Search results for " Structural"
showing 10 items of 1751 documents
Construction sequence analysis of long-span cable-stayed bridges
2018
Abstract In cantilever construction of long-span cable-stayed bridges the stressing sequence of stays is fundamental for establishing the final configuration of the bridge. The structural behaviour of these bridges is usually evaluated through a forward staged construction analysis, in which the values of the prestressing forces to be applied to stays are the main unknowns. A unified procedure for determining the initial cable forces and for analyzing the entire sequence is presented here, considering the geometric nonlinearity of stays through the Dischinger equivalent elastic modulus. The target is the simultaneous determination of the initial cable forces with the simulation of the const…
Structural change in a Ricardian world economy: The role of extensive rent
2019
Abstract We study an implication of the Ricardian theory of differential extensive rent in a free trade regime. To this effect we develop a Ricardian two country two commodity open economy model. We assume that, unlike labour, land is heterogeneous both within and across countries and that the ratio of high to low quality land is different among the trading countries. By means of a numerical example we show that as the process of worldwide capital accumulation (and population growth) proceeds an industrial country may find it convenient to increase its domestic corn production and even reverse completely the pattern of its imports and exports.
A novel thermoeconomic analysis under dynamic operating conditions for space heating and cooling systems
2019
Abstract Thermoeconomic analysis allows for a deep understanding of the cost formation process within an energy system, providing insights into the possible routes for improvement. Several thermoeconomic approaches are well-established for application in systems with steady operating conditions, such as power plants, while a limited number of applications to air-conditioning systems in buildings have been proposed, due to the difficulties in dealing with very irregular load profiles and unsteady plant operating conditions. This study investigates the potential of Thermoeconomics as a support for decision making in building energy systems, proving its capability to identify trade-offs betwee…
Experimental investigation on the compressive behavior of short-term preloaded carbon fiber reinforced polymer-confined concrete columns
2017
Strengthening of concrete columns with fiber reinforced polymer sheets provides a good improvement to the existing structural members in terms of load and strain capacity due to the properties of the composite jacket. A proper knowledge of the load–strain response of the composite members is necessary to design retrofitting intervention of existing structures; however, so far the available design methods do not allow to take into account the effect of the possible presence of service loads on the compressive behavior of the reinforced columns. An experimental investigation on the compressive behavior of preloaded circular concrete columns reinforced with carbon fiber reinforced polymer was …
A bioactive designer cytokine for human hematopoietic progenitor cell expansion
1997
Efficient expansion of hematopoietic progenitor cells requires, at least, the simultaneous stimulation of the receptors c-kit and gp130. While c-kit is activated by SCF; gp130, in cells which do not express sufficient amounts of IL-6R, can be activated by the complex of soluble IL-6R (sIL-6R) and IL-6. The therapeutic use of IL-6/sIL-6R, however, has been hampered by the high concentrations of the sIL-6R protein required. We have designed a fusion protein of sIL-6R and IL-6, linked by a flexible peptide chain, that was expressed to high levels. On gp130 expressing cells the fusion protein turned out to be fully active at 100 to 1,000-fold lower concentration than the combination of unlinked…
Modulating carbohydrate-based hydrogels as viscoelastic lubricant substitute for articular cartilages
2017
Viscosupplementation is a therapeutic approach for osteoarthritis treatment, where the synovial fluid, the natural lubricant of the joints, is replaced by viscoelastic solutions with rheological properties comparable or better than the starting material. This study presents the development of an innovative platform for viscosupplementation, based on the optimization of polysaccharide-based colloidal hydrogel, aiming to reduce on-site enzyme degradation and enhance the possibility of hyaluronic acid substitution with alternative biomaterials. Catanionic vesicles are proposed as physical crosslinker that can guarantee the formation of a 'soft', tunable network, offering a dual-therapeutic app…
Cahiers d'anthropologie sociale (7), Desastres
2011
Cell-Free Coelomic Fluid Extracts of the Sea Urchin Arbacia lixula Impair Mitochondrial Potential and Cell Cycle Distribution and Stimulate Reactive …
2020
Triple-negative breast cancer (TNBC) is a highly malignant tumor histotype which lacks effective targeted therapies, thereby being considered as the most aggressive form of breast carcinoma. To identify novel compounds which could counteract TNBC cell growth, we explored the in vitro effects of crude extracts and <
Does phosphorus affect the industrial Portland cement reactivity?
2018
Abstract The effect of phosphorous on the mineralogy and reactivity of Portland cement has been investigated through an industrial clinkers series. The samples were collected from the same Tunisian cement plant and classified according to the content of P2O5 from 0.5% to 1.1%. All samples were manufactured at the same thermal and cooling conditions as well as possible. The specimens were characterized by X-ray fluorescence spectrometry and optical microscopy techniques and their mineralogy was determined by X-ray powder diffraction coupled to the Rietveld analysis. The cements reactivity prepared from the clinkers was followed by means of isothermalcalorimetry. The compressive strength of t…
Pumice powder as filler of self-compacting concrete
2015
Abstract An experimental study on the rheological and mechanical properties of self-compacting concrete with pumice powder used as filler additive is presented. Self-compacting concrete (SCC) shows its peculiar characteristics in the fresh state and many researches have been developed with reference to its rheological characteristics paying attention to the techniques of self-compacting properties assessment. One of the most important aspect in concrete mix-design is the type and the amount of fillers with respect to water and cement: this amount has great influence not only on self-compacting properties (fluidity, segregation, etc.), but also on the mechanical properties of the mixture. Vo…