Search results for " Stratification."

Prognostic impact of copeptin in pulmonary embolism: a multicentre validation study.

2018

To externally validate the prognostic impact of copeptin, either alone or integrated in risk stratification models, in pulmonary embolism (PE), we performed a post hoc analysis of 843 normotensive PE patients prospectively included in three European cohorts.Within the first 30 days, 21 patients (2.5%, 95% CI 1.5–3.8) had an adverse outcome and 12 (1.4%, 95% CI 0.7–2.5) died due to PE. Patients with copeptin ≥24 pmol·L−1 had a 6.3-fold increased risk for an adverse outcome (95% CI 2.6–15.5, p<0.001) and a 7.6-fold increased risk for PE-related death (95% CI 2.3–25.6, p=0.001). Risk classification according to the 2014 European Society of Cardiology (ESC) guideline algorithm identified 248…

Prognostic Value of Troponins in Patients With or Without Coronary Heart Disease: Is it Dependent on Structure and Biology?

2020

Convincing evidence has emerged that cardiac troponins (cTns) T and I are the biochemical gold standard for diagnosing cardiac injury, and may also be used as efficient screening and risk stratification tools, especially when measured with the new high-sensitivity (hs-) immunoassays. In this narrative review, we aim to explore and critically discuss the results of recent epidemiological studies that have attempted to characterise the prognostic value of cTns in patients with or without cardiovascular disease, and then interpret this information according to cTn biology. Overall, all recent studies agree that higher blood levels of cTns reflect the larger risk of cardiovascular events and/or…

From limit to centrality. Regeneration of the Genoa's port area through architectural and urban design

2012

This survey’s core is the case study of the regeneration of the port area and of the urban waterfront of the city of Genoa, as an emblematic example where the architectural and urban design plays an important role, oriented to the transformation of the port area and to the modification of the relationship that exists between the harbour and the city. In particular this will deepen the possibility, to reverse the condition of limit that characterizes the port area into a new centrality, through the design, passing by intermediate steps that redefine the modalities of access and of connection between city and port, breaking the condition of isolation that ports usually present. As a matter of…

Controversial issues in soft tissue solitary fibrous tumors: A pathological and molecular review

2019

The clinical evolution of solitary fibrous tumor (SFT) remains unclear. Although various clinical, morphological and molecular criteria may indicate increased risk of malignancy, some SFT can still progress despite having a clearly benign appearance. Various risk stratification systems have been proposed, but unfortunately they are not sufficient to precisely determine the malignant potential. In this review, we discuss current knowledge on SFT, focusing on the following controversial issues: (i) the diverse morphologic spectrum: 'the great simulator;' (ii) malignant transformation or dedifferentiation; (iii) current risk stratification systems; and (iv) molecular factors associated with cl…

Risk stratification for invasive fungal infections in patients with hematological malignancies: SEIFEM recommendations

2016

Invasive fungal infections (IFIs) are an important cause of morbidity and mortality in immunocompromised patients. Patients with hematological malignancies undergoing conventional chemotherapy, autologous or allogeneic hematopoietic stem cell transplantation are considered at high risk, and Aspergillus spp. represents the most frequently isolated micro-organisms. In the last years, attention has also been focused on other rare molds (e.g., Zygomycetes, Fusarium spp.) responsible for devastating clinical manifestations. The extensive use of antifungal prophylaxis has reduced the infections from yeasts (e.g., candidemia) even though they are still associated with high mortality rates. This pa…

Laghi Artificiali dell'Italia meridionale e delle isole maggiori

2014

In questo articolo gli autori analizzano i principali fattori ecologici che determinano il funzionamento dei laghi artificiali localizzati nel meridione d’Italia e nelle isole maggiori. In particolare, viene illustrato come il ciclo idrologico annuale di questi ecosistemi sia fortemente influenzato dalle attività umane connesse all’uso dell’acqua invasata. Tali attività spesso interferiscono negativamente con la dinamica dei fattori fisici (stratificazione/circolazione), chimici (concentrazioni di nutrienti e ossigeno) e biologici (successione stagionale del fitoplancton) che governano il funzionamento di questi ecosistemi. Comprendere come il cambiamento climatico in atto influenzi il cicl…

Heterogeneous vertical structure of the bacterioplankton community in a non-stratified Antarctic lake

2013

10 páginas, 4 figuras, 2 tablas.

2015

Does being from a higher social class lead a person to engage in more or less prosocial behavior? Psychological research has recently provided support for a negative effect of social class on prosocial behavior. However, research outside the field of psychology has mainly found evidence for positive or u-shaped relations. In the present research, we therefore thoroughly examined the effect of social class on prosocial behavior. Moreover, we analyzed whether this effect was moderated by the kind of observed prosocial behavior, the observed country, and the measure of social class. Across eight studies with large and representative international samples, we predominantly found positive effect…

Social Inequalities in French Secondary Schools : From Figures to Theories

1996

In spite of the unified type of junior secondary school (the "college") implemented in France since 1975, significant social inequalities of school careers can be observed today. A specific longitudinal study sheds some light on the variety of mechanisms which generate these social inequalities. Difference in academic progress is one mechanism, but parents' strategies are also important. Finally, another aspect of social inequality arises from the school attended, some schools being more selective at the streaming points, these "school effects' being related to the social characteristics of the pupils of the catchment area. All these facts and figures have some relevance with regard to diff…

From rural studies to the analysis of localized social spaces

2014

Urban society seems to have penetrated every corner of France, reducing the object of rural sociology and ethnology to nothing. These disciplines are built on a sharp rural/urban split, reserving the canonical vocabulary of sociology, such as the analysis of social class, for urban settings. Rural studies were founded on an ad hoc conceptualization borrowed from anthropology (peasant society, community, village collectivity, village interconnaissance or everyone knowing each other, notables). The radical development of contemporary rural worlds has swept this conception away. But are today’s contemporary rural worlds the exact equivalents of urban worlds? In this paper we defend the idea th…