Search results for " Repair"

showing 10 items of 721 documents

Tunica vaginalis Free Grafts for Closure of Urethrocutaneous Fistulas

1990

In 32 patients a tunica vaginalis free graft was used for closure of urethrocutaneous fistulas (n = 26) or complicated hypospadias repair (n = 6). All patients had at least one operation (average 3.9) for urethral reconstruction prior to this procedure. 12 patients had recurrent fistulas (average 2.2). The technique proved to be very successful. Only 2 patients had to undergo subsequent reoperation for recurrent fistulas. The use of a free tunica vaginalis graft interposed between skin and urethra is our method of choice in the repair of recurrent or complicated urethrocutaneous fistulas.

AdultMalemedicine.medical_specialtyPenile DiseasesAdolescentUrinary FistulaUrologyEpispadiasPostoperative ComplicationsTestisUrethral DiseasesMethodsHypospadias repairHumansMedicineChildHypospadiasbusiness.industryFree graftTunica vaginalisTunica vaginalis testismedicine.diseaseSurgerymedicine.anatomical_structureUrethraHypospadiasChild PreschoolbusinessUrologia Internationalis
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Partial versus complete removal of the infected mesh after abdominal wall hernia repair.

2017

Background: To compare the results with complete mesh removal (CMR) versus partial mesh removal (PMR) in the treatment of mesh infection after abdominal wall hernia repair (AWHR). Methods: Retrospective review of all patients who underwent surgery for mesh infection between January 2004 and May 2014 at a tertiary center. Results: Of 3470 cases of AWHR, we reported 66 cases (1.9%) of mesh infection, and 48 repairs (72.7%) required mesh explantation. CMR was achieved on 38 occasions, while PMR was undertaken ten times. We observed more postoperative complications in CMR than PMR group (p = 0.04). Three patients with intestinal fistula were reoperated in postoperative period after a difficult …

AdultMalemedicine.medical_specialtyProsthesis-Related InfectionsFistulamedicine.medical_treatment030230 surgeryMesh explantationAbdominal wall03 medical and health sciences0302 clinical medicinePostoperative ComplicationsRecurrencemedicineHumansDevice RemovalProsthetic infectionAgedRetrospective StudiesRetrospective reviewbusiness.industryAbdominal WallMesh infectionGeneral MedicineLength of StayMiddle AgedSurgical Meshmedicine.diseaseHernia repairHernia VentralSurgerymedicine.anatomical_structure030220 oncology & carcinogenesisAbdominal wall herniaHernia repairSurgeryFemalebusinessAmerican journal of surgery
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Predictors of mesh infection and explantation after abdominal wall hernia repair

2015

Abstract Background The main objective was to identify predictive factors associated with prosthesis infection and mesh explantation after abdominal wall hernia repair (AWHR). Methods This is a retrospective review of all patients who underwent AWHR from January 2004 to May 2014 at a tertiary center. Multivariate analysis identified predictors of mesh infection and explantation after AWHR. Results From 3,470 cases of AWHR, we reported 66 cases (1.9%) of mesh infection, and 48 repairs (72.7%) required mesh explantation. Steroid or immunosuppressive drugs use (odds ratio [OR] 2.22; confidence interval [CI] 1.16 to 3.95), urgent repair (OR 5.06; CI 2.21 to 8.60), and postoperative surgical sit…

AdultMalemedicine.medical_specialtyProsthesis-Related Infectionsmedicine.medical_treatment030230 surgeryEnterotomyProsthesisAbdominal wall03 medical and health sciences0302 clinical medicineRisk FactorsmedicineHumansSurgical Wound InfectionProsthesis-Related InfectionDevice RemovalHerniorrhaphyAgedRetrospective Studiesbusiness.industryIncidenceAbdominal WallRetrospective cohort studyGeneral MedicineOdds ratioMiddle AgedSurgical MeshHernia repairHernia VentralSurgerySurgical meshmedicine.anatomical_structure030220 oncology & carcinogenesisFemaleSurgerybusinessThe American Journal of Surgery
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Clinical and Functional Outcome After Abdominal Wall Incisional Hernia Repair: Evaluation of Quality-of-Life Improvement and Comparison of Assessment…

2019

Background Hernias severely impact patient quality of life (QoL), and 80% of patients need surgical operation. The primary outcome of the study is to assess improvements in balance, posture and deambulation after abdominal hernia repair. Moreover, the study investigated the improvement in the postoperative QoL. Methods Patients operated at the Policlinico “Paolo Giaccone” at Palermo University Hospital between June 2015 and June 2017 were identified in a prospective database. The functional outcome measures and QoL assessment scales used were numeric rating scale for pain, performance-oriented mobility assessment (POMA) scale, Quebec back pain disability scale, center of gravity (barycenter…

AdultMalemedicine.medical_specialtyPsychometricsAbdominal Hernia030230 surgeryAbdominal wall03 medical and health sciences0302 clinical medicineQuality of lifeBack painNumeric Rating ScaleMedicineHumansIncisional HerniaHerniaPostoperative PeriodProspective StudiesProspective cohort studyHerniorrhaphyAgedPain Measurementbusiness.industryAbdominal WallQuebecAbdominal wall incisional hernia repair Qol posture barycenter deambulationRecovery of FunctionMiddle AgedSurgical Meshmedicine.diseaseHealth SurveysHernia Ventralmedicine.anatomical_structureTreatment Outcome030220 oncology & carcinogenesisPhysical therapyQuality of LifeSurgeryFemalemedicine.symptombusinessAbdominal surgeryWorld journal of surgery
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Descriptive and follow-up study of patients treated surgically for abdominal aortic aneurysm at tertiary hospitals in Spain.

2019

BACKGROUND The aim of this study was to assess potential variability in the clinical characteristics and treatment of patients undergoing elective surgery for abdominal aortic aneurysm (AAA) across five hospitals in Spain. METHODS Multicenter, retrospective cohort study of patients diagnosed with AAA and treated with open surgical repair (OSR) or endovascular aneurysm repair (EVAR). We evaluated clinical and demographic variables, including comorbidity (Charlson Comorbidity Index [CCI]); anatomic characteristics; surgical risk (ASA Score); aneurysm characteristics; and in-hospital and overall mortality. All patients were followed for three years. RESULTS A total of 186 patients were include…

AdultMalemedicine.medical_specialtyTime Factorsmedicine.medical_treatment030204 cardiovascular system & hematology030230 surgeryEndovascular aneurysm repairTertiary Care Centers03 medical and health sciencesBlood Vessel Prosthesis Implantation0302 clinical medicineAneurysmPostoperative ComplicationsRisk FactorsmedicineHumansHospital MortalityRisk factorElective surgeryPractice Patterns Physicians'AgedRetrospective StudiesAged 80 and overbusiness.industryMortality ratePatient SelectionEndovascular ProceduresRetrospective cohort studyOdds ratioMiddle Agedmedicine.diseaseAbdominal aortic aneurysmSurgeryLogistic ModelsTreatment OutcomeElective Surgical ProceduresSpainMultivariate AnalysisFemaleCardiology and Cardiovascular MedicinebusinessAortic Aneurysm AbdominalFollow-Up StudiesInternational angiology : a journal of the International Union of Angiology
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Multiple periscope and chimney grafts to treat ruptured thoracoabdominal and pararenal aortic aneurysms

2011

Purpose: To report midterm outcomes after urgent endovascular repair of ruptured pararenal or thoracoabdominal aortic aneurysms using multiple periscope and chimney grafts to preserve renovisceral branch perfusion and facilitate aneurysm exclusion. Methods: Nine consecutive men (mean age 72614 years, range 40–88) presenting with ruptured thoracoabdominal (n56), pararenal (n52), or infrarenal (n51) aortic aneurysm underwent urgent endovascular repair with at least 1 periscope graft delivered via a transfemoral access; chimney grafts were installed from an axillary access. In all, 17 periscope and 7 chimney grafts were used to reperfuse 11 renal and 13 visceral arteries in the 9 patients. The…

AdultMalemedicine.medical_specialtyTime Factorsmedicine.medical_treatmentAortic RuptureLess invasive610 Medicine & healthRuptured Aortic AneurysmProsthesis DesignEndovascular aneurysm repairSettore MED/22 - Chirurgia VascolareAortography2705 Cardiology and Cardiovascular Medicinelaw.inventionBlood Vessel Prosthesis ImplantationlawmedicineHumans2741 Radiology Nuclear Medicine and ImagingRadiology Nuclear Medicine and imagingChimneyAgedRetrospective Studiesendodebranching renovisceral arteries chimney graft periscope graft stentgraft endograft ruptured aortic aneurysm ruptured thoracoabdominal aortic aneurysm ruptured pararenal aortic aneurysm ruptured AAA endovascular aneurysm repairAged 80 and overAortic Aneurysm Thoracicbusiness.industry10042 Clinic for Diagnostic and Interventional RadiologyEndovascular ProceduresChimney graftBlood flowMiddle AgedSurgeryBlood Vessel Prosthesis10020 Clinic for Cardiac Surgery2746 SurgeryTreatment Outcomecardiovascular systemSurgeryFemaleStentsRadiologyPeriscopeCardiology and Cardiovascular MedicinebusinessTomography X-Ray ComputedAortic Aneurysm Abdominal
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Tension-free hernia repair is associated with an increase in inflammatory response markers against the mesh.

2000

Abstract Background: The purpose of this study was to evaluate the involvement of inflammatory mediators in patients undergoing Lichtenstein tension-free hernioplasty (LH) using polypropylene prosthetic materials or conventional Bassini hernia repair (BH). Methods: Thirty patients male with unilateral inguinal hernia without complications or recurrence were included in this study. Randomly, patients underwent LH or BH. Peripheral venous bloods samples were collected 24 hours prior to surgery and then 6, 24, 48 and 168 hours postoperatively. Results: We present evidences that LH patients showed a higher increased serum level of fibrinogen, C-reactive protein, alpha-1-antitrypsin, and interle…

AdultMalemedicine.medical_treatmentInflammationHernia InguinalFibrinogenPolypropylenesProsthesis ImplantationLeukocyte CountPostoperative ComplicationsMedicineHumansHerniaPostoperative PeriodInflammationbiologybusiness.industryInterleukin-6Foreign-Body ReactionAlbuminFibrinogenGeneral MedicineMiddle AgedSurgical Meshmedicine.diseaseHernia repairPeripheralmedicine.anatomical_structureC-Reactive ProteinAnesthesiaalpha 1-Antitrypsinbiology.proteinAbdomenSurgerymedicine.symptombusinessCeruloplasminmedicine.drugAmerican journal of surgery
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Repair of the mandibular nerve by means of autologous nerve grafting after resection of the lower jaw

1973

Summary On the basis of two cases we demonstrate our method of autologous nerve grafting for substitution of the mandibular nerve after mandibular resection. The sural nerve served as a donor nerve, the graft was imbedded microsurgically at the juncture points by means of a perineurial interfascicular nerve suture. Oversized grafts of about 20 cm in length were chosen intentionally in order to insert them without tension between the stumps of the recipient nerve and outside the regeneration zone of the bone. In both cases complete resensibilization of the lower lip was reached after about six months.

AdultMicrosurgerymedicine.medical_specialtyMandibular NerveMandibular nerveLower lipSural nerveTransplantation AutologousResectionAmeloblastomaPostoperative ComplicationsSural Nervestomatognathic systemmedicineHumansParesthesiaChildNerve graftingbusiness.industryGeneral MedicineAnatomyDenervationMandibular resectionLipNerve RegenerationOsteotomySurgeryMandibular Neoplasmssurgical procedures operativeFemaleSurgeryEpineurial repairNerve suturebusinessJournal of Maxillofacial Surgery
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Activity and safety of temozolomide in advanced adrenocortical carcinoma patients

2019

Objective Temozolomide has shown a significant anti-proliferative activity on adrenocortical cancer (ACC) cells in vitro. Design On the basis of these results the drug was prescribed as second/third line in advanced metastatic ACC patients in four referral centers in Italy. Methods We retrospectively collected anagraphic, clinical and pathological data of patients with advanced ACC with disease progression to standard chemotherapy plus mitotane who were treated with temozolomide at the dose of 200 mg/m2/die given for 5 consecutive days every 28 days. The primary endpoint was the disease control rate, defined as objective response or disease stabilization after 3 months. Secondary endpoints…

AdultOncologymedicine.medical_specialtytemozolomide adrenocortical carcinomaDisease ResponseSettore MED/06 - Oncologia MedicaEndocrinology Diabetes and Metabolismmedicine.medical_treatment030209 endocrinology & metabolism03 medical and health sciences0302 clinical medicineEndocrinologyStable DiseaseInternal medicineAdrenocortical CarcinomaTemozolomideClinical endpointHumansMedicineAdrenocortical carcinomaMitotaneDNA Modification MethylasesAgedRetrospective StudiesChemotherapyTemozolomidebusiness.industryTumor Suppressor ProteinsRetrospective cohort studyGeneral MedicineMiddle Agedmedicine.diseaseDNA Repair EnzymesEndocrinology030220 oncology & carcinogenesisbusinessmedicine.drug
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Modifications in the production of cytokines and growth factors in drainage fluids following mesh implantation after incisional hernia repair

2005

Abstract Background The aim of this study was to evaluate changes in the production of some cytokines (interleukins [ILs]-6, -10, -1, and -1ra), vascular endothelial growth factor, and beta-fibroblast growth factor after polypropylene mesh implantation. Methods Twenty female patients were divided into 2 groups. In 1 group, hernia repair was performed with conventional sutures (CR), whereas in the other group polypropylene mesh (MR) was used. Growth factors and cytokines production was analyzed in wound drain fluids based on the amount produced during 24 hours. Results IL-1 increased substantially in MR patients on postoperative days 1 and 2. IL1-ra and IL-10 production was always significan…

AdultVascular Endothelial Growth Factor Amedicine.medical_specialtyincisional herniaIncisional herniamedicine.medical_treatmentEnzyme-Linked Immunosorbent AssayPolypropyleneschemistry.chemical_compoundmedicineHumansHerniaProspective StudiesPostoperative CareLaparotomyPain Postoperativebusiness.industryInterleukinsGrowth factorSuture Techniquesgrowth factorGeneral MedicineMiddle AgedSurgical Meshmedicine.diseaseHernia repairHernia Ventralinterieukinmesh implantationSurgeryVascular endothelial growth factorTreatment OutcomeCytokineSurgical meshchemistryCytokinesFemaleSurgeryInflammation MediatorsVascular endothelial growth factor productionbusinessFollow-Up Studies
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