Search results for " Second"
showing 10 items of 1396 documents
NEAR INFRARED PICOSECOND PULSED BACKWARD SECOND-HARMONIC-GENERATION IN PERIODICALLY-POLED LITHIUM NIOBATE
2011
We report on backward second-harmonic-generation in bulk periodically-poled congruent lithium niobate with a 3.2μm period. A picosecond pulsed laser allowed us exciting a resonance at 1722nm. The resonances were also resolved by temperature tuning.
Caractérisation du mobilier métallique des quartiers artisanaux est et ouest du vicus gallo-romain de Bliesbruck (Moselle)
2014
International audience
Association of low 25-hydroxyvitamin D concentrations with elevated parathyroid hormone concentrations and low cortical bone density in early puberta…
2003
Background: Very few studies have evaluated both parathyroid hormone (PTH) and 25-hydroxyvitamin D [25(OH)D] and their effects on bone mass in children. Objective: We studied the associations of serum 25(OH)D and intact PTH (iPTH) with bone mineral content (BMC) and bone mineral density (BMD) at different bone sites and the relation between serum 25(OH)D and iPTH in early pubertal and prepubertal Finnish girls. Design: The subjects were 10‐12-y-old girls (n = 193) at Tanner stage 1 or 2, who reported a mean (± SD) dietary calcium intake of 733 ± 288 mg/d. 25(OH)D, iPTH, tartrate-resistant acid phosphatase 5b (TRAP 5b), urinary calcium excretion, BMC, areal BMD, and volumetric BMD were asses…
Synthesis and Structure-Activity Relationships of Amino Acid Conjugates of Cholanic Acid as Antagonists of the EphA2 Receptor
2013
The Eph–ephrin system plays a critical role in tumor growth and vascular functions during carcinogenesis. We had previously identified cholanic acid as a competitive and reversible EphA2 antagonist able to disrupt EphA2-ephrinA1 interaction and to inhibit EphA2 activation in prostate cancer cells. Herein, we report the synthesis and biological evaluation of a set of cholanic acid derivatives obtained by conjugation of its carboxyl group with a panel of naturally occurring amino acids with the aim to improve EphA2 receptor inhibition. Structure-activity relationships indicate that conjugation of cholanic acid with linear amino acids of small size leads to effective EphA2 antagonists whereas …
Improving Textual Competence in a Second Language Initial Literacy Classroom
2019
The paper aims to illustrate some textual learning activities developed for an L2 Italian initial-literacy classroom, and, in particular, for illiterate plurilinguals (mostly unaccompanied foreign minors). The activities in question belong to an experimental proposal that consists of a specific textual teaching module integrated with a second-language initial literacy course employing the communicative/affective-humanistic teaching approach. Textual activities are normally proposed to intermediate and advanced level literacy learners in second- language classrooms, in order to fully develop reading and writing abilities (i.e. functional literacy). However, based on the importance of learner…
Metal ions modulate thermal aggregation of betalactoglobulin: a join chemical and physical characterization
2014
Abstract Molecular basis of the role played by Cu 2 + and Zn 2 + ions during the thermal aggregation processes of beta-lactoglobulin (BLG) was studied by using a joint application of different techniques. In particular, Raman spectroscopy was very useful in identifying the different effects caused by the two metals at molecular level (i.e. changes in His protonation state, disulfides bridge conformation, and micro-environment of aromatic residues), evidencing the primary importance of the protein charge distribution during the aggregation process. Both metal ions are able to act on this factor and favor the protein aggregation, but Zn 2 + is able to alter the natural conformational state of…
Bioinformatic flowchart and database to investigate the origins and diversity of Clan AA peptidases
2009
Abstract Background Clan AA of aspartic peptidases relates the family of pepsin monomers evolutionarily with all dimeric peptidases encoded by eukaryotic LTR retroelements. Recent findings describing various pools of single-domain nonviral host peptidases, in prokaryotes and eukaryotes, indicate that the diversity of clan AA is larger than previously thought. The ensuing approach to investigate this enzyme group is by studying its phylogeny. However, clan AA is a difficult case to study due to the low similarity and different rates of evolution. This work is an ongoing attempt to investigate the different clan AA families to understand the cause of their diversity. Results In this paper, we…
Kształtowanie się ustroju II Rzeczpospolitej w aspekcie zrównoważonego rozwoju
2018
W artykule przedstawiono proces kształtowania się ustroju II Rzeczpo-spolitej i pokładanych nadziei na zrównoważony rozwój kraju. Zarysowano tradycjępolskiego parlamentaryzmu i wskazano na jego odrębność względem parlamentary-zmów innych krajów europejskich. Do tradycji tej usiłowało nawiązać odradzające siępo zaborach państwo polskie, przystosowując ją do struktury prawnej nowożytnego państwa liberalno-demokratycznego. Wejście II Rzeczpospolitej do grona państw po-siadających liberalno-demokratyczną konstytucję nie oznaczało, automatycznego za warstwą prawną, przeniesienia struktury społecznej, ekonomicznej i mentalnej. W centrum rozważań znalazła się także Konstytucja Marcowa oraz relacje…
“How are you, siihen me sanotaan I’m fine” : tapaustutkimus oppilaiden ja kielenopettajan käsityksistä kielestä ja kielen oppimisesta varhaisen engla…
2022
Vuonna 2020 Suomessa käynnistettiin uudenlaisen pohjan luominen kielen oppimisen jatkumolle, kun ensimmäisen vieraan tai toisen kotimaisen kielen aloitus varhennettiin ensimmäiselle vuosiluokalle. Tutkimus on osoittanut, että opettajien ja oppilaiden käsityksillä on keskeinen rooli oppimis- ja opetuskäytänteiden muotoutumisessa ja siksi on tärkeää tutkia käsityksiä uudessa tilanteessa. Tässä artikkelissa tarkastellaan yhden englannin aineenopettajan ja hänen oppilaidensa käsityksiä vuosina 2020–2021 tehtyjen teemahaastattelujen kautta. Tulokset osoittivat, että oppilaiden ja opettajan käsityksissä lasten vapaa-ajan ja koulun englanti erosivat toisistaan ja opettajan käsityksissä myös varhai…
Les formations professionnnelles tertiaires : concurrence ou complémentarité
1999
Actes des XIXè journées de l'AES; International audience; Le recouvrement des enseignements du ministère de l'Agriculture avec ceux de l'Education nationale s'est progressivement accru et pose, actuellement, au niveau politique, la question de la légitimité de l'enseignement agricole. Ce texte présente les résultats d'une recherche sur la concurrence ou la complémentarité des deux formations préparant aux métiers des services aux personnes, relevant de chaque ministère.