Search results for " Second"
showing 10 items of 1396 documents
SLIT's Prevention of the Allergic March.
2018
PURPOSE OF REVIEW: The progression of atopic disorders from atopic dermatitis in infants to allergic rhinitis and asthma in children, adolescents, and adults defines the allergy march. Allergen immunotherapy is the only causal treatment altering the immunological mechanism underlying the allergic diseases. The sublingual administration route is more acceptable than the subcutaneous one in pediatric age. RECENT FINDINGS: Several studies show the efficacy and safety profile of sublingual immunotherapy (SLIT) for the treatment of respiratory allergy diseases, but few data are available on its effect of primary and secondary prevention of allergic disease. The purpose of this manuscript is to r…
Nasal IgE in subjects with allergic and non-allergic rhinitis
2020
Abstract Purpose The prevalence of "ocal allergic rhinitis" within individuals suffering from perennial rhinitis remains uncertain, and patients usually are diagnosed with non-allergic rhinitis. The aim of this study was to evaluate the prevalence of a potential "local allergic rhinitis" in subjects suffering from non-allergic rhinitis in a non-selected group of young students. Methods 131 students (age 25.0 ± 5.1 years) with a possible allergic rhinitis and 25 non-allergic controls without rhinitis symptoms (age 22.0 ± 2.0 years) were recruited by public postings. 97 of 131 students with rhinitis were tested positive (≥3 mm) to prick testing with 17 frequent allergens at visit 1. Twenty-fo…
A systematic review and meta-analysis on the effectiveness of xenograft to prevent periodontal defects after mandibular third molar extraction.
2021
Background To evaluate the use of guided bone regeneration with xenograft to prevent periodontal defect in the distal aspect of the second molar after the surgical removal of the mandibular third molar. Material and Methods Three electronic databases (Pubmed, Cochrane Library and Scopus) were searched in April 2020. Randomized clinical trials in non-smokers and healthy patients, with at least six months follow-up, comparing periodontal probing depth, clinical attachment level, alveolar bone level and adverse events were selected by two independent investigators. The risk of bias assessment of the selected studies was evaluated by means of the Cochrane Collaboration’s Tool. Finally, a meta-a…
Governare il Mezzogiorno. Gli alleati e l'occupazione/liberazione del Sud (1943-1945)
2015
In winter 1943 the United Stated and Britain planned the invasion of Axis-held Europe and decided to invade Sicily. A Military Government (Amgot) – which would be a model for the future Allied administration in Europe – was set in order to administrate the occupied territories. While the Allied propaganda presented the invasion of Italy as a «liberation» from the Axis yoke, when in summer 1943 the Allied troops landed in Sicily, Italy was actually treated as a fully-fledged enemy country. When the Amgot became operative, the contradictory role of the Allies in the occupation emerged clearly. The aim of this article is to examine the complex aspects of this military occupation in Sicily an…
Amyloid Fibrils Formation of Concanavalin A at Basic pH
2011
Mechanisms of partial unfolding and aggregation of proteins are of extreme interest in view of the fact that several human pathologies are characterized by the formation and deposition of protein-insoluble material, mainly composed of amyloid fibrils. Here we report on an experimental study on the heat-induced aggregation mechanisms, at basic pH, of concanavalin A (ConA), used as a model system. Thioflavin T (ThT) fluorescence and multiangle light scattering allowed us to detect different intertwined steps in the formation of ConA aggregates. In particular, the ThT fluorescence increase, observed in the first phase of aggregation, reveals the formation of intermolecular β-sheet structure wh…
Decoding vibrational states of Concanavalin A amyloid fibrils.
2015
International audience; Amyloid and amyloid-like fibrils are a general class of protein aggregates and represent a central topic in life sciences for their involvement in several neurodegenerative disorders and their unique mechanical and supramolecular morphological properties. Both their biological role and their physical properties, including their high mechanical stability and thermodynamic inertia, are related to the structural arrangement of proteins in the aggregates at molecular level. Significant variations may exist in the supramolecular organization of the commonly termed cross-β structure that constitutes the amyloid core. In this context, a fine knowledge of the structural deta…
Cholesterol facilitates interactions between α‐synuclein oligomers and charge‐neutral membranes
2015
AbstractOligomeric species formed during α-synuclein fibrillation are suggested to be membrane-disrupting agents, and have been associated with cytotoxicity in Parkinson’s disease. The majority of studies, however, have revealed that the effect of α-synuclein oligomers is only noticeable on systems composed of anionic lipids, while the more physiologically relevant zwitterionic lipids remain intact. We present experimental evidence for significant morphological changes in zwitterionic membranes containing cholesterol, induced by α-synuclein oligomers. Depending on the lipid composition, model membranes are either unperturbed, disrupt, or undergo dramatic morphological changes and segregate …
A rare case of Prinzmetal angina 3 days after coronary artery stenting with a second-generation drug-eluting stent
2015
Non previsto.
Biskup Würzburga Johann Philipp von Schönborn we francuskojęzycznej korespondencji Charlesa II i Jamesa II Stuartów z lat 1652-1673
2021
Podpisany w 1648 r. pokój westfalski nie kończył zmagań wojennych w Europie Zachodniej. Do 1658 r. trwała wojna francusko-hiszpańska, a po drugiej stronie kanału La Manche Anglia targana była najpierw wojną domową, a potem, pod władzą Oliwera Cromwella, uwikłała się w konflikt z Holandią (1652–1654), który stanowił jedynie preludium do kolejnych wojen między tymi państwami. Kluczową rolę w dobie zmagań z Niderlandami odgrywała Rzesza Niemiecka, gdzie jedną z czołowych postaci był biskup Würzburga (arcybiskup Moguncji) Johann Philipp von Schönborn. W planach politycznych uwzględniali go dyplomaci francuscy i habsburscy. O zainteresowaniu Anglików jego osobą świadczą listy Charlesa II i James…
Self-assembly of 3,5-bis(ethoxycarbonyl)pyrazolate anions and ammonium cations of β-phenylethylamine or homoveratrylamine into hetero-double-stranded…
2009
Hydrogen-bonded double-stranded hetero-helices are formed when reacting sodium 3,5-bis(ethoxycarbonyl)pyrazolate with beta-phenethylammonium or homoveratrylammonium chloride, in which one of the strands is defined by the ammonium cations and the other one by the pyrazolate anions.