Search results for " Strategy"
showing 10 items of 764 documents
MLOG: a strongly typed confluent functional language with logical variables
1994
Poirriez, V., MLOG: a strongly typed confluent functional language with logical variables, Theoretical Computer Science 122 (1994) 201-223. A new programming language called MLOG is introduced. MLOG is a conservative extension of ML with logical variables. To validate our concepts, a compiler named CAML Light FLU0 was implemented. Numerous examples are presented to illustrate the possibilities of MLOG. The pattern matching of ML is kept for X-calculus bindings and an unification primitive is introduced for the logical variables bindings. A suspension mechanism allows cohabitation of pattern-matching and logical variables, Although the evaluation strategy for the application is fixed, the or…
Interest of exome sequencing trio-like strategy based on pooled parental DNA for diagnosis and translational research in rare diseases.
2021
Abstract Background Exome sequencing (ES) has become the most powerful and cost‐effective molecular tool for deciphering rare diseases with a diagnostic yield approaching 30%–40% in solo‐ES and 50% in trio‐ES. We applied an innovative parental DNA pooling method to reduce the parental sequencing cost while maintaining the diagnostic yield of trio‐ES. Methods We pooled six (Agilent‐CRE‐v2–100X) or five parental DNA (TWIST‐HCE–70X) aiming to detect allelic balance around 8–10% for heterozygous status. The strategies were applied as second‐tier (74 individuals after negative solo‐ES) and first‐tier approaches (324 individuals without previous ES). Results The allelic balance of parental‐pool v…
Relocating within the university : proposal of a relocation rate based on a study of educational trajectories
2017
La universidad ha vivido transformaciones importantes en los últimos años como es la expansión de una mayor heterogeneidad en el perfil de los estudiantes. Esta realidad ha implicado cambios significativos en el acceso a la universidad, los resultados y la salida hacia el mercado laboral de los universitarios. Los estudiantes provienen de entornos socioeconómicos diferentes, de vías de acceso diversas y se incorporan a la universidad con distintas expectativas y ritmos están produciendo una diversificación de las trayectorias educativas. En este sentido, esta diversificación conduce a una mayor frecuencia de trayectorias que desencadenan cambios de grado y abandonos de los estudios, lo que …
Seabirds mated for life migrate separately to the same places: behavioural coordination or shared proximate causes?
2015
Long-term pair bonds occur in diverse animal taxa, but they are most common in birds, and can last from a few years to a lifetime. In many of these species, after the reproductive season, birds migrate to distant nonbreeding grounds where they remain for several months, and until recently, little was known about whether partners maintain contact during migration. This gap in knowledge was primarily due to past methodological difficulties in tracking long-term, large-scale movements of individuals. However, the development of new animal-borne geolocation devices has enabled researchers to track movements of individuals for a year or more. We tracked the annual migrations of both members of b…
The new role of the corporate and functional strategies in the tourism sector: Spanish small and medium-sized hotels
2005
This article aims at establishing the presence or lack of possible relationships between the existence of a logical global strategy definition in Spanish small and medium-sized hotels and its links with functional or department strategies involving four areas – marketing, technology, human resources and finance. Results show that there is a relationship between enterprise size – using business turnover as a yardstick – and the proper definition of technology, human resources and finance functions. There is also a relationship between enterprise size, determined by the number of employees, and an adequate definition of corporate strategy and technology and human resources department function…
FACTORS AFFECTING CHINESE HAMSTER OVARY CELL PROLIFERATION AND VIABILITY
2019
Advantageous cultivation procedures for the Chinese hamster ovary (CHO) cells are necessary for the productive commercial production of biopharmaceuticals. A main challenge that needs to be addressed during the process development is the differences in each cell line requirements concerning the nutrients and feed strategies in order to achieve the desired growth characteristics. Therefore, within the current research, a naïve high cell density serum free suspension adapted CHO cell line was tested with glucose and glutamine rich feeds in fed-batch Erlenmeyer shake flask cultures. Glucose consumption rate was adjusted to develop the optimal feed strategies. Obtained results indicated that hi…
Which Are Convenient Instruments to Reduce Bad Governance and Social Disparities in Least Developed Countries? (Welche Instrumente sind geeignet, 'Ba…
2008
This paper analyses the relationship between Bad Governance and social disparities in Least Developed Countries. Then it gives an overview on the common set of mesures used to improve gouvernance structures. Concluding, advantages and problems of these mesures are discussed and a perspective is given on the Good Governance debate.
La Fuerza Multilateral y la multiplicidad nuclear en la OTAN (1960-1965)
2017
Desde finales de la década de 1950 y hasta 1965, el gobierno de Estados Unidos (EEUU) promovió la creación de una fuerza naval armada con misiles balísticos, conocida como Fuerza Multilateral (Multilateral Force, MLF), con tripulaciones multinacionales y bajo mando de la Organización del Tratado del Atlántico Norte (OTAN). La propuesta inicial de la administración Eisenhower trataba de satisfacer las quejas de algunos miembros de la OTAN acerca del monopolio que EEUU ejercía sobre la defensa nuclear de Europa. Aunque oficialmente se buscaba proporcionar un papel activo a los países europeos, en particular Alemania, en la estrategia nuclear conjunta, con la MLF los EEUU confiaban en inducir …
Somatisierung - Konversion - Dissoziation: Verhaltenstherapeutische Therapiestrategien/ Somatization – Conversion – Dissociation: Strategies of Behav…
2005
Zusammenfassung Die modernen verhaltenstherapeutischen Ansatze zur Behandlung von Patienten mit unklaren korperlichen Symptomen haben sich auf der Grundlage der Klassifikationssysteme DSM-IV und ICD-10 entwickelt. Dort sind die somatoformen Storungen als einheitliche Storungsgruppe definiert. Erganzend zur deskriptiven Diagnostik hat die Verhaltenstherapie ein Storungsmodell entwickelt, welches atiologische, auslosende und aufrecht erhaltende Faktoren im Sinne eines Regelkreismodells beschreibt. Die therapeutischen Ziele und Strategien konnen konsequent aus diesem Modell abgeleitet werden. Zentrale Komponenten sind (1) die Motivierung des Patienten fur ein psychotherapeutisches Vorgehen, (2…
THE ROLE OF ACCOUNTABILITY WITHIN A ZERO WASTE STRATEGY: EVIDENCES FROM A SICILIAN SMALL MUNICIPALITY
2017
Building a sustainable city model comprising an integrated waste management system has become an indispensable choice, also in the light of increasingly stringent regulatory constraints. The core point of the paper is the implementation of a zero waste strategy in a small municipality in Sicily. Given that only the unceasing participation of citizens may ensure the persistence over time of such a policy, accountability process works letting citizens approach directly the end-results of their ongoing good practices. By building up a SD model framed by a DPM chart, it is possible to figure out how disclosure of public saving resulting from the decreasing amount of waste piled up in the landfi…