Search results for " THERAPY"
showing 10 items of 9467 documents
Continuous subcutaneous Insulin infusion leads to immediate, table, and long-term changes in metabolic control
2008
Background: Evaluations of continuous subcutaneous insulin infusion (CSII) usually focus on one pre- and one post-CSII measurement to assess metabolic therapy outcome. Aim: Extending this research, the aim of the present study was to provide a more fine-grained analysis of achieved glycaemic control. Methods: In 52 patients with type 1 diabetes (mean age of 37.85 years at CSII begin; s.d. ± 12.41), haemoglobin A1c (HbA1c) levels were assessed every 3 months over a period of 5 years (1 year before and 4 years after the introduction of CSII). Mixed models were utilized to describe changes in glycaemic control. Results: The pre–post course showed that already in the first quarter, a statis…
Gender differences in usage and user experience of Oiva App
2015
Previous research has indicated that gender is an important demographic to consider when designing effective and tailored technology interventions. Despite this need, gender differences is still an understudied topic in the field of technology interventions. The objective of this study was to study gender differences in usage and user experience of a mental wellness app called Oiva. Gender differences in the app’s effect on the participants’ mental well-being were also investigated. Oiva is a stand-alone mental wellness app that aims to increase its users’ psychological flexibility by teaching Acceptance and Commitment Therapy (ACT) based skills. The study population of the current study wa…
Identity development meets emotional stability : transcending borders through music therapy with an intercultural group of women : a case study
2016
Based on previous investigation, research has revealed the implications of music therapy in women, intercultural groups, and the cultivation of identity and emotional stability. However, the research conducted on the amalgamation of these factors is deficient. The purpose of this case study is to explore the effects of music therapy on the emotional stabilization and development of identity in an intercultural group of women. The umbrella terms of identity development and emotional stability will be dissected based on the sub-themes that have emerged from the therapeutic needs of the intercultural group of individuals involved. Six women from The Netherlands, Iran, China, Russia, Germany, a…
Exploring the practical framework of a multicultural music therapy group for children with emotional and behavioral needs in an after-school setting
2016
Research shows that music therapy is effective in addressing therapeutic goals for groups of children with emotional and behavioral needs. However, most of the current research focuses on behavioral approaches to music therapy with children, and lacks in-depth explanations of practical frameworks surrounding the process (i.e., organizing, planning and implementing a group) for non-directive children’s music therapy groups focused on emotional and behavioral needs in the school setting. The following case study explores the practical framework surrounding a multicultural music therapy group for children with emotional and behavioral needs at an elementary school in Jyväskylä, Finland. The ma…
The relationships among motivational climate, perceived competence, physical performance, and affects during physical education fitness testing lesso…
2021
Despite the prominence of fitness testing in school physical education (PE), there is a sparsity of research examining the antecedents of students’ affective experiences during fitness testing lessons. This study aimed to investigate the associations among task- and ego-involving motivational climates, perceived physical competence, physical performance, enjoyment, and anxiety during two different types of PE fitness testing lessons. Altogether, 645 Finnish students from Grade 5 (50% boys, Mage = 11.2, SD = 0.36) and Grade 8 (47% boys, Mage = 14.2, SD = 0.35) participated in two fitness testing lessons with different content (lesson 1: 20-meter shuttle run test and a test of flexibility; l…
Training practices of Filipino athletes during the early covid-19 lockdown
2022
The imposition of COVID-19 lockdown restricted the daily activities of many people, including athletes. This study investigated the training practices of athletes in the Philippines during the first COVID-19 lockdown. A total of 442 athletes answered an online survey (May-July 2020), with questions pertaining to training practices, such as training frequency and duration. Data were analyzed according to: athlete classification (world-class, international, national, state, or recreational), sport category (individual or team), and sex (male or female). During lockdown, significant reductions in training frequency (except recreational, i.e., lower pre-lockdown training) and duration were obse…
Rational Chemical Multifunctionalization of Graphene Interface Enhances Targeted Cancer Therapy
2020
The synthesis of a drug delivery platform based on graphene was achieved through a step‐by‐step strategy of selective amine deprotection and functionalization. The multifunctional graphene platform, functionalized with indocyanine green, folic acid, and doxorubicin showed an enhanced anticancer activity. The remarkable targeting capacity for cancer cells in combination with the synergistic effect of drug release and photothermal properties prove the great advantage of a combined chemo‐ and phototherapy based on graphene against cancer, opening the doors to future therapeutic applications of this type of material.
Enhancing the Activation and Releasing the Brakes: A Double Hit Strategy to Improve NK Cell Cytotoxicity Against Multiple Myeloma
2018
Natural killer (NK) cells are innate lymphocytes with a strong antitumor ability. In tumor patients, such as multiple myeloma (MM) patients, an elevated number of NK cells after stem cell transplantation (SCT) has been reported to be correlated with a higher overall survival rate. With the aim of improving NK cell use for adoptive cell therapy, we also addressed the cytotoxicity of patient-derived, cytokine-stimulated NK cells against MM cells at specific time points: at diagnosis and before and after autologous stem cell transplantation. Remarkably, after cytokine stimulation, the patients' NK cells did not significantly differ from those of healthy donors. In a small cohort of MM patients…
Role of muscle-targeted nutritional therapy: new data.
2022
Purpose of review To provide an updated overview of recent efficacy data on the use of muscle-targeted nutritional therapy, which should consider the optimization of protein and essential amino acids intakes, possibly in combination with supplementation with vitamin D (correction of deficiency/insufficiency status) and v-3 fatty acids. Recent findings Intervention studies conducted in the last years in different healthcare settings and heterogeneous patient populations support the use of muscle-targeted oral nutritional supplementation to improve muscle mass, function and physical performance in patients with sarcopenia. Higher efficacy is likely to be achieved in combination with individua…
Targeting CD34+ cells of the inflamed synovial endothelium by guided nanoparticles for the treatment of rheumatoid arthritis
2019
Abstract Despite the advances in the treatment of rheumatoid arthritis (RA) achieved in the last few years, several patients are diagnosed late, do not respond to or have to stop therapy because of inefficacy and/or toxicity, leaving still a huge unmet need. Tissue-specific strategies have the potential to address some of these issues. The aim of the study is the development of a safe nanotechnology approach for tissue-specific delivery of drugs and diagnostic probes. CD34 + endothelial precursors were addressed in inflamed synovium using targeted biodegradable nanoparticles (tBNPs). These nanostructures were made of poly-lactic acid, poly-caprolactone, and PEG and then coated with a synovi…