Search results for " Skin"

showing 10 items of 1220 documents

Myocardial 123metaiodobenzylguanidine uptake in genetic Parkinson's disease.

2008

Myocardial (123)Metaiodobenzylguanidine (MIBG) enables the assessment of postganglionic sympathetic cardiac innervation. MIBG uptake is decreased in nearly all patients with Parkinson's disease (PD). Our objective was to evaluate MIBG uptake in patients with genetic PD. We investigated MIBG uptake in 14 patients with PD associated with mutations in different genes (Parkin, DJ-1, PINK], and leucine-rich repeat kinase 2 -LRRK2), in 15 patients with idiopathic PD, and 10 control subjects. The myocardial MIGB uptake was preserved in 3 of the 4 Parkin-associated Parkinsonisms, in I of the 2 patients with DJ-1 mutations, in 1 of the 2 brothers with PINK] mutations, in 3 of the 6 unrelated patient…

AdultMalemedicine.medical_specialtyParkinson's diseaseGenotypeUbiquitin-Protein LigasesDNA Mutational AnalysisProtein Deglycase DJ-1PINK1Gene mutationProtein Serine-Threonine Kinasesmedicine.disease_causeLeucine-Rich Repeat Serine-Threonine Protein Kinase-2Severity of Illness IndexParkinCentral nervous system diseaseDiagnosis DifferentialDegenerative diseaseParkinsonian DisordersInternal medicineSurveys and QuestionnairesmedicineHumansPoint MutationPromoter Regions GeneticGenetic PD Myocardial scintigraphyOncogene ProteinsTomography Emission-Computed Single-PhotonMutationMovement Disordersbusiness.industryMyocardiumIntracellular Signaling Peptides and ProteinsParkinson DiseaseGalvanic Skin ResponseMiddle Agedmedicine.diseaseLRRK2nervous system diseases3-IodobenzylguanidineEndocrinologyNeurologySettore MED/26 - NeurologiaFemaleNeurology (clinical)RadiopharmaceuticalsbusinessProtein KinasesMovement disorders : official journal of the Movement Disorder Society
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A systematic approach to medical decision-making of uncommon clinical pictures: A case of ulcerative skin lesions by palm tree thorn injury and a one…

2005

In clinical practice, the clinician is challenged with symptoms and/or signs at times apparently insoluble by diagnostic and/ or therapeutic means. We propose that in these cases, we have to use an EBM approach in which evidence may be looked up in every available clinical report and bibliographic databases are used for searching that evidence. We report on a case of ulcerative skin lesions apparently insoluble by expert dermatologists following a conventional diagnostic and therapeutic process. We use this case report for illustrating a systematic approach to resolve diagnostic and therapeutic questions using a bibliographic database search (like MEDLINE and EMBASE). Both a systematic appr…

AdultMalemedicine.medical_specialtyPathologyOne year follow upmedical decision-makingMEDLINEDecision MakingAlternative medicineMEDLINEthorn injuryulcerative skin lesionWounds PenetratingHealth InformaticsDiagnosis DifferentialClinical reportHealth Information Managementuncommon clinical picturemedicineHumansIntensive care medicineGeneral NursingLegEvidence-Based Medicinebusiness.industryLeg UlcerMedical decision makingDatabases BibliographicBibliographic databasepalm treeItalyPalmbusinessSkin lesionMedical InformaticsMedical Informatics and the Internet in Medicine
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Parental food-related behaviors and family meal frequencies: associations in Norwegian dyads of parents and preadolescent children.

2012

Background: Frequent family meals are associated with healthy dietary behaviors and other desirable outcomes in children and adolescents. Therefore, increased knowledge about factors that may increase the occurrence of family meals is warranted. The present study has its focus on the home food environment, and aims to explore potential associations between parent-reported feeding behaviors and child-reported family meal frequencies. Methods: Cross-sectional surveys were performed among 10-12-year-olds and their parents recruited from eighteen schools in southwest Norway. The child questionnaire included measures of family meal frequencies (breakfast, dinner and supper). The parent questionn…

AdultMalemedicine.medical_specialtyPediatricsTime FactorsFamily mealsCross-sectional studyChild WelfareNorwegianSocial EnvironmentEatingSurveys and QuestionnairesEpidemiologymedicineHumansParent-Child RelationsChildMealsBreakfastMealParentingbusiness.industryNorwayPublic healthdigestive oral and skin physiologyPublic Health Environmental and Occupational HealthSocial environmentVDP::Medical disciplines: 700::Health sciences: 800Feeding BehaviorMiddle AgedChild eatinglanguage.human_languageFeeding practicesPeer reviewCross-Sectional StudiesMenu PlanningHome food environmentlanguageFemaleBiostatisticsbusinessDemographyResearch ArticleBMC public health
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Gastric emptying of indigestible tablets in relation to composition and time of ingestion of meals studied by metal detector.

1991

Enteric-coated tablets leave the stomach mainly during the interdigestive phase. Composition as well as time of ingestion of meals may influence their gastric emptying considerably. In 12 normal volunteers gastric emptying of a plastic tablet with a metal core was followed by a metal detector in relation to different compositions and various times of ingestion of meals. With an empty stomach and after ingestion of 250 ml water, the mean time for gastric emptying of the tablet was 38 +/- 11 min (mean +/- SEM) and 38 +/- 8 min. Two hundred fifty milliliters of milk (652 kJ) and a formula diet (1000 kJ) delayed gastric emptying time to 128 +/- 14 and 152 +/- 6 min, respectively (P less than 0.…

AdultMalemedicine.medical_specialtyPhysiologyGastroenterologyEatingInternal medicinemedicineIngestionHumansEnteric coatedEating habitsMorningGastric emptyingbusiness.industryStomachdigestive oral and skin physiologyGastroenterologyMiddle AgedBioavailabilitymedicine.anatomical_structureGastric EmptyingFoodMetalsComposition (visual arts)FemaleTablets Enteric-CoatedbusinessDigestive diseases and sciences
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Relationships between electrodermal activity and symptomatology in schizophrenia.

1993

The present report studies the differences between schizophrenic responders and nonresponders within the different symptomatologic groups of the Scale for the Assessment of Negative Symptoms (SANS) and the Scale for the Assessment of Positive Symptoms (SAPS). The relationship between the different electrodermal activity parameters and the scores on the scales was also analyzed. The results showed that nonresponders had negative symptoms. In addition negative symptoms registered a general fall in all electrodermal-activity parameters.

AdultMalemedicine.medical_specialtyPsychosisArousalDelusionSchizophrenic PsychologymedicineHumansPsychiatryScale for the Assessment of Negative SymptomsPsychiatric Status Rating ScalesGalvanic Skin Responsemedicine.diseasePsychiatry and Mental healthClinical PsychologySchizophreniaPsychiatric status rating scalesSchizophreniaFemaleSchizophrenic Psychologymedicine.symptomPsychologySkin conductanceArousalClinical psychologyPsychopathology
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Efficacy, safety and quality of life of calcipotriol/betamethasone dipropionate (Dovobet (R)) versus calcipotriol (Daivonex (R)) in the treatment of …

2007

Objective: A clinical trial was performed to evaluate the efficacy, speed of response, side effects and quality of life of patients treated with calcipotriol/betamethasone dipropionate (Dovobet (R)) for 4 weeks followed by maintenance with calcipotriol for 8 weeks (group A) versus calcipotriol (Daivonex (R)) alone for 12 weeks (group B) for the treatment of psoriasis. Materials and methods: A total of 150 patients were enrolled and randomized to groups A and B. PASI and Skindex-29 were considered the outcome measures. Results: Ninety-six patients completed the trial. At weeks 2 and 4, both groups showed a significant clinical improvement compared to baseline; group A demonstrated a higher c…

AdultMalemedicine.medical_specialtyRandomizationAdolescentskindex-29medicine.drug_classBetamethasone dipropionatecalcipotriol/betamethasone dipropionate; Dovobet; calcipotriol. Daivonex; psoriasis vulgaris; clinical trialDermatologyAdministration CutaneousBetamethasoneSeverity of Illness IndexDrug Administration Schedulelaw.inventionchemistry.chemical_compoundRandomized controlled trialCalcitriolcalcipotriolo/betametasone dipropionatolawPsoriasisInternal medicinepasimedicineHumansPsoriasiscalcipotriolo; calcipotriolo/betametasone dipropionato; pasi; psoriasi; skindex-29CalcipotriolcalcipotriolopsoriasiAgedAged 80 and overAnalysis of Variancebusiness.industrycalcipotriol calcipotriol/betamethasone dipropionate PASI psoriasis Skindex-29 two-compound productMiddle Agedmedicine.diseaseSurgeryClinical trialDrug CombinationsTreatment OutcomechemistryQuality of LifeCorticosteroidBetamethasoneFemaleDermatologic Agentsbusinessmedicine.drug
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A breathing-retraining procedure in treatment of sleep-onset insomnia: theoretical basis and experimental findings.

1995

Increase in CO2 has a sedative effect upon the central nervous system, and the beginning of sleep coincides with modifications in breathing, decrease in ventilation, and in pCO2 increase. In this paper is described a technique of breathing that is useful in producing drowsiness in a very short time. 46 insomniacs were randomly allocated to either a treatment or control condition. In the former, patients were trained in the breathing process. The control group was taught no breathing process. Latencies to sleep for the insomniacs confirmed that the breathing process was useful in producing drowsiness. Theoretical bases are discussed.

AdultMalemedicine.medical_specialtySedative effectExperimental and Cognitive PsychologyBreathing Exercises050105 experimental psychologylaw.invention03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationRandomized controlled triallawSleep Initiation and Maintenance DisordersmedicineInsomniaHumans0501 psychology and cognitive sciencesBreathing retrainingdigestive oral and skin physiology05 social sciences030229 sport sciencesCarbon DioxideSensory SystemsAnesthesiaBreathingFemaleSleep (system call)Sleep Stagesmedicine.symptomSleep onsetPsychologyArousalPerceptual and motor skills
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Total body skin examination for skin cancer screening in patients with focused complaints

2012

Background. The value of total body skin examination (TBSE) for skin cancer screening is controversial. Objective: We sought to determine whether TBSE could be helpful in patients with focused skin symptoms who would not otherwise have undergone TBSE. Methods: In a prospective, multicenter, cross-sectional study consecutive adult patients were recruited during a period of 18 months. Physicians first inspected, problem areas and uncovered areas and then performed TBSE. Equivocal lesions detected in both steps were excised or biopsied. Primary outcomes were the absolute and relative risks of missing skin cancer and the number of patients needed to examine to detect melanoma or another maligna…

AdultMalemedicine.medical_specialtySkin NeoplasmsBiopsyprevalenceDermoscopyPhysical examinationDermatologydermatoscopyMalignancySkin Diseasesskin cancer; dermoscopy; prevention; prevalencetotal body skin examinationpreventionAdult; Aged; Biopsy; Cross-Sectional Studies; Dermoscopy; Early Detection of Cancer; Female; Humans; Male; Middle Aged; Physical Examination; Prospective Studies; Skin Diseases; Skin NeoplasmsBiopsymedicinemelanomaHumansProspective StudiesProspective cohort studyPhysical ExaminationEarly Detection of CancerAgedCross-Sectional StudieDermatoscopyintegumentary systemmedicine.diagnostic_testskin cancerbusiness.industrySkin DiseaseMelanomascreeningpigmented skin lesionsMiddle Agedmedicine.diseaseDermatologyProspective StudieCross-Sectional Studiestotal body skin examination; melanoma; skin cancer; preventionRelative riskFemalenonmelanoma skin cancerdermoscopySkin cancerbusinessHuman
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Habituation and Sensitization Processes in Depressive Disorders

1999

The aim of the present study was to investigate further into habituation and sensitization processes in depressive disorders. The depressive subjects were 27 outpatients. All of them were diagnosed according to DSM-III-R criteria. Controls were 27 normal subjects. The amplitudes of electrodermal responses and the basal levels were recorded during a stimuli series of 15 80-dB tones and of 1 100-dB tone in the 11th trial. The depressive patients displayed lower basal conductance levels and lower conductance amplitudes in orienting responses to the first stimulus and to stimulus change. No differences were found in conductance response amplitudes of stimuli series, although a tendency towards …

AdultMalemedicine.medical_specialtyStimulus (physiology)AudiologyDevelopmental psychologySensitization processmedicineHumansHabituationHabituation PsychophysiologicRepression-SensitizationSensitizationAnalysis of VarianceDepressive DisorderGalvanic Skin ResponseStimulus changePsychiatry and Mental healthClinical PsychologyElectrophysiologymedicine.anatomical_structureFemaleRepression-SensitizationAnalysis of varianceArousalPsychologyPsychopathology
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Latent Tuberculosis Infection among Healthcare Students and Postgraduates in a Mediterranean Italian Area: What Correlation with Work Exposure?

2019

Background: Tuberculosis screening is part of the standard protocol for evaluating the risk of infection in healthcare workers. The aim of this study was to evaluate the prevalence of latent tuberculosis infection (LTBI) among students attending various healthcare profession degree courses and postgraduate medical courses at the School of Medicine of the University of Palermo, Italy, and assess the possible professional origin of infection. Methods: In total, 2946 students (2082 undergraduates and 864 postgraduates) took part in a screening program for LTBI between January 2014 to April 2019 using the tuberculin skin test (TST). Students with a positive TST result underwent a Quantiferon-TB…

AdultMalemedicine.medical_specialtyStudents MedicalSettore MED/17 - Malattie InfettiveHealth PersonnelHealth Toxicology and MutagenesiseducationTuberculinlcsh:MedicineArticlemedical and nursing studentsYoung Adult03 medical and health sciences0302 clinical medicinelatent tb infectionLatent TuberculosisOccupational ExposureHealth carePrevalencequantiferon-tb testHumansMedicine030212 general & internal medicinemedical and nursing student0303 health sciencesLatent tuberculosisMediterranean Region030306 microbiologybusiness.industryRisk of infectionSettore MED/44 - Medicina Del LavoroRacial Groupslcsh:RPublic Health Environmental and Occupational HealthSkin testmedicine.diseasebacterial infections and mycosesmantoux skin testTest (assessment)Work exposureItalyInfectious disease (medical specialty)Family medicineoccupational biohazardFemaleStudents NursingbusinessInternational Journal of Environmental Research and Public Health
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