Search results for " Study"
showing 10 items of 9094 documents
Common variants at VRK2 and TCF4 conferring risk of schizophrenia
2011
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field. Common sequence variants have recently joined rare structural polymorphisms as genetic factors with strong evidence for association with schizophrenia. Here we extend our previous genome-wide association study and meta-analysis (totalling 7 946 cases and 19 036 controls) by examining an expanded set of variants using an enlarged follow-up sample (up to 10 260 cases and 23 500 controls). In addition to previously reported alleles in the major histocompatibility complex region, near neurogranin (NRGN) and in an intron of transcription factor 4 (TCF4), we find two novel variants show…
Inclusion at the time of school-work alternance: new challenges and perspectives for connection between school, formation and world of job
2019
The historical moment that we are experiencing is characterized by several technological changes as well as by demographic ones. So, the world of work is even more flexible and in continuous evolution. It follows that it’s increasingly present the need to promote an authentic knowledge that can combine theory and practice, knowledges and abilities with the aim to develop competences. So, school becomes the educative agency that has to combine formative needs of individual with competences required by the job market, with the purpose of offering equal opportunities to all its students; this is the perspective offered by Capability Approach, whose declination in a scholastic context can allow…
Latvian or English – the Language Situation in Scientific Communication in Latvia
2020
The growing dominance of English as an international language of scientific communication in the world has been widely acknowledged. However, its effect in the relevant discourse community in Latvia is still to be explored. A case study was undertaken to improve upon the current understanding of the choice of scientific publishing language in Latvia and explore historical factors underpinning the current predominance of English as the lingua franca of the scientific community. It has been concluded that with a strong focus on international publishing in indexed databases, the role of English in scientific communication in Latvia has an increasing tendency to grow. Although currently English…
Are Public Subsidies to Encourage Young Farmers Effective? Case Study of a First-Time Farm Set Up by a Young Female Farmer in the Valencian Region of…
2021
Generational renewal and the incorporation of women into the rural world are fundamental for the sustainability and modernisation of the agricultural sector. Hence the special government protection granted to the sector, which appears in both European legislation on rural issues and in the global strategy of the 2030 Agenda and the Sustainable Rural Development Goals involving a commitment to measures aimed at helping young farmers to set up agricultural holdings and especially at encouraging women to engage in farm management. In the case of Spain, this is nothing new, given that Law 35/2011 on the Shared Ownership of Agricultural Holdings became a veritable revolution in terms of gender i…
Student engagement, truancy, and cynicism : a longitudinal study from primary school to upper secondary education
2021
Truancy in upper secondary education is a widespread problem, which contributes significantly to school dropout risk. However, the underlying mechanisms of truancy have remained unstudied. This longitudinal study of 1853 Finnish students examined how initial levels and changes in student engagement from primary (Grade 6) to lower secondary school (Grades 7 and 9) predicted truancy in upper secondary education, and whether cynicism (losing interest in school) mediated the relationship between engagement and truancy. Growth curve models showed that high engagement levels in primary school and increases in engagement over time predicted less truancy in upper secondary education. Cynicism media…
Kritisku gadījumu analīze 11. klases skolēnu pašrefleksijas prasmju attīstībā angļu valodas stundās
2016
Darba mērķis ir izpētīt, kā kritisku gadījumu analīze ir izmantojuma 11. klases angļu valodas (kā svešvalodas) stundās, lai veicinātu skolēnu pašrefleksijas prasmes. Pētījumā piedalījās divdesmit divi 11. Klases skolēni un viens skolotājs. Pētījums noformēts kā skolotāja portfolio. Darba praktiskā daļa pamatota ar teorētiskiem pētījumiem. Pētījumā nepieciešamie dati iegūti, veicot skolēnu aptaujas, individuālās un grupu intervijas, skolēnu pašrefleksijas žurnālu un analizējot skolēnu rakstiska atsauksmes. Lai attīstītu skolēnu pašrefleksijas prasmes un nosacījuma palīgteikumu (conditional phrases) lietojumu, pētījumā tika izmantota Flanagana (Flannagan, 1954) un Tripa (Tripp, 1993) attīstīt…
From Country Girl in Southern Finland to Longitudinal Research into Alternatives to Aggression and Violence
2021
Lea Pulkkinen, born in Finland in 1939, is Emerita Professor of Psychology at the University of Jyväskylä (Finland). She is best known for creating the ongoing Jyväskylä Longitudinal Study of Personality and Social Development (JLSPSD). The study was specifically intended to test the hypothesis that the human brain allows for more variation in behavior than the simple ‘fight or flight’ response observed in animal studies of aggression. She further hypothesized that humans’ capacity for cognitive control over emotional behavior was the key factor involved in controlling aggressive behavior. These hypotheses led her to devise an impulse control model to depict behavioral alternatives, which s…
Real-world experience with dupilumab in severe asthma: One-year data from an italian named patient program
2021
Raffaele Campisi,1 Claudia Crimi,1 Santi Nolasco,2 Bianca Beghè,3 Leonardo Antonicelli,4 Gabriella Guarnieri,5 Nicola Scichilone,6 Morena Porto,2 Luigi Macchia,7 Giulia Scioscia,8 Maria Pia Foschino Barbaro,8 Alberto Papi,9 Nunzio Crimi1,2 1Respiratory Medicine Unit, A.O.U. Policlinico “G. Rodolico -San Marco”, Catania, Italy; 2Department of Clinical and Experimental Medicine, Section of Respiratory Diseases, University of Catania, Catania, Italy; 3Respiratory Medicine Unit, Department of Medicine, University of Modena and Reggio Emilia, Modena, Italy; 4Allergy Unit, Department of Internal Medicine, Ancona University Hospital, Ancona, Italy; 5Department of Car…
Omalizumab outcomes for up to 6 years in pediatric patients with severe persistent allergic asthma
2021
BACKGROUND: Various studies have assessed omalizumab outcomes in the clinical practice setting but follow-up and/or number of patients included were limited. We aim to describe the long-term outcomes of pediatric patients with severe persistent allergic asthma receiving omalizumab in the largest real-life cohort reported to date. METHODS: ANCHORS was a multicenter, observational, retrospective cohort study conducted in 25 Pediatric Allergy and Pulmonology units in Spain. We collected data of patients < 18 years and initiating omalizumab between 2006 and 2018, from the year prior to omalizumab initiation to discontinuation or last available follow-up. The primary outcome was the evolution of…
Sex differences in correlates of intermediate phenotypes and prevalent cardiovascular disease in the general population
2015
Background: There are marked sex differences in cardiovascular disease (CVD) manifestation. It is largely unknown how the distribution of CVD risk factors or intermediate phenotypes explain sex-specific differences. Methods and Results: In 5000 individuals of the population-based Gutenberg Health Study, mean age 55 ± 11 years, 51% males, we examined sex-specific associations of classical CVD risk factors with intima-media thickness, ankle-brachial index, flow-mediated dilation, peripheral arterial tonometry, echocardiographic, and electrocardiographic variables. Intermediate cardiovascular phenotypes were related to prevalent CVD [coronary artery disease, heart failure, stroke, myocardial i…