Search results for " Sleep Apnea"

showing 10 items of 173 documents

Behaviour of carbonyl groups in several clinical conditions: Analysis of our survey

2019

Protein carbonylation is a marker of oxidative protein damage, that is likely involved in the pathogenesis of several diseases. The aim of this study was to evaluate the protein carbonyl (PC) groups in different clinical conditions. It included different groups of subjects: 81 trained subjects; 23 subjects with mild essential hypertension; 31 middle-aged subjects with metabolic syndrome (MS); 106 subjects with MS not selected for age (subdivided into two subgroups, with and without diabetes mellitus); 91 obese adults subdivided in two subgroups (BMI 30-35 Kg/m2 and BMI > 35 kg/m2); 48 subjects with obstructive sleep apnea syndrome (OSAS) subdivided in accordance with the apnea/hypopnea i…

AdultMalemedicine.medical_specialtyOxidative stress arterial hypertension metabolic syndrome juvenile myocardial infarction chronic kidney failurePhysiologymedicine.medical_treatment030204 cardiovascular system & hematologyEssential hypertension030218 nuclear medicine & medical imagingProtein Carbonylation03 medical and health sciences0302 clinical medicineSurveys and QuestionnairesPhysiology (medical)Internal medicineDiabetes mellitusmedicineHumansDiseaseMyocardial infarctionDialysisbusiness.industryHematologymedicine.diseaseObstructive sleep apneaFemaleMetabolic syndromeCardiology and Cardiovascular MedicinebusinessOxidation-ReductionHypopneaBiomarkersKidney diseaseClinical Hemorheology and Microcirculation
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Multilevel temperature-controlled radiofrequency therapy of soft palate, base of tongue, and tonsils in adults with obstructive sleep apnea.

2003

Objectives/hypothesis The concept of two-level pharyngeal collapse in patients with obstructive sleep apnea is too simplified. Aggressive multilevel surgeries addressing several airway segments, including skeletal surgery, demonstrate improved success rates. Study design The study aimed to evaluate the safety and efficacy of multilevel radiofrequency application to soft palate, tonsils, and base of tongue in 16 white patients (mean age, 56.9 +/- 11.1 y; mean body mass index, 27.3 +/- 2.6 kg/m2) with obstructive sleep apnea. There was one dropout. Therapeutic effects after one treatment session were assessed 20.6 +/- 12.6 weeks postoperatively. Treatment outcome measurements were based on Ep…

AdultMalemedicine.medical_specialtyPolysomnographyPalatine TonsilPolysomnographyTongueTongueRespiratory disturbance indexmedicineHumansAgedSleep Apnea Obstructivemedicine.diagnostic_testSoft palatebusiness.industryEpworth Sleepiness ScaleSleep apneaMiddle Agedmedicine.diseaseSurgeryOtorhinolaryngologic Surgical ProceduresObstructive sleep apneamedicine.anatomical_structureTreatment OutcomeOtorhinolaryngologyAnesthesiaCatheter AblationFemalePalate SoftAirwaybusinessThe Laryngoscope
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The Apnea-Hypopnea Index Underestimates Systemic Inflammation in Women with Sleep-Disordered Breathing.

2018

Evidence suggests that sleep-related respiratory and related metabolic compromise may vary between females and males with sleep-disordered breathing (SDB). Our purpose was to elucidate possible gender differences in sleep-associated respiratory and inflammatory parameters in patients with SDB.A consecutive number of SDB patients (46 females and 167 males) who underwent polysomnography were retrospectively reviewed. Fibrinogen and C-reactive protein (CRP) concentration, apnea index (ApnI), hypopnea index (HypI), apnea-hypopnea index (AHI), average and minimal SpOApnI and AHI were significantly higher in males. Correlation analysis revealed striking gender differences: only in females, CRP co…

AdultMalemedicine.medical_specialtyPolysomnographyPolysomnography030204 cardiovascular system & hematologyBody Mass Index03 medical and health sciences0302 clinical medicineSleep Apnea SyndromesRisk FactorsInternal medicinemedicineHumansObesityAgedRetrospective StudiesInflammationSleep Apnea Obstructivebiologymedicine.diagnostic_testbusiness.industryC-reactive proteinSnoringApneaFibrinogenGeneral MedicineMiddle Agedmedicine.diseasenervous system diseasesrespiratory tract diseasesObstructive sleep apneaC-Reactive Protein030228 respiratory systemApnea–hypopnea indexCardiologyBreathingbiology.proteinFemalemedicine.symptombusinessHypopneaBody mass indexJournal of women's health (2002)
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Oral appliance therapy in obstructive sleep apnea: Long-term adherence and patients experiences.

2018

Background Despite the advances in the treatment of obstructive sleep apnea (OSA) with mandibular advancement appliances (MAA), their effectiveness is dependent on the patients’ compliance. Our aims were to evaluate the long-term adherence to MAA therapy and patients’ experiences of the treatment in OSA. Material and Methods Sixty-nine patients (52 males, 17 females; Mean age: 54.4±10.8 years) were included in the study. The subjects were mild (56%) and moderate (44%) OSA patients who had been treated using MAA at least 4 years prior to the study. A phone survey was used to determine the demographic characteristics of the patients, as well as to assess self-reported adherence to therapy, su…

AdultMalemedicine.medical_specialtyTime FactorsOral applianceDisease03 medical and health sciences0302 clinical medicinePatient satisfactionInternal medicinemedicineHumansGeneral DentistryIncome.statusAgedSleep Apnea Obstructivebusiness.industryResearchSleep apneaMiddle Agedmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Medically compromised patients in DentistryTemporomandibular jointObstructive sleep apneamedicine.anatomical_structure030228 respiratory systemOtorhinolaryngologyPatient SatisfactionUNESCO::CIENCIAS MÉDICASMarital statusPatient ComplianceSurgeryFemalebusinessMandibular Advancement030217 neurology & neurosurgeryMedicina oral, patologia oral y cirugia bucal
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Gender-specific anthropometric markers of adiposity, metabolic syndrome and visceral adiposity index (VAI) in patients with obstructive sleep apnea

2013

Obstructive sleep apnea often coexists with visceral adiposity and metabolic syndrome. In this study, we analysed gender-related differences in anthropometrics according to sleep apnea severity and metabolic abnormalities. In addition, the visceral adiposity index, a recently introduced marker of cardiometabolic risk, was analysed. Consecutive subjects with suspected obstructive sleep apnea (n = 528, 423 males, mean age ± standard deviation: 51.3 ± 12.8 years, body mass index: 31.0 ± 6.2 kg m(-2) ) were studied by full polysomnography (apnea-hypopnea index 43.4 ± 27.6 h(-1) ). Variables of general and visceral adiposity were measured (body mass index, neck, waist and hip circumferences, wai…

AdultMalemedicine.medical_specialtyWaistPolysomnographyCognitive NeuroscienceBlood PressurePolysomnographySettore MED/10 - Malattie Dell'Apparato Respiratorioreceiving-operator characteristic curveCardiovascular SystemBody Mass IndexBehavioral NeuroscienceInsulin resistanceInternal medicinemedicineHumansObesityAdiposityMetabolic SyndromeSex CharacteristicsSleep Apnea ObstructiveAnthropometrymedicine.diagnostic_testWaist-Hip Ratiobusiness.industryMetabolic Syndrome XSleep apneaGeneral MedicineSex CharacteristicMiddle Agedmedicine.diseaseObesityrespiratory tract diseasesObstructive sleep apneaEndocrinologyfat distributionBiological MarkerCardiologyFemalewomenWaist CircumferenceInsulin ResistanceMetabolic syndromebusinessBody mass indexBiomarkersHumanJournal of Sleep Research
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Associations of disordered sleep with body fat distribution, physical activity and diet among overweight middle-aged men

2015

This cross-sectional study aimed to investigate whether body fat distribution, physical activity levels and dietary intakes are associated with insomnia and/or obstructive sleep apnea among overweight middle-aged men. Participants were 211 Finnish men aged 30-65 years. Among the 163 overweight or obese participants, 40 had insomnia only, 23 had obstructive sleep apnea only, 24 had comorbid insomnia and obstructive sleep apnea and 76 were without sleep disorder. The remaining 48 participants had normal weight without sleep disorder. Fat mass, levels of physical activity and diet were assessed by dual-energy X-ray densitometry, physical activity questionnaire and 3-day food diary, respectivel…

AdultMalemedicine.medical_specialtyinsomniaCognitive Neurosciencephysical activityComorbidityMotor ActivityOverweightBody Mass IndexOSABehavioral NeuroscienceFolic AcidSleep Initiation and Maintenance DisordersSurveys and QuestionnairesInternal medicinemedicineInsomniaBody Fat DistributionHumansObesityExerciseFinlandAdiposityAgedSleep Apnea ObstructiveSleep disorderbusiness.industrySleep apneaApneata3141dietary intakesFeeding BehaviorGeneral MedicineMiddle AgedOverweightmedicine.diseaseDietary FatsObesityDietObstructive sleep apneaCross-Sectional Studiesfat distributionObesity AbdominalPhysical therapymedicine.symptombusinessBody mass indexJournal of Sleep Research
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Outcomes of uvulopalatopharyngoplasty with harmonic scalpel after failure of continuous positive airway pressure in sleep apnea syndrome.

2012

Our data highlight that uvulopalatopharyngoplasty (UPPP) with harmonic scalpel (HS) is a reliable treatment in selected patients affected by obstructive sleep apnea (OSA) and users of continuous positive airway pressure (CPAP).The aim of this paper was to verify the efficacy and applicability of UPPP with HS in the treatment of patients affected by OSA and users of CPAP.A total of 21 patients with a retropalatal obstruction and users of CPAP underwent UPPP with HS and were evaluated (before and 6 months after surgery) using the apnea/hypopnea index (AHI); oxygen desaturation index ≥4% (ODI(4)); Epworth Sleepiness Scale (ESS); snoring level (SL); subjective assessment of the postoperative pa…

AdultMalemedicine.medical_specialtymedicine.medical_treatmentPostoperative painstomatognathic systemUltrasonic Surgical ProceduresmedicineHumansContinuous positive airway pressureTreatment FailureOxygen desaturation indexAgedSleep Apnea ObstructiveEpworth Sleepiness Scale; Obstructive sleep apnea; Oxygen desaturation index; Postoperative painContinuous Positive Airway Pressurebusiness.industryEpworth Sleepiness ScaleUvulopalatopharyngoplastySleep apneaApneaGeneral MedicineMiddle Agedmedicine.diseaseEpworth Sleepiness ScaleObstructive sleep apneaapnea/hypopnea indexnervous system diseasesrespiratory tract diseasesSurgeryObstructive sleep apneaOtorhinolaryngologyApnea–hypopnea indexUvulaAnesthesiaObstructive sleep apnea; apnea/hypopnea index; oxygen desaturation index; Epworth Sleepiness Scale; postoperative painPharynxFemalemedicine.symptomPalate SoftbusinessHypopneaActa oto-laryngologica
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Clinical presentation of patients with suspected obstructive sleep apnea and self-reported physician-diagnosed asthma in the ESADA cohort.

2018

Obstructive sleep apnea (OSA) and asthma are often associated and several studies suggest a bidirectional relationship between asthma and OSA. This study analyzed the characteristics of patients with suspected OSA from the European Sleep Apnea Database according to presence/absence of physician-diagnosed asthma. Cross-sectional data in 16,236 patients (29.1% female) referred for suspected OSA were analyzed according to occurrence of physician-diagnosed asthma for anthropometrics, OSA severity and sleepiness. Sleep structure was assessed in patients studied by polysomnography (i.e. 48% of the sample). The prevalence of physician-diagnosed asthma in the entire cohort was 4.8% (7.9% in women, …

AdultMaleobesitymedicine.medical_specialtyCognitive NeurosciencePolysomnographyPopulationPolysomnographySettore MED/10 - Malattie Dell'Apparato Respiratoriota3111Cohort Studies03 medical and health sciencesBehavioral Neuroscience0302 clinical medicineobstructive sleep apnea ; asthma ; ESADA cohortInternal medicineEpidemiologygenderMedicineHumansProspective StudieseducationPhysician's RoleAsthmaAgededucation.field_of_studySleep Apnea Obstructivemedicine.diagnostic_testbusiness.industryta1184sleep-disordered breathingSleep apneaGeneral MedicineMiddle Agedmedicine.diseaseObesityAsthmarespiratory tract diseasesObstructive sleep apneaEuropeCross-Sectional Studies030228 respiratory systemCohortepidemiologyFemaleSelf Reportbusiness030217 neurology & neurosurgeryJournal of sleep research
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Unique sleep-stage transitions determined by obstructive sleep apnea severity, age and gender

2019

In obstructive sleep apnea, patients' sleep is fragmented leading to excessive daytime sleepiness and co-morbidities like arterial hypertension. However, traditional metrics are not always directly correlated with daytime sleepiness, and the association between traditional sleep quality metrics like sleep duration and arterial hypertension is still ambiguous. In a development cohort, we analysed hypnograms from mild (n = 213), moderate (n = 235) and severe (n = 277) obstructive sleep apnea patients as well as healthy controls (n = 105) from the European Sleep Apnea Database. We assessed sleep by the analysis of two-step transitions depending on obstructive sleep apnea severity and anthropom…

AdultMalesleep-disordered breathing.medicine.medical_specialtysleepdisordered breathing[SDV]Life Sciences [q-bio]Cognitive Neurosciencesleep dynamicsExcessive daytime sleepinessSettore MED/10 - Malattie Dell'Apparato Respiratorio600 Technik Medizin angewandte Wissenschaften::610 Medizin und Gesundheit::616 Krankheitenpower-law distribution03 medical and health sciencesBehavioral Neuroscience0302 clinical medicineInternal medicine616HumansMedicineexponential distributionsleep fragmentationStage (cooking)Retrospective StudiesSleep Apnea Obstructivebusiness.industryConfoundingsleep-disordered breathingAge FactorsGender IdentitySleep apneaGeneral MedicineMiddle AgedAnthropometrymedicine.diseaseSleep in non-human animals[SDV] Life Sciences [q-bio]Obstructive sleep apnea030228 respiratory systemsleep dynamicCohortCardiologyFemaleHuman medicinemedicine.symptomSleepbusiness030217 neurology & neurosurgery
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Breathe Right Nasal Strips and the Respiratory Disturbance Index in Sleep Related Breathing Disorders

1999

This investigation assesses the effects of Breathe Right nasal strips on the respiratory disturbance index (RDI) measured by polysomnography in patients suffering from obstructive sleep apnea and snoring. The positive effect of these strips on nasal ventilation was shown in earlier studies. Twenty-six patients with an RDI higher than 10 in an initial measurement underwent a second preoperative polysomnography with Breathe Right nasal strips in place. Nineteen of these 26 patients showed reduction of RDI during the second night of polysomnography using the nasal strips, indicating that nasal obstruction seems to be a predominant factor in the etiology of snoring and apnea in these individua…

AdultPolysomnographymedicine.medical_treatmentPolysomnographyNoseSeverity of Illness IndexBody Mass IndexOtolaryngology03 medical and health sciencesSleep Apnea Syndromes0302 clinical medicineAcoustic rhinometrySleep and breathingRespiratory disturbance indexmedicineHumans030223 otorhinolaryngologyAgedmedicine.diagnostic_testbusiness.industryRespirationSnoringUvulopalatopharyngoplastyApneaAcousticsMiddle Agedmedicine.diseaseDilatationObstructive sleep apneaOtorhinolaryngology030220 oncology & carcinogenesisAnesthesiaRhinomanometrymedicine.symptombusinessAmerican Journal of Rhinology
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