Search results for " Stimulus"
showing 10 items of 75 documents
Chapter 1 Pain and hyperalgesia: definitions and theories
2006
Publisher Summary This chapter describes pain as an unpleasant sensory and emotional experience associated with actual or potential tissue damage. It reflects the first-person perspective of pain: “pain is an unpleasant sensory and emotional experience.” “Nociception” is a term that may more adequately reflect these aspects of pain sensation. The chapter reviews that the adequate stimulus to activate the receptive organs of the nociceptive system consists of either actual or potential tissue damage. But not all noxious stimuli are detected by the nociceptive system. Therefore, the adequate stimulus for this system in the strict sense is that subset of noxious stimuli that can be encoded by …
Antioxidant and anti-inflammatory properties of plants extract
2019
Inflammation is an adaptive response triggered by noxious stimuli and conditions such as infection and tissue injury [...]
Fiscal Adjustment and Business Cycle Synchronization
2013
Using a panel of annual data for 20 countries we show that synchronized fiscal consolidation (stimulus) programmes in different countries make their business cycles more closely linked, especially in the case of fiscal adjustments lasting 2 or 3 years. We also find: (i) little evidence of decoupling when an inflation targeting regime is unilaterally adopted; (ii) an increase in business cycle synchronization when countries fix their exchange rates and become members of a monetary union; (iii) a positive effect of bilateral trade on the synchronization of business cycles.
Interpositus nucleus inactivation reduces unconditioned response amplitude after paired but not explicitly unpaired treatment in rabbit eyeblink cond…
2001
The amplitude of unconditioned responses (URs) in unconditioned stimulus (US) alone presentations were measured in six rabbits during explicitly unpaired and classical conditioning treatments. After both phases of the experiment, the interpositus nucleus (IPN) was reversibly inactivated by a cold probe. URs after unpaired treatment were unaffected by inactivation but after acquisition of a robust level of conditioned responses (CRs), URs in US-alone test trials were reduced in amplitude compared with URs immediately before and after inactivation. The results suggest that the IPN has a role in CR-related reflex modification.
Influence of Musical Expertise on the processing of Musical Features in a Naturalistic Setting
2019
Musical training causes structural and functional changes in the brain due to its sensory-motor demands, but the modulatory effect of musical training on music feature processing in the brain in a continuous music listening paradigm, has not been investigated thus far. In this work, we investigate the differences between musicians and non-musicians in the encoding of musical features encompassing musical timbre, rhythm and tone. 18 musicians and 18 non-musicians were scanned using fMRI while listening to 3 varied stimuli. Acoustic features corresponding to timbre, rhythm and tone were computationally extracted from the stimuli and correlated with brain responses, followed by t-tests on grou…
Sex pheromones are not always attractive: changes induced by learning and illness in mice
2014
A male-specific major urinary protein named darcin is attractive to female mice, Mus musculus, stimulates a learned attraction to volatile components of a male's urinary odour and induces spatial learning. In this article we show that darcin also induces learned attraction for a previously neutral olfactory stimulus (the odorant isoamyl acetate), acquired by repeated presentation of both stimuli together. We hypothesize that this is a case of olfactory–vomeronasal associative learning, in which darcin acts as the unconditioned reinforcer. However, the presence of darcin is not always attractive to adult female mice. Urine from males parasitized by the nematode Aspiculuris tetraptera has no …
The Adequate Stimulus
2008
The term adequate stimulus describes that class of environmental phenomena that requires the least amount of energy to elicit a percept mediated by a particular sensory system, implying that the receptive organs of that sensory system are specialized to detect those phenomena. It was difficult to transfer this concept to the perception of pain and to the nociceptive system. Many different stimuli may cause pain (pin prick, burn injury, freeze injury, inflammation, etc.), none of which needs particularly low amounts of energy. The common denominator of those stimuli is that they threaten to cause tissue damage (in Greek: νoξη Noxe). Hence the adequate stimulus to elicit pain is traditionally…
Effectiveness of Self-Hypnosis on the Relief of Experimental Dental Pain: A Randomized Trial.
2016
This randomized, controlled clinical trial evaluates the effectiveness of self-hypnosis on pain perception. Pain thresholds were measured, and a targeted, standardized pain stimulus was created by electrical stimulation of the dental pulp of an upper anterior tooth. Pain stimulus was rated by a visual analogue scale (VAS). The pain threshold under self-hypnosis was higher (57.1 ± 17.1) than without hypnotic intervention (39.5 ± 11.8) (p < .001). Pain was rated lower on the VAS with self-hypnosis (4.0 ± 3.8) than in the basal condition without self-hypnosis (7.1 ± 2.7) (p < .001). Self-hypnosis can be used in clinical practice as an adjunct to the gold standard of local anesthesia for pain m…
Hilbert-Huang versus Morlet wavelet transformation on mismatch negativity of children in uninterrupted sound paradigm
2008
Background Compared to the waveform or spectrum analysis of event-related potentials (ERPs), time-frequency representation (TFR) has the advantage of revealing the ERPs time and frequency domain information simultaneously. As the human brain could be modeled as a complicated nonlinear system, it is interesting from the view of psychological knowledge to study the performance of the nonlinear and linear time-frequency representation methods for ERP research. In this study Hilbert-Huang transformation (HHT) and Morlet wavelet transformation (MWT) were performed on mismatch negativity (MMN) of children. Participants were 102 children aged 8–16 years. MMN was elicited in a passive oddball parad…
Is pain sensitivity altered in people with Alzheimer's disease? A systematic review and meta-analysis of experimental pain research
2016
Background Clinical studies suggest people with Alzheimer's disease (AD) have altered pain sensitivity. Experimental pain research is equivocal. Objective Conduct a meta-analysis to investigate if people with AD have altered pain sensitivity compared to healthy controls (HCs). Methods Three authors searched electronic databases from inception till November 2015 for experimental pain studies in AD vs. HCs. Outcome measures were pain threshold, tolerance, pain ratings, heart rate response to noxious stimuli and the Facial Action Coding System (FACS). Random effect meta-analysis calculating Hedges' g ± 95% confidence intervals (CI) was conducted. Results Thirteen studies were identified, inclu…