Search results for " Signals"

showing 10 items of 111 documents

Frequency of polymorphisms of signal peptide of TGF-beta1 and -1082G/A SNP at the promoter region of Il-10 gene in patients with carotid stenosis

2006

The role of inflammation in atherosclerosis is well recognized. We have evaluated the allele frequencies of the +869T/C and +915G/C polymorphisms (SNPs) at the TGF-beta1 gene and -1082G/A SNP at IL-10 promoter sequence, two well-known immunosuppressive and anti-inflammatory cytokines, in patients with carotid stenosis. Our data suggest a lack of association between these SNPs and the susceptibility to atherosclerosis although other reports have demonstrated this association. These results may be due to the pleiotropic effects of the cytokines and/or differences in haplotype combination that should be investigated to elucidate the role of TGF-beta1 and IL-10 polymorphisms in atherosclerosis.

medicine.medical_treatmentSNPSingle-nucleotide polymorphismInflammationProtein Sorting SignalsBioinformaticsPolymorphism Single NucleotideGeneral Biochemistry Genetics and Molecular BiologyTransforming Growth Factor beta1atherosclerosiHistory and Philosophy of ScienceGene FrequencyPolymorphism (computer science)Transforming Growth Factor betacytokineMedicineSNPHumansCarotid StenosisPromoter Regions GeneticAllele frequencyAgedAged 80 and overPolymorphism Geneticbusiness.industryGeneral NeuroscienceHaplotypePromoterSequence Analysis DNAMiddle AgedInterleukin-10carotid stenosiCytokineImmunologyIL-10medicine.symptombusinessTGF-beta 1
researchProduct

GW170817: Observation of Gravitational Waves from a Binary Neutron Star Inspiral

2017

On August 17, 2017 at 12-41:04 UTC the Advanced LIGO and Advanced Virgo gravitational-wave detectors made their first observation of a binary neutron star inspiral. The signal, GW170817, was detected with a combined signal-to-noise ratio of 32.4 and a false-alarm-rate estimate of less than one per 8.0×104 years. We infer the component masses of the binary to be between 0.86 and 2.26 M, in agreement with masses of known neutron stars. Restricting the component spins to the range inferred in binary neutron stars, we find the component masses to be in the range 1.17-1.60 M, with the total mass of the system 2.74-0.01+0.04M. The source was localized within a sky region of 28 deg2 (90% probabili…

neutron star: binary[ PHYS.ASTR ] Physics [physics]/Astrophysics [astro-ph]X-ray binaryADVANCED LIGOAstrophysicsKilonovagravitational waves; LIGO; binary neutron star inspiralspin01 natural sciencesLIGOGeneralLiterature_REFERENCE(e.g.dictionariesencyclopediasglossaries)QCQBHigh Energy Astrophysical Phenomena (astro-ph.HE)Electromagnetic observationsGravitational-wave signals3100 General Physics and AstronomyPoint MassesAstrophysics - High Energy Astrophysical PhenomenaBlack-Hole MergersBinary neutron starsBlack HolesX-ray bursterCoalescing BinariesAstrophysics::High Energy Astrophysical Phenomena10192 Physics InstituteGeneral Relativity and Quantum Cosmology (gr-qc)Gravity wavesGravitational wavesNeutron starsPhysics and Astronomy (all)ddc:530Electromagnetic spectraNeutrons010308 nuclear & particles physicsVirgoGamma raysAstronomyRCUKVIRGOelectromagneticgravitational radiation: emissionStellar black holeGamma-ray burst[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]Compact Binariesbinary: masscosmological modelAstronomyGeneral Physics and AstronomyAstrophysicsneutron starsGamma ray burstsGeneral Relativity and Quantum CosmologyGravitational wave detectorsUniverseDENSE MATTER010303 astronomy & astrophysicsastro-ph.HEPhysicsSignal to noise ratioSettore FIS/01 - Fisica SperimentaleGravitational effectsFalse alarm rateEQUATION-OF-STATEMergers and acquisitionsgravitational waves[PHYS.GRQC]Physics [physics]/General Relativity and Quantum Cosmology [gr-qc]530 PhysicsMERGERSGeneral Relativity and Quantum Cosmology; General Relativity and Quantum Cosmology; astro-ph.HEFOS: Physical sciencesAstrophysics::Cosmology and Extragalactic Astrophysicsgamma ray: burstgravitational radiation: direct detectionMerging[ PHYS.GRQC ] Physics [physics]/General Relativity and Quantum Cosmology [gr-qc]GAMMA-RAY BURSTLIGO (Observatory)binary: coalescenceGravitational waves neutron stars gamma-ray burst LIGO Virgo0103 physical sciencesGW151226MASSESSTFCAstrophysics::Galaxy AstrophysicsPhysiqueGravitational wavegravitational radiationPULSARgravitational radiation detectorNeutron starPhysics and AstronomygravitationRADIATIONDewey Decimal Classification::500 | Naturwissenschaften::530 | Physikbinary neutron star inspiralSignal detectionPHYS REV LETT PHYSICAL REVIEW LETTERS
researchProduct

Early warning system in logistics project management

2017

Risk management is a vital process in all complex logistics project management. We discuss the concept of early warning system EWS dedicated to logistics project, which enable management under the conditions of uncertainty and risk. The complexity and uniqueness of the logistics projects as well as the discontinuity of the effects in the environment of goods and services, significantly impact the inability to eliminate the risks and subsequently lead to changes during execution. The introduction into companies and supply chains things such as: principles, methods, mechanisms of knowledge management and project risk, e.g. by implementing into the logistics project management the early warnin…

project managementweak signalsEarly warning systemlogistics projectuncertaintyrisk
researchProduct

Stakeholder Analysis as a Source of Early Warning Signals in Logistics Projects

2017

Logistics projects are undertaken by a set of multiple organizations that engage resources from different logistics systems, production systems, management systems, social-cultural systems. They are subject to impact of wider economic and political environments. Logistics projects involve participants from diverse cultural environments, management practice. The article presents the essence and importance of stakeholders in projects including logistics projects. The author presents the basic issues related to stakeholders and early warning concept in project management. The specific research question is: How to implement the stakeholder relations management in early warning system dedicated …

projectstakeholder relationship managementlogistics projectstakeholderearly signalsearly warning systemPrzedsiębiorczość i Zarządzanie
researchProduct

Putative sorting signals involved in PIN1 trafficking

2013

Las auxinas son hormonas vegetales involucradas en muchos procesos fisiológicos, tales como el crecimiento y diferenciación celular, la maduración de los frutos, la floración o los tropismos. Su transporte a través de la planta es polar, jugando un papel esencial en la regulación del crecimiento y el desarrollo y contribuyendo al mantenimiento de la polaridad global de la planta. La polaridad en el flujo de auxinas es debida, al menos en parte, a la distribución polar de los transportadores de salida de auxina de la familia PIN. En Arabidopsis thaliana se han identificado 8 transportadores PIN diferentes. Todos ellos presentan una estructura similar, con un dominio citosólico central que se…

sorting signalstráfico intracelularintracellular traffickingUNESCO::CIENCIAS DE LA VIDA::Biología molecular::Biología molecular de plantas:CIENCIAS DE LA VIDA::Biología molecular::Biología molecular de plantas [UNESCO]arabidopsis thalianaPINplantclatrinaadaptinsclathrinadaptinasseñales de clasificación
researchProduct

Colour alone matters : no predator generalization among morphs of an aposematic moth

2018

Local warning colour polymorphism, frequently observed in aposematic organisms, is evolutionarily puzzling. This is because variation in aposematic signals is expected to be selected against due to predators' difficulties associating several signals with a given unprofitable prey. One possible explanation for the existence of such variation is predator generalization, which occurs when predators learn to avoid one form and consequently avoid other sufficiently similar forms, relaxing selection for monomorphic signals. We tested this hypothesis by exposing the three different colour morphs of the aposematic wood tiger moth, Arctia plantaginis, existing in Finland to local wild-caught predato…

varoitusväri0106 biological sciences0301 basic medicinepredatorspredator-prey interactionsoppiminengeneralisationta1172ZoologyAposematismBiologywarning coloration010603 evolutionary biology01 natural sciencestäpläsiilikäsgeneettinen monimuotoisuusPredationpolymorphism03 medical and health sciencesArctia plantaginisGeneralization (learning)petoeläimetmatkiminenmothsjäljittelyPredatorEcology Evolution Behavior and Systematicswood tigersaaliseläimetWinglearningCyanistesyöperhosetpredator–prey interactionswood tiger mothbiology.organism_classificationpredator generalization030104 developmental biologywarning signalsMimicryta1181Animal Science and ZoologypreyAnimal Behaviour
researchProduct

Multimodal Aposematic Defenses Through the Predation Sequence

2021

Aposematic organisms warn predators of their unprofitability using a combination of defenses, including visual warning signals, startling sounds, noxious odors, or aversive tastes. Using multiple lines of defense can help prey avoid predators by stimulating multiple senses and/or by acting at different stages of predation. We tested the efficacy of three lines of defense (color, smell, taste) during the predation sequence of aposematic wood tiger moths (Arctia plantaginis) using blue tit (Cyanistes caeruleus) predators. Moths with two hindwing phenotypes (genotypes: WW/Wy = white, yy = yellow) were manipulated to have defense fluid with aversive smell (methoxypyrazines), body tissues with a…

varoitusväri0106 biological sciencesTastepredator-prey interactionsPyrrolizidine alkaloidEvolutiondefense mechanismsmultimodal signalingPREYAVOIDANCEZoologyContext (language use)AposematismITHOMIINE BUTTERFLIESBiology010603 evolutionary biology01 natural sciencestäpläsiilikäsPredation03 medical and health scienceschemistry.chemical_compoundCyanistes caeruleuschemical defensePYRROLIZIDINE ALKALOIDSQH359-425aposematismpuolustusmekanismit (biologia)Arctia plantaginissinitiainenQH540-549.5EDUCATED PREDATORSEcology Evolution Behavior and Systematics030304 developmental biology0303 health sciencesTASTEEcologyfungiCyanistesbiology.organism_classificationsaalistusWARNING COLORATIONCHEMICAL DEFENSEchemistryTRADE-OFFwarning signals1181 Ecology evolutionary biologyPyrrolizidineChemical defensePYRAZINE ODORFrontiers in Ecology and Evolution
researchProduct

Influence of colour, smell and taste on the survival of the wood tiger moth (Arctia plantaginis) adults during predation event

2021

Saalistajien torjumiseksi saalis voi käyttää erilaisia puolustusmekanismeja, jotka stimuloivat useita eri aisteja (ts. multimodaalista signalointia). Esimerkiksi aposemaattiset eliöt puolustautuvat varoitussignaalin lisäksi sekundaarisella puolustuksella. Tässä tutkimuksessa keskityttiin siihen, kuinka täpläsiilikkään (Arctia plantaginis) väritys (genotyypit WW, Wy ovat valkoisia ja yy keltaisia), haju (metoksipyratsiinista) ja maku (pyrrolitsidiinialkaloidista) toimivat puolustuksena lintusaalistajien hyökkäyksiä vastaan. Linnuille tarjottiin kummankin värisiä eläviä siilikkäitä, joita oli manipuloitu niin, että niillä oli joko hajua, makua tai molempia näistä. Näin pystyttiin tutkimaan ku…

varoitusväripredator-prey interactionschemical defencedefence mechanismsyöperhosetwarning colorationalkaloidssaalistusCyanistes caeruleusalkaloiditAposematismmultimodal signallingbirdswarning signalsmothslinnutpredation
researchProduct

Multimodal Aposematic Signals and Their Emerging Role in Mate Attraction

2018

varoitusväriwarning colourationsaaliseläimetsukupuolivalintapredator-prey interactionsparinvalintapetoeläimetmultimodal signalsta1181sexual selectionsignaalitchemical signalssignal variationFrontiers in Ecology and Evolution
researchProduct

Multimodal Aposematic Signals and Their Emerging Role in Mate Attraction

2018

Chemically defended animals often display conspicuous color patterns that predators learn to associate with their unprofitability and subsequently avoid. Such animals (i.e., aposematic), deter predators by stimulating their visual and chemical sensory channels. Hence, aposematism is considered to be “multimodal.” The evolution of warning signals (and to a lesser degree their accompanying chemical defenses) is fundamentally linked to natural selection by predators. Lately, however, increasing evidence also points to a role of sexual selection shaping warning signal evolution. One of the species in which this has been shown is the wood tiger moth, Arctia plantaginis, which we here put forward…

warning colourationvaroitusvärisaaliseläimetpredator-prey interactionssukupuolivalintaparinvalintapetoeläimetmultimodal signalschemical defencessignaalitchemical signalsarcctia plantaginissignal variation
researchProduct