interact; equal focus is given to these factors as is through the interactions of both that the human brain achieves full maturity. The recent literature on neuroscientific findings has allowed to understand further which are the mechanisms that play the most important role in the human brain. In particular, this recent work has pointed out the importance of precocious experiences of emotional syntonization between the baby and its development partners; the quality of the experiences that such partners will be able to provide will configure no…
L'attività normativa del governo nel periodo 2017-2019
2022
L’articolo descrive l’attività normativa del governo nel periodo 2017-2019. Per quanto riguarda le procedure di programmazione e revisione della spesa pubblica, le riforme del 2016 finalizzate alla riduzione della spesa dei Ministeri hanno trovato applicazione solo nel 2017, mentre nel 2018 e nel 2019 ulteriori risparmi sono stati conseguiti mediante apposite previsioni delle leggi di bilancio. Le principali innovazioni in materia di liberalizzazione sono state portate a termine nel 2017, mentre non vi sono stati interventi rilevanti nel biennio successivo. Per quanto concerne il decentramento di funzioni amministrative, non si sono riscontrati progressi. Le politiche di privatizzazione son…
Nuevas perspectivas de la política y del derecho audiovisual
1999
Cuando constatamos, en tiempos de presente y futuro, la realidad y perspectivas del sector audiovisual en el marco de la UE podemos advertir la importancia e influencia de este sector en la construcción europea. Basta, para ello, apelar a tres tipos de razones: el gran auge y crecimiento que está experimentando este sector, tanto en inversión como en creación de empleos, en estos momentos y que todavía será mayor en el siglo XXI -con todo lo que implica en el aumento del peso específico de este sector en el conjunto de la economía comunitaria-; la gran transformación que está experimentando este sector con el tránsito de la tecnología analógica hacia la tecnología digital y que va a suponer…
The increase in maternal expression of axin1 and axin2 contribute to the zebrafish mutant ichabod ventralized phenotype.
2014
β-Catenin is a central effector of the Wnt pathway and one of the players in Ca(+)-dependent cell-cell adhesion. While many wnts are present and expressed in vertebrates, only one β-catenin exists in the majority of the organisms. One intriguing exception is zebrafish that carries two genes for β-catenin. The maternal recessive mutation ichabod presents very low levels of β-catenin2 that in turn affects dorsal axis formation, suggesting that β-catenin1 is incapable to compensate for β-catenin2 loss and raising the question of whether these two β-catenins may have differential roles during early axis specification. Here we identify a specific antibody that can discriminate selectively for β-…
Banche e mercato del credito in Italia: tendenze di mercato, prospettive regolamentari e processi di disintermediazione.
2020
Il capitolo vuole fornire alcuni spunti di riflessione sulle tendenze del mercato del credito in Italia e sulle nuove prospettive regolamentari, in relazione alle innovazioni di carattere istituzionale e di mercato in atto nel sistema bancario italiano, adottando una prospettiva di osservazione che è quella dell’economia della banca. Nella prima parte saranno illustrate le dinamiche che hanno contrassegnato il mercato del credito italiano, nonché i principali profili gestionali relativi ai crediti deteriorati. Nella seconda parte saranno esaminati gli impatti sul mercato del credito delle nuove regole di vigilanza prudenziale, delle nuove regole contabili e sul capitale delle banche, i proc…