Search results for " Standard deviation"

showing 10 items of 79 documents

Target analysis of primary aromatic amines combined with a comprehensive screening of migrating substances in kitchen utensils by liquid chromatograp…

2015

An analytical strategy including both the quantitative target analysis of 8 regulated primary aromatic amines (PAAs), as well as a comprehensive post-run target screening of 77 migrating substances, was developed for nylon utensils, using liquid chromatography-orbitrap-high resolution mass spectrometry (LC-HRMS) operating in full scan mode. The accurate mass data were acquired with a resolving power of 50,000 FWHM (scan speed, 2 Hz), and by alternating two acquisition events, ESI+ with and without fragmentation. The target method was validated after statistical optimization of the main ionization and fragmentation parameters. The quantitative method presented appropriate performance to be u…

ChromatographyPrimary (chemistry)Food contactChemistryRelative standard deviationAnalytical chemistryTarget analysisFood ContaminationOrbitrapCooking and Eating UtensilsAnalytical Chemistrylaw.inventionMassNylonsKitchen utensilslawTandem Mass SpectrometryAnalytical strategyHumansAminesOrganic ChemicalsChromatography LiquidTalanta
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Mass spectrometry strategies for mycotoxins analysis in European beers

2013

In this work, an existent solid-phase extraction (SPE) procedure was used to study the occurrence of mycotoxins in different European beers. HPLC-QqQ-MS/MS and ultra high resolution mass analyser have been optimized for the analysis of 18 mycotoxins: the methods were validated according to the EU Commission Decision 2002/657/EC guidelines. In this sense, matrix-matched calibration was performed for each type of beer, obtaining an effective quantification. The recoveries ranged from 63 to 91% and repeatability and reproducibility expressed as relative standard deviation (RSD%) were lower than 17%. On one hand, HPLC-LTQ-Orbitrap ® was used for unambiguous identification of target mycotoxins, …

Ochratoxin ATriple quadrupoleChromatographyRelative standard deviationBeerRepeatabilityMycotoxinsMass spectrometryOrbitrapUltra high resolutionOrbitraplaw.inventionTriple quadrupole mass spectrometerchemistry.chemical_compoundchemistrylawSPEMycotoxinFood ScienceBiotechnology
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Evaluation of beauvericin and enniatins in Italian cereal products and multicereal food by liquid chromatography coupled to triple quadrupole mass sp…

2013

In this study, 48 multicereal baby foods samples including 25 of pasta and 23 of multicereal baby foods from supermarkets of Campania region (Italy) were analysed for evaluating the presence of beauvericin (BEA) and enniatins (ENs) A, A1, B, B1 and B4. Subsequently to evaluate the risk exposure of Italian population and infant population over the consumption of pasta or multicereal baby food, was, respectively, evaluated. For the above mentioned evaluation, a method developed in our laboratory by liquid chromatography tandem mass spectrometry was used. A liquid phase dispersion procedure was optimised for the simultaneous extraction of BEA and the five ENs from multicereal baby food samples…

PopulationRelative standard deviationFood Contamination01 natural sciencesmycotoxinAnalytical ChemistryBaby foodchemistry.chemical_compound0404 agricultural biotechnologyFusariumTandem Mass SpectrometryLiquid chromatography–mass spectrometryDepsipeptidesTriple quadrupole mass spectrometryFood scienceMycotoxineducationChromatography High Pressure Liquid2. Zero hungereducation.field_of_studyChromatography010401 analytical chemistryExtraction (chemistry)food and beveragesfood security04 agricultural and veterinary sciencesGeneral MedicineMycotoxins040401 food scienceBeauvericin0104 chemical sciences3. Good healthItalychemistryInfant FoodEdible GrainFood ScienceFood Chemistry
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Aerobic fitness mediates the intervention effects of a school-based physical activity intervention on academic performance. The school in Motion stud…

2021

Highlights • Physical activity is associated with increased aerobic fitness and academic performance. • Little is known on mechanism of physical activity effects on academic performance. • We performed a cluster randomized controlled trial. • Aerobic fitness mediated the intervention effect on academic performance. • Activity increasing aerobic fitness is a strategy to improve academic performance.

Mediation (statistics)medicine.medical_specialtyICC intra class correlationPhysical Therapy Sports Therapy and RehabilitationHealth InformaticsIntervention effectDisease clusterAcademic performanceAdolescentslaw.inventionRandomized controlled trialNumeracylawIntervention (counseling)medicineAerobic exerciseOrthopedics and Sports MedicinePAL Physically Active Learningbusiness.industryPhysical activityPublic Health Environmental and Occupational HealthRRegular ArticleCluster RCTScIM School in MotionVDP::Medisinske Fag: 700::Idrettsmedisinske fag: 850Test (assessment)DWBH Don’t worry – be HappyPhysical therapyAerobic fitnessMedicinebusinessSD standard deviation
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Monitoring of the smoking process by multicommutation Fourier Transform Infrared spectroscopy

2007

Abstract Nicotine was selected as the target molecule for monitoring of the smoking process by multicommutation Fourier Transform Infrared spectroscopy (FTIR). The method involved the use of CHCl3 for on-line extraction of nicotine from tobacco, cigarette filters and tobacco ash from NH4OH alkalinized samples, and absorbance measurement of the characteristic band at 1316 cm−1 in the stopped-flow mode, by obtaining the peak area in the range between 1334 and 1300 cm−1. Under the best operational conditions, the procedure developed provided a detection limit of 0.05 mg mL−1 nicotine, corresponding to 0.5 mg g−1 in the solid sample, a relative standard deviation less than 2.5%, and a sampling …

SmokePeak areaDetection limitNicotineChromatographyChemistrySmokingRelative standard deviationAnalytical chemistryInfrared spectroscopyBiochemistryFourier transform spectroscopyAnalytical ChemistryNicotineSpectroscopy Fourier Transform InfraredTobaccomedicineHumansEnvironmental ChemistryFourier transform infrared spectroscopyFiltrationSpectroscopyMonitoring Physiologicmedicine.drugAnalytica Chimica Acta
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Physicochemical compatibility and stability of nebulizable drug admixtures containing Dornase alfa and tobramycin.

2012

The objective of this in-vitro study was to determine whether admixtures of the inhalation solutions Pulmozyme(®) (Dornase alfa) and either Bramitob(®) or Tobi(®) (both containing Tobramycin) are physicochemically compatible and to analyze the aerodynamic parameters of these admixtures. After mixing, test solutions were stored at room temperature and under ambient light conditions over a period of 24 h. Tobramycin concentrations were determined by using a fluorescence immunoassay. Stability of dornase alfa was determined by size-exclusion high performance liquid chromatography, ultraviolet spectroscopy, sodium dodecyl sulfate polyacrylamide gel electrophoresis and tentacle strong cation-exc…

Pulmonary and Respiratory MedicineTime FactorsDrug StorageHigh-performance liquid chromatographyDrug Incompatibilitychemistry.chemical_compoundDrug StabilityAdministration InhalationmedicineTobramycinGeometric standard deviationDeoxyribonuclease IPharmacology (medical)Sodium dodecyl sulfateParticle SizeAerosolsChromatographyInhalationNebulizers and VaporizersBiochemistry (medical)Osmolar ConcentrationDornase alfaHydrogen-Ion ConcentrationRecombinant ProteinsAnti-Bacterial AgentsDrug CombinationsPharmaceutical SolutionschemistryCompatibility (mechanics)TobramycinFeasibility StudiesParticle fractionmedicine.drugPulmonary pharmacologytherapeutics
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Economic impact of mepolizumab in uncontrolled severe eosinophilic asthma, in real life

2021

Abstract Background and aims Severe asthma is burdened by frequent exacerbations and use of oral corticosteroids (OCS) which worsen patients’ health and increase healthcare spending. Aim of this study was to assess the clinical and economic effect of adding mepolizumab (MEP) for the treatment of these patients. Methods Patients >18 years old, referred to 8 asthma clinics, starting MEP between May 2017 and December 2018, were enrolled and followed-up for 12 months. Information in the 12 months before mepolizumab were collected retrospectively. The evaluation parameters included: OCS use, number of exacerbations/hospitalizations, concomitant therapies, comorbidity, and annual number of workin…

OR Odds RatioPediatricsSevere asthmaExacerbationAnti IL-5; Comorbidities; Mepolizumab; OCS; Pharmacoeconomics; Severe asthmagastroesophageal reflux diseaseSettore MED/10 - MALATTIE DELL'APPARATO RESPIRATORIOICS inhaled corticosteroidRate ratioOCS Oral Corticosteroidslaw.inventionComorbiditiesLAMA long acting muscarinic antagonist0302 clinical medicineRandomized controlled trialfractional nitric oxideInterquartile rangelawlong acting beta 2 agonistOdds RatioImmunology and AllergyRR Rate Ratio030223 otorhinolaryngologyPharmacoeconomicLOS Length of stayLOSIQRLAMAMEP MepolizumabORCISD Standard DeviationMEPPharmacoeconomicsACT Asthma Control TestComorbiditieCI Confidence Intervalsmedicine.druglcsh:Immunologic diseases. AllergyPulmonary and Respiratory Medicinemedicine.medical_specialtyinterquartile rangelong acting muscarinic antagonistImmunologyLABALABA long acting beta 2 agonistComorbidities Mepolizumab OCS Pharmacoeconomics Severe asthma Anti IL-5RRArticleRate Ratiochronic obstructive pulmonary disease03 medical and health sciencesPharmacoeconomicsOCS Oral CorticosteroidAsthma Control TestConfidence IntervalsFeNO fractional nitric oxideRCTs Randomized Controlled TrialmedicineCOPDGERD gastroesophageal reflux diseaseFeNOIQR interquartile rangeMepolizumabSDAsthmaRCTsOral Corticosteroidsbusiness.industryGERDmedicine.diseaseICS inhaled corticosteroidsACTComorbidityRandomized Controlled TrialsCI Confidence IntervalRCTs Randomized Controlled TrialsOCSCOPD chronic obstructive pulmonary disease030228 respiratory systemICSStandard DeviationLength of stayAnti IL-5inhaled corticosteroidslcsh:RC581-607businessMepolizumab
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Seawater carbonate chemistry and growth, physiological performance of the Manila clam Ruditapes philippinarum

2018

Ocean acidification may interfere with the calcifying physiology of marine bivalves. Therefore, understanding their capacity for acclimation and adaption to low pH over multiple generations is crucial to make predictions about the fate of this economically and ecologically important fauna in an acidifying ocean. Transgenerational exposure to an acidification scenario projected by the end of the century (i.e., pH 7.7) has been shown to confer resilience to juvenile offspring of the Manila clam, Ruditapes philippinarum. However, whether, and to what extent, this resilience can persist into adulthood are unknown and the mechanisms driving transgenerational acclimation remain poorly understood.…

Ocean Acidification International Coordination Centre (OA-ICC)TemperateRegistration number of speciesCondition indexSalinityBicarbonate ion standard deviationinorganicAlkalinity total standard deviationAlkalinityCalculated using seacarb after Orr et al. (2018)Growth rate standard deviationFugacity of carbon dioxide in seawater standard deviationExperimentTemperature waterCarbon inorganic dissolvedRuditapes philippinarumCalculated using seacarb after Nisumaa et al 2010PercentageAragonite saturation stateNorth PacificAlkalinity totalδ13C dissolved inorganic carbon standard deviationtotalpHRespirationTemperaturedissolvedLaboratory experimentCarbonate ionPartial pressure of carbon dioxide (water) at sea surface temperature (wet air)Carbon dioxide standard deviationTemperature water standard deviationContainers and aquaria 20 1000 L or 1 m 2δ13C dissolved inorganic carbonEarth System Researchδ13CContainers and aquaria (20-1000 L or &lt; 1 m**2)Metabolic rate of oxygen standard deviationstandard deviationUniform resource locator link to referenceCalcite saturation stateFugacity of carbon dioxide in seawaterwaterPartial pressure of carbon dioxideGrowth MorphologyContainers and aquaria (20-1000 L or < 1 m**2)Aragonite saturation state standard deviationBenthosUniform resource locator/link to referenceOther studied parameter or processSalinity standard deviationOcean Acidification International Coordination Centre OA ICCAnimaliaCarbon inorganic dissolved standard deviationCalcite saturation state standard deviationTypeBicarbonate ionCalculated using seacarb after Nisumaa et al. (2010)SpeciesGrowth rateCondition index standard deviationPartial pressure of carbon dioxide standard deviationMetabolic rate of oxygenCarbonate system computation flagpH standard deviationCarbonate ion standard deviationdissolved inorganic carbonCalculated using seacarb after Orr et al 2018Fugacity of carbon dioxide (water) at sea surface temperature (wet air)CarbonTreatmentPartial pressure of carbon dioxide water at sea surface temperature wet airCarbon dioxideMolluscaGrowth/MorphologySingle speciesFugacity of carbon dioxide water at sea surface temperature wet airBenthic animalsδ13C standard deviationCoast and continental shelf
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(Table 2) Age determination of sediment core NIOP-C2_929

2007

In this study we present a sea surface temperature (SST) record from the western Arabian Sea for the last 20,000 years. We produced centennial-scale d18O and Mg/Ca SST time series of core NIOP929 with focus on the glacial-interglacial transition. The western Arabian Sea is influenced by the seasonal NE and SW monsoon wind systems. Lowest SSTs occur during the SW monsoon season because of upwelling of cold water, and highest SSTs can be found in the low-productivity intermonsoon season. The Mg/Ca-based temperature record reflects the integrated SST of the SW and NE monsoon seasons. The results show a glacial-interglacial SST difference of ~2°C, which is corroborated by findings from other Ar…

Sample amountCalendar ageDepth top/minDEPTH sediment/rockAge 14C calibrated CALIB (Stuiver &amp; Reimer 1993)Age commentAge datedAge dated materialSize fractionTyroAge 14C calibrated CALIB (Stuiver & Reimer 1993)Age dated standard deviationDepth bottom/maxCoreAge 14C AMSNIOP-C2
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(Table 1) Age determination of sediment profile SO90-41KL/63KA

2002

The 14C ages of planktonic foraminifers Globigerinoides sacculifer bracketing the Younger Dryas in a d18O record of Globigerinoides ruber from a laminated sediment core on the Pakistani continental margin suggest that surface reservoir ages in the Arabian Sea were in excess of 1000 years during the deglaciation. A least squares error fit of a detailed 14C chronology to the (atmospheric) tree ring record gave variable early Holocene reservoir ages between 780 and 1120 years, well above the prebomb value of 640 years. Mid-Holocene reservoir ages are less well constrained but were probably closer to the prebomb value. The method used to fit individual core sections to the tree ring record was …

SO90SectionCalendar ageReservoir age standard errorAge 14C calibratedDEPTH sediment/rockAge commentAge dated materialAge datedSonneAge dated standard deviationReservoir ageAge 14C AMSComposite Core
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