Search results for " San"
showing 10 items of 3080 documents
Effect of a co-substrate supply in a MBR treating shipboard slop: Analysis of hydrocarbon removal, biomass activity and membrane fouling tendency
2018
The paper reports the main results of an experiment carried out on a membrane bioreactor (MBR) plant designed for the treatment of shipboard slops. With a view of a co-treatment process of the slop with other wastewaters, sodium acetate, as external co-substrate, was supplied (high dosage – Period 1, low dosage – Period 2) to evaluate its effects on hydrocarbons removal. The MBR pilot plant enabled approximately 99% of total petroleum hydrocarbon (TPH) removal during the entire experiment, confirming the robustness of the MBR technology for the treatment of slops. The chromatography/mass spectrometry analysis showed that the removal efficiency for each alkane was close to the value observed…
Polymorphisms within the ARNT2 and CX3CR1 Genes Are Associated with the Risk of Developing Invasive Aspergillosis.
2020
Invasive aspergillosis (IA) is a life-threatening infection that affects an increasing number of patients undergoing chemotherapy or allo-transplantation, and recent studies have shown that genetic factors contribute to disease susceptibility. In this two-stage, population-based, case-control study, we evaluated whether 7 potentially functional single nucleotide polymorphisms (SNPs) within the ARNT2 and CX3CR1 genes influence the risk of IA in high-risk hematological patients. We genotyped selected SNPs in a cohort of 500 hematological patients (103 of those had been diagnosed with proven or probable IA), and we evaluated their association with the risk of developing IA. The association of …
Management of Ponatinib in Patients with Chronic Myeloid Leukemia with Cardiovascular Risk Factors
2019
Cardiovascular (CV) adverse events are considered common complications of ponatinib treatment. Recently, it has been demonstrated that ponatinib dose reductions in definite settings can obtain optimal responses and lower ponatinib-related CV events. In this study, we describe the management of 5 patients with chronic myeloid leukemia treated with ponatinib, from second to fourth line of tyrosine kinase inhibitor therapy, carrying high pre-ponatinib CV risk, who obtained optimal molecular response and developed no CV adverse event during follow-up. Among these 5 patients, 2 had diagnosis of ischemic heart disease and underwent percutaneous angioplasty, 2 had type 2 diabetes and arterial hype…
Current concepts in the prevention of pathogen transmission via blood/plasma-derived products for bleeding disorders
2015
The pathogen safety of blood/plasma-derived products has historically been a subject of significant concern to the medical community, Measures such as donor selection and blood screening have contributed to increase the safety of these products, but pathogen transmission does still occur. Reasons for this include lack of sensitivity/specificity of current screening methods, lack of reliable screening tests for some pathogens (e.g. prions) and the fact that many potentially harmful infectious agents are not routinely screened for. Methods for the purification/inactivation of blood/plasma-derived products have been developed in order to further reduce the residual risk, but low concentrations…
Ubiquitous Structural Signaling in Bacterial Phytochromes
2015
The phytochrome family of light-switchable proteins has long been studied by biochemical, spectroscopic and crystallographic means, while a direct probe for global conformational signal propagation has been lacking. Using solution X-ray scattering, we find that the photosensory cores of several bacterial phytochromes undergo similar large-scale structural changes upon red-light excitation. The data establish that phytochromes with ordinary and inverted photocycles share a structural signaling mechanism and that a particular conserved histidine, previously proposed to be involved in signal propagation, in fact tunes photoresponse.
Continuous and discontinuous nominal expressions in flexible (or “free”) word order languages: Patterns and correlates
2020
AbstractThis study explores continuous and discontinuous word order patterns of multi-word nominal expressions in flexible word order languages (traditionally referred to as “free word order” or “non-configurational” languages). Besides describing syntagmatic patterns, this paper seeks to identify any functional or other correlates that can be associated with different word orders. The languages under investigation are a number of Australian languages as well as Vedic Sanskrit, all of which have long been known for their syntagmatic flexibility. With respect to continuous order, evidence from several of these languages suggests that default ordering is primarily governed by functional templ…
Spatio-temporal deixis and cognitive models in early Indo-European
2018
AbstractThis paper is a comparative study based on the linguistic evidence in Vedic Sanskrit and Homeric Greek, aimed at reconstructing the space-time cognitive models used in the Proto-Indo-European language in a diachronic perspective. While it has been widely recognized that ancient Indo-European languages construed earlier (and past) events as in front of later ones, as predicted in the Time-Reference-Point mapping, it is less clear how in the same languages the passage took place from this ‘archaic’ Time-RP model or non-deictic sequence, in which future events are behind or follow the past ones in a temporal sequence, to the more recent ‘post-archaic’ Ego-RP model that is found only fr…
A Tool to Assess Architectural Education from the Sustainable Development Perspective and the Students' Viewpoint
2021
[EN] Architectural education plays a fundamental role in achieving sustainable development by training future professionals who can contribute to sustainability through their practice. Nevertheless, to ensure the introduction of sustainable development in the education of future architects, it is fundamental to understand what is being done and what could be improved. Despite this, a big gap has been detected in the assessment of architectural education in Spain and worldwide. Thus, a close-ended questionnaire for students has been designed based on the outcomes from a literature review, exploratory interviews with specialists, and the qualitative analysis of two schools of architecture. Ad…
Luigi La Vista, Scritti, vol. I, Studi Storici
2011
"Katajaisen kansan hullut huhut - kansa katu- ja kyläojissa" : Helsingin Sanomien, Raittiussanomien ja Alkoholipolitiikka- aikakauskirjan kirjoittelu…
2012
Tutkin työssäni vuonna 1968 päätetyn alkoholilain ja erillisen keskiolutlain ympärillä käytyä julkista keskustelua. Tarkastelen Raittiussanomien, Helsingin Sanomien ja Alkoholipolitiikka-aikakauskirjan kirjoittelua vuosina 1967 - 1968, jolloin uudet lait olivat eduskuntakäsittelyssä. Tutkimani kirjoitukset pyrkivät vaikuttamaan työn alla olleeseen lainsäädäntöön ja kansanedustajien mielipiteisiin lakiäänestyksen lähetessä. Helsingin Sanomat ja Alkoholipolitiikka osoittautuivat uusien lakien voimakkaiksi kannattajiksi ja läpiajajiksi, kun taas Raittiussanomien rooliksi jäi raittiusaatteen puolustaminen altavastaajan asemasta. Diskurssianalyysin välineillä pyrin löytämään keinoja kuinka omaa …