Search results for " Selectivity"

Organizational justice, sickness absence and employee age

2013

Purpose – The aim of this paper is to study age-related differences in how perceptions of two forms of organizational justice, i.e. procedural and interactional justice, are related to short (i.e. non-certified) spells and long (i.e. medically certified) spells of sickness absence. Design/methodology/approach – The authors conducted a study on a large sample of Finnish public sector employees (n=37,324), in which they matched employees' 2004 survey data with their records-based sick absences in 2005 and 2006. Findings – The results suggest that age moderates the association between perceptions of procedural justice and long sickness absences after controlling for gender, tenure, occupationa…

Cover Feature: Single Peptide Backbone Surrogate Mutations to Regulate Angiotensin GPCR Subtype Selectivity (Chem. Eur. J. 47/2020)

2020

Synthesis of hexahydrocyclopenta[ij]isoquinolines as a new class of dopaminergic agents.

2014

In this study, we have described the synthesis of the tricyclic 1,2,3,7,8,8a-hexahydrocyclopenta [ij]isoquinoline (HCPIQ). Herein, six differently substituted 5,6-dioxygenated-7-phenyl-HCPIQs have been synthesized using a new methodology via (E)-1-styryl-THIQ by Friedel-Crafts cyclization with Eaton's reagent. Results showed that HCPIQs (3, 3a-e) displayed a moderate affinity for D1 dopamine receptors (DR) in the micromolar range, furthermore the catecholic HCPIQs 3a (NH), 3c (NCH3) and 3e (NCH2CHCH2) exhibited outstanding affinity and high selectivity towards D2 DR. Indeed, 3a, 3c and 3e showed Ki values of 29 nM, 13 nM and 18 nM, respectively, and HCPIQs 3a (NH) and 3c (NCH3) displayed a …

Pyrene-benzoylthiophene Bichromophores as Selective Triplet Photosensitizers.

2006

Combination of the pyrene and benzoylthiophene units constitutes an interesting approach to design bichromophoric photosensitizers with increased intersystem crossing quantum yield and enhanced selectivity. The potential of this strategy has been illustrated in the present work by using a model photoisomerization reaction.

Spatial hole burning in thin-disk lasers and twisted-mode operation.

2018

Spatial hole burning prevents single-frequency operation of thin-disk lasers when the thin disk is used as a folding mirror. We present an evaluation of the saturation effects in the disk for disks acting as end-mirrors and as folding-mirrors explaining one of the main obstacles towards single-frequency operation. It is shown that a twisted-mode scheme based on a multi-order quarter-wave plate combined with a polarizer provides an almost complete suppression of spatial hole burning and creates an additional wavelength selectivity that enforces efficient single-frequency operation.

In-beam spectroscopic studies of shape coexistence and collectivity in the neutron-deficientZ≈ 82 nuclei

2016

In the present paper we focus on studies of shape coexistence in even-mass nuclei in the neutron-deficient Pb region. They are based on experiments carried out using tagging techniques in the Accelerator Laboratory of the University of Jyväskylä, Finland. Excited states in many of these nuclei can only be accessed via fusion-evaporation reactions employing high-intensity stable-ion beams. The key features in these experiments are high selectivity, clean spectra and instrumentation that enables high count rates. We review three spectroscopic highlights in this region. peerReviewed

Human Development from Middle Childhood to Middle Adulthood

2017

This seminal work focuses on human development from middle childhood to middle adulthood, through analysis of the research findings of the groundbreaking Jyvaskyla Longitudinal Study of Personality and Social Development (JYLS). The JYLS project, which began in 1968, has generated extensive publications over many years but this is the first comprehensive summary that presents the conceptual framework, the research design and methodology, and the findings. The study looks at the development over time of issues related to personality, identity, health, anti-social behavior, and well-being and is unparalleled in its duration, intensity, comprehensiveness and psychological richness. The thoroug…

Identity Formation, Personal Control Over Development, and Well-Being

2006

Individuals' conceptions of their personal goals have been studied in the psychology literature from different perspectives. In this chapter, the processes and implications of one's orientations and self-definitions were analyzed along two dimensions: one's sense of identity, and the self-percepts of autonomous control over development. Several researchers (e.g., Archer, 1989; Brandtstädter & Baltes-Götz, 1990; Pulkkinen & Rönkä, 1994) have concluded, on the basis of literature reviews and empirical findings, that adaptive capacities are associated with a clear sense of identity and personal control over development. Although any given cultural and historical context confines the possible a…

Pesticides: Chemical and Biological.

2013

There is a requirement by World Health Organization (WHO), Food and Agriculture Organization (FAO) and other International Organizations to develop environmentally sustainable systems for controlling pests that are less reliant on chemical pesticides as the primary management tool. However biological control alone cannot at the moment solve all pest problems and must be considered instrument to be used in combination with other methods. Compatibility of chemical pesticides (CP) and biological pesticides (BP) is one of the key for the implementation of Integrated Pest Management (IPM) programs. Testing the compatibility of CP and BP is necessary if these two agents are to be applied together…

2020

Abstract Challenge is a key motivation for videogame play. But what kind of challenge types videogames include, and which of them players prefer? This article helps to answer the above questions by developing and validating Videogame Challenge Inventory (CHA), a psychometrically sound measurement for investigating players’ challenge preferences in videogames. Based on a review of literature, we developed a 38-item version of CHA that was included in a social media user survey (N = 813). An exploratory factor analysis (EFA) revealed a latent structure of five challenge types: Physical, Analytical, Socioemotional, Insight, and Foresight. CHA was amended in another EFA with USA-based survey da…