Search results for " Sexual"
showing 10 items of 475 documents
Gonadal sexual differentiation of European sea bass (Dicentrarchus labrax, L. 1758) of fingerlings in different size classes
2016
This report describes a study of the gonad differentiation in fingerlings of European sea bass (Dicentrarchus labrax) belonging to different size groups. Fishes were divided into four groups according to their weight: Group 1 (4.5 ± 0.7 g), Group 2 (9.2 ± 0.8 g), Group 3 (14.8 ± 1.8 g), and Group 4 (21.8 ± 2.3 g). In all groups, low percentages of undifferentiated or early sexually differentiated fish were found. Higher percentages of fully differentiated ovaries were found in Groups 1 and 3. Fully differentiated testes occurred in 90% of Group 4. Ninety percent of fish in Group 2 had gonads with intratesticular oocytes. This highlights the occurrence of intersexual cases and suggests that …
Linear biocompatible glyco-polyamidoamines as dual action mode virus infection inhibitors with potential as broad-spectrum microbicides for sexually …
2016
AbstractThe initial steps of viral infections are mediated by interactions between viral proteins and cellular receptors. Blocking the latter with high-affinity ligands may inhibit infection. DC-SIGN, a C-type lectin receptor expressed by immature dendritic cells and macrophages, mediates human immunodeficiency virus (HIV) infection by recognizing mannose clusters on the HIV-1 gp120 envelope glycoprotein. Mannosylated glycodendrimers act as HIV entry inhibitors thanks to their ability to block this receptor. Previously, an amphoteric, but prevailingly cationic polyamidoamine named AGMA1 proved effective as infection inhibitor for several heparan sulfate proteoglycan-dependent viruses, such …
Evaluation of HIV transmission clusters among natives and foreigners living in Italy
2020
We aimed at evaluating the characteristics of HIV-1 molecular transmission clusters (MTCs) among natives and migrants living in Italy, diagnosed between 1998 and 2018. Phylogenetic analyses were performed on HIV-1 polymerase (pol) sequences to characterise subtypes and identify MTCs, divided into small (SMTCs, 2&ndash
Origin of modern syphilis and emergence of a pandemic Treponema pallidum cluster
2016
The abrupt onslaught of the syphilis pandemic that started in the late fifteenth century established this devastating infectious disease as one of the most feared in human history1 . Surprisingly, despite the availability of effective antibiotic treatment since the mid-twentieth century, this bacterial infection, which is caused by Treponema pallidum subsp. pallidum (TPA), has been re-emerging globally in the last few decades with an estimated 10.6 million cases in 2008 (ref. 2). Although resistance to penicillin has not yet been identified, an increasing number of strains fail to respond to the secondline antibiotic azithromycin3. Little is known about the genetic patterns in current infec…
Identification of a large, fast-expanding HIV-1 subtype B transmission cluster among MSM in Valencia, Spain
2017
We describe and characterize an exceptionally large HIV-1 subtype B transmission cluster occurring in the Comunidad Valenciana (CV, Spain). A total of 1806 HIV-1 protease-reverse transcriptase (PR/RT) sequences from different patients were obtained in the CV between 2004 and 2014. After subtyping and generating a phylogenetic tree with additional HIV-1 subtype B sequences, a very large transmission cluster which included almost exclusively sequences from the CV was detected (n = 143 patients). This cluster was then validated and characterized with further maximum-likelihood phylogenetic analyses and Bayesian coalescent reconstructions. With these analyses, the CV cluster was delimited to 11…
Trichomonicidal and parasite membrane damaging activity of bidesmosic saponins from Manilkara rufula.
2017
The infection caused by Trichomonas vaginalis is the most common but overlooked non-viral sexually transmitted disease worldwide. Treatment relies on one class of drugs, the 5-nitroimidazoles, but resistance is widespread. New drugs are urgently needed. We reported the effect of crude and purified saponin fractions of Manilkara rufula against Trichomonas vaginalis. The compound responsible for antitrichomonal activity was isolated and identified as an uncommon bidesmosic saponin, Mi-saponin C. This saponin eliminated parasite viability without toxicity against the human vaginal epithelial line (HMVII). In addition, the isolated saponin fraction improved the metronidazole effect against a me…
Minors and Transexuality
2020
[ES] En el ámbito de la transexualidad los poderes públicos han ejercido desde un principio una política claramente restrictiva que ha requerido de años para poder abrirse a las nuevas necesidades y a la sociedad actual. Así, la normativa en la materia era totalmente excluyente de los menores de edad, considerándolos carentes de aptitud alguna para poder decidir sobre su identidad sexual y todo lo que ello conllevaba, quizá porque como afirman algunos autores “la finalidad básica de esa prohibición es la de garantizar que la decisión de la rectificación registral sea una decisión firme y coherente, evitando así cambios arbitrarios o no fundados en el sexo” (Vázquez-Pastor, 2010).Esta idea p…
Infecciones de transmisión sexual en población joven ¿qué mantiene su exposición al riesgo?
2019
Las infecciones de transmisión sexual, suponen uno de los riesgos más prevalentes entre lapoblación joven. En España, su incidencia se ha incrementado en los últimos años, siendo uno los países más afectados de Europa. Si bien se han llevado a cabo distintos esfuerzos preventivos para revertir la situación, no han mostrado la eficacia esperada. Por eso, resulta necesario profundizar en el análisis de aquellos factores que podrían mantener las conductas de riesgo. Así pues, el objetivo del presente estudio es evaluar el papel de factores psicológicos en la prevención de infecciones de transmisión sexual entre población joven. Para ello, 984 jóvenes de entre 18 y 24 años (32,7% hombres y 67,3…
CONOCIMIENTOS, COMPORTAMIENTO Y ACTITUDES SEXUALES EN ADULTOS CON DISCAPACIDAD INTELECTUAL
2014
Abstract:KNOWLEDGE, ATTITUDES AND SEXUAL BEHAVIOR IN ADULTS WITH INTELLECTUAL DISABILITIESThis paper conducts an exploratory study whose overall objective is to analyze sexual behavior, level of knowledge and attitudes about safe sex practices in a sample of people with intellectual disabilities to prevent sexual violence against this group. The sample is composed of 78 people (39 men and 39 women) with a mild or moderate intellectual disability. The results obtained through a structured interview indicate that the level of knowledge about sexual practices highlights that 73.1% had sexual intercourse, 87.4% had knowledge of the different types of contraceptive methods and 56.3% trust the pr…
The experience of sexuality in adults with intellectual disability
2017
Background People with intellectual disability have the same sexual needs as those without any disability, yet their sexuality is often restricted by reluctant attitudes and/or fears based on irrational beliefs. The aim of this study is to describe and analyse different areas of sexuality in adults with mild or moderate intellectual disability. Method The sample consisted of 180 men and 180 women attending occupational centres. All the participants were administered a questionnaire about sexuality adapted to their characteristics. Results Results show that 84.2% have had sexual relationships with another person, this percentage being higher in females and in people aged between 38 and 55 ye…