Search results for " SUBSTRATE"

Analysis of thin film cracking and buckling on compliant substrate by fragmentation test

2007

Application of coating fragmentation test for determination of coating properties is considered. A probabilistic model of coating fragmentation under uniaxial tensile loading is applied for coating and interface property identification of thin brittle coating/polymer substrate system. A finite element model is developed to simulate the process of buckle formation in coating strips during fragmentation test. The measured buckle geometry parameters and buckle density evolution as a function of the applied strain is used to estimate the interface toughness.

2014

Pupil dilation under constant illumination is a physiological marker where modulation is related to several cognitive functions involved in daily decision making. There is evidence for a role of pupil dilation change during decision-making tasks associated with uncertainty, reward-prediction errors and surprise. However, while some work suggests that pupil dilation is mainly modulated by reward predictions, others point out that this marker is related to uncertainty signaling and surprise. Supporting the latter hypothesis, the neural substrate of this marker is related to noradrenaline (NA) activity which has been also related to uncertainty signaling. In this work we aimed to test whether …

Studi preliminari sulla propagazione gamica e vegetativa di Hypericum perforatum in ambiente mediterraneo

2014

La conoscenza dei fattori che influenzano la propagazione di una specie rappresenta un passo cruciale nella messa a punto di strategie per la sua moltiplicazione di massa e introduzione in coltura, sia in campo che in ambiente controllato. Sono stati approfonditi alcuni aspetti della propagazione gamica di Hypericum perforatum (di cui è nota la bassa germinabilità del seme), verificando in particolare gli effetti di variabili diverse (soddisfacimento delle esigenze in freddo, temperatura, substrato, presenza di PGPR, batteri promotori della crescita). Sono stati inoltre approfonditi gli studi sulle potenzialità di moltiplicazione vegetativa della specie, da proporre come possibile alternati…

Propagation of Artemisia Arborescens L. by stem-cutting: Adventitious root formation under different conditions

2012

Artemisia arborescens L. has gained a strong importance worldwide due to its many industrial uses and it has been recently considered as ornamental plant. A major constraint to its widespread cultivation is represented, by far, by the scarce availability of high-quality plant material for field establishment; hence, development of a fast and effective methods for its vegetative propagation is needed. An experiment was conducted to assess the effects of different harvest periods, NAA, and rooting substrates on rooting of stem cuttings of A. arborescens. Semi hardwood cuttings were collected from wild plants in February, April, and November. Half of the material was treated with 0.4% NAA and …

Substrat jako fundament konwencjonalizacji wtórnej sielanki staropolskiej

2022

Artykuł pt. Substrat jako fundament konwencjonalizacji wtórnej staropolskiej sielanki jest analizą najważniejszej zasady tworzącej konwencję tego gatunku, a mianowicie reguły dwupłaszczyznowości kompozycyjnej. Autorka na przykładach utworów takich poetów, jak: Szymon Szymonowicz, Szymon Zimorowicz, Jan Gawiński, Samuel Twardowski czy Adrian Wieszczycki omawia etap kształtowania się konwencji gatunku sielankowego. Następnie ukazuje zależność pomiędzy zmianami w warunkach literackich i kulturowych oraz tych, które zaszły w percepcji czytelników, a ich wpływem na ewolucję ustalonej konwencji. Obserwowane zmiany w obrębie konwencji zostały opracowane w odniesieniu do koncepcji substratu gatunko…

The Myristoylated Alanine-Rich C-Kinase Substrate (MARCKS) is Sequentially Phosphorylated by Conventional, Novel and Atypical Isotypes of Protein Kin…

1995

The myristoylated alanine-rich C-kinase substrate (MARCKS) is the major protein kinase C (PKC) substrate in many cell types including fibroblasts and brain cells. Here we describe the phosphorylation of MARCKS and the site specificity for different PKC isotypes. Conventional (c)PKC beta 1, novel (n)PKC delta and nPKC epsilon efficiently phosphorylated the MARCKS protein in vitro. The Km values were extremely low, reflecting a high affinity between kinases and substrate. The apparent affinity of nPKC delta (Km = 0.06 microM) was higher than that of nPKC epsilon and cPKC beta 1 (Km = 0.32 microM). The rate of substrate phosphorylation was inversely correlated with affinity and decreased in th…

Influence of oxide substrates on monolayer graphene doping process by thermal treatments in oxygen

2019

Abstract The structural and the electronic properties of monolayer graphene made by chemical vapor deposition and transferred on various oxide substrates ( SiO 2 , Al 2 O 3 , and HfO 2 ) are investigated by Raman Spectroscopy and Atomic Force Microscopy in order to highlight the influence of the substrate on the features of p-doping obtained by O 2 thermal treatments. By varing the treatment temperature up to 400 °C, the distribution of the reaction sites of the substrates is evaluated. Their total concentration and the consequent highest doping available is determined and it is shown that this latter is linked to the water affinity of the substrate. Finally, by varing the exposure time to …

Potential of an Exploitation of Acid-Tolerant Antimicrobial Microorganisms Evolving Enzyme Systems for the Utilization of Dairy By-products and Ligno…

2016

Genetic and environmental aspect of polycystic ovary syndrome.

2004

Polycystic ovary syndrome (PCOS) is a heterogeneous syndrome determined in most patients by the association of two main factors: hyperandrogenism and insulin resistance. These characters are probably independent of each other and seem to be inherited by several different mechanisms. In some patients homozygous gene alteration has been found but in most patients PCOS seems to be determined by the association of gene polymorphisms that are common in the general population but alone are unable to determine phenotypic consequences. Alteration of genes that regulate the initial steps of ovarian steroidogenesis is probably the main causal factor of hyperandrogenism. Insulin resistance may be the …

The estrogen receptor α:insulin receptor substrate 1 complex in breast cancer: structure–function relationships

2007

Background: Insulin receptor substrate 1 (IRS-1) is a signaling molecule that exerts a key role in mediating cross talk between estrogen receptor a (ERa) and insulin-like growth factor 1 (IGF-1) in breast cancer cells. Previously, we demonstrated that a fraction of IRS-1 binds ERa, translocates to the nucleus, and modulates ERa-dependent transcription at estrogen response elements (ERE). Here, we studied structure-function relationships of the ER-a:IRS-1 complex under IGF-1 and/or estradiol (E 2 ) stimulation. Materials and methods: ERa and IRS-1 deletion mutants were used to analyze structural and functional ERα/IRS-1 interactions. IRS-1 binding to ERE and IRS-1 role in ERa-dependent ERE t…