Search results for " Stasi"

Intracapillary HbO2 Saturation in Tumor Tissue of DS-Carcinosarcoma During Normoxia

1978

Investigations on solid tumor tissue have shown that O2 uptake by cancer cells depends largely on the supply conditions. The absence of sufficient neovascularization and a general rarefaction of the terminal vascular bed during tumor growth as well as reduced and inhcmogeneous blood flew due to vascular stasis in neoplastic tissue prevent normal functions of the terminal vascular bed. In some areas of the tumor circulating blood is not visible despite the intactness of vessels. Stasis occurs since lacuna-like, sinusoidal and cystiform blood vessels cannot be drained completely because ‘tissue-pressure’ due to continuous cell proliferation can prevent efficient circulation. Thrombosis follow…

Der Einflu� einer ven�sen Stauung im Kopfbereich auf die Wasser- und Elektrolytausscheidung von Ratten

1960

1. Salt and water retention can be produced in rats by compression in the neck region or by ligature of the jugular veins.

Comparing diversity patterns in freshwater crustaceans from the Mediterranean area: emerging trends between morphological stasis and molecular evolut…

2013

Meine freie deutsche Jugend und Lagerfeuer: zwei grundverschiedene Erzähltexte über die DDR

2021

The article compares "Meine freie deutsche Jugend", 2003, of Claudia Rusch and "Lagerfeuer", 2003 of Julia Franck. These two texts are partly autobiographical and tell about the life of many young people in East Germany (DDR). The two authors write of traumatic experiences related to the political situation in the DDR which are still alive even today in united Germany in the memory of many Germans.

Alle radici dell'unità politica: polis, parola, conflitto

2016

The article tends to represent the power of the words in the greek polis, how the dialogue makes equal man to live in public space, and how this produces a seeming quiet only. On the other hand, Platon's perspective oulines a vertical power specifically with the aim to cancel every kind of conflict.

Hydrodynamic liver gene transfer mechanism involves transient sinusoidal blood stasis and massive hepatocyte endocytic vesicles

2005

The present study contributes to clarify the mechanism underlying the high efficacy of hepatocyte gene transfer mediated by hydrodynamic injection. Gene transfer experiments were performed employing the hAAT gene, and the efficacy and differential identification in mouse plasma of human transgene versus mouse gene was assessed by ELISA and proteomic procedures, respectively. By applying different experimental strategies such as cumulative dose-response efficacy, hemodynamic changes reflected by venous pressures, intravital microscopy, and morphological changes established by transmission electron microscopy, we found that: (a) cumulative multiple doses of transgene by hydrodynamic injection…

COVID ‐19, thromboembolic risk, and Virchow's triad: Lesson from the past

2020

Abstract COronavirus Infectious Disease which started in 2019 (COVID‐19) usually presents with the signs and symptoms of pneumonia. However, a growing number of recent reports highlight the fact that the infection may be by far more than only a respiratory disease. There is evidence of an increased thromboembolic risk in COVID‐19 patients, with a variety of manifestations in terms of ischemic stroke, deep vein thrombosis, acute pulmonary embolism, acute myocardial infarction, systemic arterial embolism, and placental thrombosis. The German physician Rudolph Virchow, about two centuries ago, described three pivotal factors contributing together to thromboembolic risk: endothelial injury, hyp…

Does aspirin save lives in patients with COVID-19?

2021

‘An aspirin a day keeps the heart attack away’, is this also true in the prevention of thrombotic events associated with COVID-19? The rising COVID-19 pandemic has led to much work in the understanding of the pathophysiology of the disease. COVID-19 infection is thought to be an endothelial disease. Supporting this concept, it has been suggested that infection with SARS-CoV-2, the aetiological agent for COVID-19 infection, leads to a state mimicking Virchow’s triad, that is, vascular endothelial injury, blood stasis and clotting in concert with systemic inflammation resulting in systemic thrombosis. In keeping with this concept, moderately and critically ill patients with COVID-19 have been…

Lower extremity soft tissue defect reconstruction with the serratus anterior flap

2013

Reconstruction of limb-threatening lower extremity defects presents unique challenges. The selected method must provide adequate coverage of exposed bone, joints, and tendons while maximizing function of the limb. The traditional workhorse flaps, the free latissimus dorsi and rectus abdominis flaps, have been associated with donor site morbidity and bulkiness that can impair rehabilitation. We report a case series (n = 18) in which the free serratus anterior muscle flap and split thickness skin graft (STSG) was used for lower limb soft tissue coverage. Injuries were due to diabetes (9/18), trauma (7/18), and chronic venous stasis (2/18). A 94% flap survival rate was observed and all but one…